Dose-Independent Pharmacokinetics of a New Reversible Proton Pump Inhibitor, KR-60436, after Intravenous and Oral Administration to Rats: Gastrointestinal First-Pass Effect

2003 ◽  
Vol 92 (8) ◽  
pp. 1592-1603 ◽  
Author(s):  
Su Yeon Yu ◽  
Soo Kyung Bae ◽  
Eun Jung Kim ◽  
Yoon Gyoon Kim ◽  
Sun-Ok Kim ◽  
...  
Keyword(s):  
Proton Pump Inhibitor ◽  
Oral Administration ◽  
Proton Pump ◽  
First Pass Effect ◽  
First Pass ◽  
Intravenous And Oral Administration

Gastrointestinal First-pass Effect of YJA-20379-8, a New Reversible Proton Pump Inhibitor, in Rats

1999 ◽  
Vol 51 (9) ◽  
pp. 1031-1036 ◽  
Author(s):  
JONGHAN KIM ◽  
EUN J. KIM ◽  
KYE S. HAN ◽  
MAN S. CHANG ◽  
MYUNG G. LEE
Keyword(s):  
Proton Pump Inhibitor ◽  
Proton Pump ◽  
First Pass Effect ◽  
First Pass

Influence of First-Pass Effect on Availability of Drugs on Oral Administration

1971 ◽  
Vol 60 (9) ◽  
pp. 1338-1340 ◽  
Author(s):  
M. Gibaldi ◽  
R.N. Boyes ◽  
S. Feldman
Keyword(s):  
Oral Administration ◽  
First Pass Effect ◽  
First Pass

Effect of food and a proton pump inhibitor on the pharmacokinetics of S-1 following oral administration of S-1 in patients with advanced solid tumors

2011 ◽  
Vol 69 (3) ◽  
pp. 753-761 ◽  
Author(s):  
Max E. Scheulen ◽  
Kaku Saito ◽  
Ralf A. Hilger ◽  
Bastian Mende ◽  
Christopher Zergebel ◽  
...  
Keyword(s):  
Proton Pump Inhibitor ◽  
Oral Administration ◽  
Solid Tumors ◽  
Proton Pump ◽  
Advanced Solid Tumors ◽  
Effect Of Food
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