Improvement of solubility and oral bioavailability of a poorly water‐soluble drug, TAS‐301, by its melt‐adsorption on a porous calcium silicate

2002 ◽  
Vol 91 (2) ◽  
pp. 362-370 ◽  
Author(s):  
Masahiro Kinoshita ◽  
Kazuhiko Baba ◽  
Atushi Nagayasu ◽  
Kanoo Yamabe ◽  
Takashi Shimooka ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
Calcium Silicate ◽  
Water Soluble ◽  
Water Soluble Drug ◽  
Poorly Water Soluble ◽  
Poorly Water Soluble Drug

scholarly journals In vivo evaluation of modified gum karaya as a carrier for improving the oral bioavailability of a poorly water-soluble drug, nimodipine

2002 ◽  
Vol 3 (2) ◽  
pp. 55-63 ◽  
Author(s):  
Gedela V. Murali Mohan Babu ◽  
Namballa R. Kumar ◽  
Kasina H. Sankar ◽  
Battu J. Ram ◽  
Namburu K. Kumar ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
Water Soluble ◽  
In Vivo Evaluation ◽  
Gum Karaya ◽  
Water Soluble Drug ◽  
Poorly Water Soluble ◽  
Poorly Water Soluble Drug

Enhanced Oral Bioavailability of a Poorly Water Soluble Drug PNU‐91325 by Supersaturatable Formulations

2004 ◽  
Vol 30 (2) ◽  
pp. 221-229 ◽  
Author(s):  
Ping Gao ◽  
Michael E. Guyton ◽  
Tiehua Huang ◽  
Juliane M. Bauer ◽  
Kevin J. Stefanski ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
Water Soluble ◽  
Water Soluble Drug ◽  
Poorly Water Soluble ◽  
Poorly Water Soluble Drug

Optimization and bioavailability evaluation of self-microemulsifying drug delivery system of the daidzein–nicotinamide complex

RSC Advances ◽  
2016 ◽  
Vol 6 (113) ◽  
pp. 112686-112694 ◽  
Author(s):  
Zun Huang ◽  
Jing Xia ◽  
Jing Li ◽  
Xuan Gao ◽  
Yiyue Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Bioavailability ◽  
Water Soluble ◽  
Water Soluble Drug ◽  
Poorly Water Soluble ◽  
Poorly Water Soluble Drug

In this study, a DDZ–NCT complex SMEDDS was prepared and optimized to improve the oral bioavailability of the poorly water-soluble drug.

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