Changes in morphology of in situ forming PLGA implant prepared by different polymer molecular weight and its effect on release behavior

2009 ◽  
Vol 98 (1) ◽  
pp. 135-145 ◽  
Author(s):  
Reyhaneh Astaneh ◽  
Mohammad Erfan ◽  
Hamidreza Moghimi ◽  
Hamid Mobedi
2019 ◽  
Vol 55 (5) ◽  
pp. 2090-2100 ◽  
Author(s):  
Hayato Nishikawa ◽  
Eiji Nakata ◽  
Shun Nakano ◽  
Takashi Nakajima ◽  
Takashi Morii

Theranostics ◽  
2012 ◽  
Vol 2 (11) ◽  
pp. 1064-1077 ◽  
Author(s):  
Luis Solorio ◽  
Alexander M. Olear ◽  
Jesse I. Hamilton ◽  
Ravi B. Patel ◽  
Ashlei C. Beiswenger ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Norma A. Cortez-Lemus ◽  
Angel Licea-Claverie ◽  
Francisco Paraguay-Delgado ◽  
Gabriel Alonso-Nuñez

Poly(N,N′-diethylaminoethyl methacrylate) (PDEAEM) with different molecular weights was used to stabilize gold nanoparticles (AuNPs) obtained byin situreduction of tetrachloroauric acid using citrates under acidic conditions and in organic/alcoholic medium. The influence of the pH value on gold nanoparticle size in the presence of PDEAEM was investigated. Results show that the pH of the reacting mixture has a dramatic effect on the size, polydispersity, and morphology of the resulting AuNPs. Moreover, the size of the nanoparticles (NPs) may be modified by changing the solution’s pH or by changing the solvent type. Electron microscope images showed that the sizes of AuNPs coated with PDEAEM were not sensitive to the variation of the polymer molecular weight in the range between 9000 and 29300 g/mol; however their aggregation behavior depended strongly on the polymer molecular weight as revealed by dynamic light scattering studies. AuNPs stabilized with PDEAEM (AuNP@PDEAEM) are stable in water at acidic pH and in organic polar solvents.


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