scholarly journals Transdermal Delivery of Naltrexol and Skin Permeability Lifetime after Microneedle Treatment in Hairless Guinea Pigs

2010 ◽  
Vol 99 (7) ◽  
pp. 3072-3080 ◽  
Author(s):  
Stan L. Banks ◽  
Raghotham R. Pinninti ◽  
Harvinder S. Gill ◽  
Kalpana S. Paudel ◽  
Peter A. Crooks ◽  
...  
Keyword(s):  
Transdermal Delivery ◽  
Guinea Pigs ◽  
Skin Permeability ◽  
Hairless Guinea Pigs

Programmable transdermal delivery of nicotine in hairless guinea pigs using carbon nanotube membrane pumps

2012 ◽  
Vol 101 (10) ◽  
pp. 3823-3832 ◽  
Author(s):  
Kalpana S. Paudel ◽  
Ji Wu ◽  
Bruce J. Hinds ◽  
Audra L. Stinchcomb
Keyword(s):  
Carbon Nanotube ◽  
Transdermal Delivery ◽  
Guinea Pigs ◽  
Membrane Pumps ◽  
Hairless Guinea Pigs

Varicella in Hairless Guinea Pigs

1991 ◽  
Vol 163 (4) ◽  
pp. 746-751 ◽  
Author(s):  
M. G. Myers ◽  
B. L. Connelly ◽  
L. R. Stanberry
Keyword(s):  
Guinea Pigs ◽  
Hairless Guinea Pigs

In vivo transdermal iontophoretic delivery of growth hormone releasing factor GRF (1–44) in hairless guinea pigs

1992 ◽  
Vol 18 (3) ◽  
pp. 213-220 ◽  
Author(s):  
Saran Kumar ◽  
Hing Char ◽  
Sunil Patel ◽  
David Piemontese ◽  
A.Waseem Malick ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Guinea Pigs ◽  
Growth Hormone Releasing Factor ◽  
Iontophoretic Delivery ◽  
Hairless Guinea Pigs

Characterization of the Sulfur Mustard Vapor Induced Cutaneous Lesions on Hairless Guinea Pigs

1992 ◽  
Vol 2 (4) ◽  
pp. 242-254 ◽  
Author(s):  
Ernest H. Braue ◽  
Irwin Koplovitz ◽  
Larry W. Mitcheltree ◽  
Edward T. Clayson ◽  
Marty R. Litchfield ◽  
...  
Keyword(s):  
Guinea Pigs ◽  
Sulfur Mustard ◽  
Cutaneous Lesions ◽  
Hairless Guinea Pigs

P09
Comparison between mild irritant response in haired and hairless guinea pigs

2008 ◽  
Vol 50 (3) ◽  
pp. 180-181
Author(s):  
Flemming Andersen ◽  
Kathryn Hedegaard ◽  
Ann Fullerton
Keyword(s):  
Guinea Pigs ◽  
Mild Irritant ◽  
Hairless Guinea Pigs

In vivo evaluation of 3-O-alkyl ester transdermal prodrugs of naltrexone in hairless guinea pigs

2005 ◽  
Vol 102 (2) ◽  
pp. 509-520 ◽  
Author(s):  
Satyanarayana Valiveti ◽  
Dana C. Hammell ◽  
Kalpana S. Paudel ◽  
Mohamed O. Hamad ◽  
Peter A. Crooks ◽  
...  
Keyword(s):  
Guinea Pigs ◽  
Alkyl Ester ◽  
In Vivo Evaluation ◽  
Hairless Guinea Pigs

scholarly journals IONTOPHORETIC TRANSDERMAL DELIVERY OF ANGIOTENSIN II AND ITS ANTAGONISTS

2001 ◽  
Vol 13 (05) ◽  
pp. 242-247
Author(s):  
Yi-You Huang
Keyword(s):  
Angiotensin Ii ◽  
Pulse Duration ◽  
Transdermal Delivery ◽  
Permeation Rate ◽  
Current Intensity ◽  
Delivery Rate ◽  
Skin Permeability ◽  
Pulsed Current ◽  
Key Factors ◽  
Iontophoretic Delivery

Angiotensin II and its antagonists were used as permeant probes to investigate the mechanism of transdermal iontophoretic delivery of peptide/protein drugs and compare the effect of hydrophobic difference between the peptides drugs on the skin permeability. Transport of angiotensin II and its antagonists through excised rabbit pinna skin were enhanced with iontophoresis by monophase periodically pulsed current, amplituide=1mA, frequency=1000Hz and on/off ratio equals 50%. The delivery rate was proportional both to the current intensity and pulse duration of the stimulation. Results showed that the permeation rate of [Sar, Ile] Angiotensin II > [Sar,Ala]Angiotensin II > Angiotensin II. Iontophoretic mobility and hydrophobicity were the key factors dominating the transdermal iontophoretic delivery rate of angiotensin II and its antagonists.

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