Comparison of effects of different ointment bases on the penetration of ketoprofen through heat-separated human epidermis and artificial lipid barriers

2003 ◽  
Vol 92 (7) ◽  
pp. 1396-1406 ◽  
Author(s):  
Elke Jaeckle ◽  
Ulrich F. Schaefer ◽  
Helmut Loth
Author(s):  
A. P. Lupulescu ◽  
H. Pinkus ◽  
D. J. Birmingham

Our laboratory is engaged in the study of the effect of different chemical agents on human skin, using electron microscopy. Previous investigations revealed that topical use of a strong alkali (NaOH 1N) or acid (HCl 1N), induces ultrastructural changes in the upper layers of human epidermis. In the current experiments, acetone and kerosene, which are primarily lipid solvents, were topically used on the volar surface of the forearm of Caucasian and Negro volunteers. Skin specimens were bioptically removed after 90 min. exposure and 72. hours later, fixed in 3% buffered glutaraldehyde, postfixed in 1% phosphate osmium tetroxide, then flat embedded in Epon.


1965 ◽  
Vol 92 (4) ◽  
pp. 462-468 ◽  
Author(s):  
W. L. Epstein
Keyword(s):  

2018 ◽  
Vol 6 (1) ◽  
pp. 64 ◽  
Author(s):  
Rodrigo De Vecchi ◽  
Vanja Dakic ◽  
Guilherme Mattos ◽  
Anne-Sophie Rigaudeau ◽  
Veronica Oliveira ◽  
...  

2020 ◽  
Vol 29 (7) ◽  
pp. 616-622 ◽  
Author(s):  
Attila Oláh ◽  
Majid Alam ◽  
Jérémy Chéret ◽  
Nikolett Gréta Kis ◽  
Zoltán Hegyi ◽  
...  

Mycoses ◽  
2019 ◽  
Vol 62 (12) ◽  
pp. 1194-1201 ◽  
Author(s):  
Ana Filipa Pedrosa ◽  
Carmen Lisboa ◽  
Joana Branco ◽  
Ana C. Almeida ◽  
Claudia Mendes ◽  
...  

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