Investigation of molecular interactions between paclitaxel and DPPC by langmuir film balance and differential scanning calorimetry

2004 ◽  
Vol 93 (1) ◽  
pp. 86-98 ◽  
Author(s):  
Lingyun Zhao ◽  
Si‐Shen Feng ◽  
Mei Lin Go
Keyword(s):  
Differential Scanning Calorimetry ◽  
Molecular Interactions ◽  
Scanning Calorimetry ◽  
Langmuir Film ◽  
Langmuir Film Balance ◽  
Film Balance

Characterization of TwoAcaciaGums and Their Fractions Using a Langmuir Film Balance

2000 ◽  
Vol 48 (7) ◽  
pp. 2709-2712 ◽  
Author(s):  
Marie-Laure Fauconnier ◽  
Christophe Blecker ◽  
Joëlle Groyne ◽  
Hary Razafindralambo ◽  
Emmanuel Vanzeveren ◽  
...  
Keyword(s):  
Langmuir Film ◽  
Langmuir Film Balance ◽  
Film Balance

Phospholipid – protein molecular interactions. 2. Raman spectroscopic and calorimetric studies of phospholipids – polylysine and phospholipid – histones interactions in model membranes

1985 ◽  
Vol 63 (7) ◽  
pp. 1390-1393 ◽  
Author(s):  
A. Bertoluzza ◽  
S. Bonora ◽  
G. Fini ◽  
M. A. Morelli
Keyword(s):  
Differential Scanning Calorimetry ◽  
Raman Spectroscopy ◽  
Molecular Interactions ◽  
Protein Fraction ◽  
Model Membranes ◽  
Polar Component ◽  
Water Interface ◽  
Scanning Calorimetry ◽  
Raman Spectroscopic ◽  
Calorimetric Studies

Dimyristoylphosphatidylcholine (DMPC) – polylysine and DMPC–histones systems have been studied by Raman spectroscopy and differential scanning calorimetry. The results of both techniques indicate that the interactions are mainly confined to the lipid–water interface. The protein fraction of histones giving rise to a partial penetration into the bilayer is not the lysine-rich fraction but rather the non-polar component of the proteins. On the basis of the results obtained, the formation of lipoprotein complexes between histones and DMPC appears to be ruled out.

Langmuir film balance study of the interactions between carbohydrates and phospholipid monolayers

Biochemistry ◽  
1984 ◽  
Vol 23 (26) ◽  
pp. 6912-6919 ◽  
Author(s):  
David Samuel Johnston ◽  
Elizabeth Coppard ◽  
Gregorio Valencia Parera ◽  
Dennis Chapman
Keyword(s):  
Langmuir Film ◽  
Balance Study ◽  
Langmuir Film Balance ◽  
Phospholipid Monolayers ◽  
Film Balance

HCl causes less intracellular acidification inNecturus gastric mucosa surface epithelial cells than other acids

2001 ◽  
Vol 281 (3) ◽  
pp. G675-G680 ◽  
Author(s):  
O. Nylander-Koski ◽  
H. Mustonen ◽  
I. Vikholm ◽  
T. Kiviluoto ◽  
E. Kivilaakso
Keyword(s):  
Hydrogen Bonding ◽  
Intracellular Ph ◽  
Gastric Epithelium ◽  
Lower Amount ◽  
Physicochemical Interaction ◽  
Intracellular Acidification ◽  
Langmuir Film ◽  
Langmuir Film Balance ◽  
Head Groups ◽  
Film Balance

Luminal acid causes intracellular acidification in the gastric epithelium, but the mechanism by which H+ enters surface cells remains obscure. This study addressed the problem by assessing how different acids affect intracellular pH in gastric surface cells. Isolated Necturus maculosus antral mucosa was exposed to HCl, HNO3, H2SO4, and H3PO4 at pH 2.30. Intracellular pH was measured with microelectrodes. The physicochemical interaction of a synthetic model of gastric phospholipids with the different acids was studied using Langmuir film balance. Exposure to luminal HNO3, H2SO4, or H3PO4 caused significantly larger intracellular acidification than exposure to HCl. The degree of acidification was not dependent on the valence or nature of the anionic counterion of the acid but significantly correlated with the amount of molecular acid. By Langmuir film balance, subphases acidified with HNO3, H2SO4, or H3PO4 caused more close packing of phospholipid molecules than those acidified with HCl, possibly allowing hydrogen bonding between head groups to facilitate H+ movement across the phospholipid membrane. HCl causes significantly less intracellular acidification in gastric epithelium than HNO3, H2SO4, or H3PO4. This may be caused by the lower amount of molecular HCl in solution and possible hydrogen bonding between the head groups of phospholipid molecules and the other acids.

A contribution to the theory of the Langmuir film balance

1953 ◽  
Vol 30 (9) ◽  
pp. 342-342
Author(s):  
H Zierfuss ◽  
E Eisma ◽  
P C Blokker
Keyword(s):  
Langmuir Film ◽  
Langmuir Film Balance ◽  
Film Balance
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