Polyhedral boron derivatives of porphyrins and phthalocyanines

2001 ◽  
Vol 05 (11) ◽  
pp. 767-781 ◽  
Author(s):  
VLADIMIR I. BREGADZE ◽  
IGOR B. SIVAEV ◽  
DETLEF GABEL ◽  
DIETER WÖHRLE

The synthesis of compounds containing polyhedral boron cages and porphyrin or phthalocyanine units connected covalently in one molecule is reviewed. The importance of these compounds arises, on the one hand, from the use of polyhedral boron derivatives in neutron capture therapy for cancer; on the other hand, porphyrins and phthalocyanines are known as photosensitizers in photodynamic tumor therapy. Current interest in the binding of polyhedral boron compounds to porphyrins and phthalocyanines is due to the observation that porphyrins and phthalocyanines show improved uptake and good persistence in tissues. Medical applications of compounds containing polyhedral boron cages and porphyrin or phthalocyanine units in one molecule are briefly discussed.

2001 ◽  
Vol 71 (1) ◽  
pp. 21-35 ◽  
Author(s):  
J. A. Hernández ◽  
J. Sanz

AbstractWe give an example of a holomorphic function, admitting Gérard-Sibuya asymptotic expansion on a polysector of Cn, and such that none of its derivatives admits such an expansion. This motivates the study of the relationship between the concepts of asymptotic expansion in several variables respectively given by Gérard-Sibuya and Majima. For a function f, Majima's notion is proved to be equivalent, on the one hand, to the existence of Gérard-Sibuya asymptotic expansion for f and its derivatives, and on the other hand, to the boundedness of the derivatives of f on bounded proper subpolysectors of S.


2019 ◽  
Vol 4 (2) ◽  
pp. 452-475 ◽  
Author(s):  
Annette Arlander

Is it possible to respond to the challenge of a philosopher with artistic means, rather than on the one hand by attempting to philosophize, or on the other hand by resorting to illustration or application? Perhaps it is not. This text is nevertheless an attempt at responding to the challenge posed to artists by Michael Marder who, in volume 1 of this journal, challenged philosophers and artists ‘to include the spatiality, movement, and perspective of the vegetal in their work’ (Marder 2015, 192). The artistic research project ‘Performing with plants’ could be understood as a response to this challenge. In this text I will briefly outline the plan for the project, relate it to the current interest in plant thinking, plant theory and new materialist feminist theory and then focus on some works loosely related to the project, which seem to resonate with Marder’s challenge in some sense. The variations of Resting with Pines performed in September 2017 in Nida Art Colony on the Curonian spit in Lithuania will serve as attempts to include and even emulate the vegetal, and as an example of a characteristic common to many performance practices, namely the tendency to go on, to ‘keep growing’.


2006 ◽  
Vol 10 (11) ◽  
pp. 1293-1300 ◽  
Author(s):  
Andrej Semioshkin ◽  
Olga Tsaryova ◽  
Olga Zhidkova ◽  
Vladimir Bregadze ◽  
Dieter Wöhrle

The reactions of dodecahydro-closo-dodecaborate oxonium derivatives with various phenols resulted in phenoxy-undecahydro-closo-dodecaborates in high yields. Using this method, a phthalocyanine zinc(II) complex containing four ( B 12 H 12)2- species was prepared in high yield. The compound shows good photocatalytic activity. The combination of boron cages and phthalocyanines makes this compound useful for boron neutron capture therapy for cancer and photodynamic tumor therapy.


Author(s):  
T.A. Korneyeva ◽  

Zero suffixation in Anna Akhmatova’s poetic texts was studied. The textual analysis of A. Akhmatova’s early poems rich in nominals with various types of zero suffixation was performed. Comparison with her later poems was carried out. On the one hand, this approach shows A. Akhmatova’s desire to overcome the traditions of symbolism and her attempts to develop an original style. On the other hand, nominals with zero suffixation clearly prevailed in A. Akhmatova’s early poems as compared with the later works. Particular attention was paid to the role of nominals with zero suffixation in the poetic space organization of two poetry collections: “Evening” (‘Vecher’) and “Beads” (‘Chetki’). We considered lexical, word-building, syntagmatic, grammatical, stylistic, tropeic, and other features of derivatives of zero suffixes in these poetry collections. It was revealed that nominals with zero suffixation were mainly used as a means of concentration of meanings and embodiment of the special drama of the poet’s lyrical monologue. The results of the research are important for expanding the knowledge on the text-forming function of word formation and, in particular, nominals with zero suffixation.


Author(s):  
Karl-Werner Schweppe

AbstractOral progestins without an estrogen component have been described to be effective in the treatment of endometriosis. Several different substances have been tested, which are on the one hand derivatives of the natural progesterone or of the C-17-OH-progesteron, or on the other hand derivatives of C-19-nortestosteron. Their common characteristic is the secretory transformation of estrogen primed uterine endometrium for which different dosages are necessary because of their different biological activities. They are different with regard to their profile and potency of action on hypothalamicpituitary axis, metabolic processes, breast tissue and genital organs. They are effectively similar with regard to endometriosis related complaints if sufficient doses are administered. No effects are noted on reduced fertility in endometriotic patients and the data are inconsistent concerning direct effects on the endometriotic cells.


Author(s):  
Stefan Krause ◽  
Markus Appel

Abstract. Two experiments examined the influence of stories on recipients’ self-perceptions. Extending prior theory and research, our focus was on assimilation effects (i.e., changes in self-perception in line with a protagonist’s traits) as well as on contrast effects (i.e., changes in self-perception in contrast to a protagonist’s traits). In Experiment 1 ( N = 113), implicit and explicit conscientiousness were assessed after participants read a story about either a diligent or a negligent student. Moderation analyses showed that highly transported participants and participants with lower counterarguing scores assimilate the depicted traits of a story protagonist, as indicated by explicit, self-reported conscientiousness ratings. Participants, who were more critical toward a story (i.e., higher counterarguing) and with a lower degree of transportation, showed contrast effects. In Experiment 2 ( N = 103), we manipulated transportation and counterarguing, but we could not identify an effect on participants’ self-ascribed level of conscientiousness. A mini meta-analysis across both experiments revealed significant positive overall associations between transportation and counterarguing on the one hand and story-consistent self-reported conscientiousness on the other hand.


2005 ◽  
Vol 44 (03) ◽  
pp. 107-117
Author(s):  
R. G. Meyer ◽  
W. Herr ◽  
A. Helisch ◽  
P. Bartenstein ◽  
I. Buchmann

SummaryThe prognosis of patients with acute myeloid leukaemia (AML) has improved considerably by introduction of aggressive consolidation chemotherapy and haematopoietic stem cell transplantation (SCT). Nevertheless, only 20-30% of patients with AML achieve long-term diseasefree survival after SCT. The most common cause of treatment failure is relapse. Additionally, mortality rates are significantly increased by therapy-related causes such as toxicity of chemotherapy and complications of SCT. Including radioimmunotherapies in the treatment of AML and myelodyplastic syndrome (MDS) allows for the achievement of a pronounced antileukaemic effect for the reduction of relapse rates on the one hand. On the other hand, no increase of acute toxicity and later complications should be induced. These effects are important for the primary reduction of tumour cells as well as for the myeloablative conditioning before SCT.This paper provides a systematic and critical review of the currently used radionuclides and immunoconjugates for the treatment of AML and MDS and summarizes the literature on primary tumour cell reductive radioimmunotherapies on the one hand and conditioning radioimmunotherapies before SCT on the other hand.


2003 ◽  
pp. 15-26
Author(s):  
P. Wynarczyk
Keyword(s):  
The Core ◽  

Two aspects of Schumpeter' legacy are analyzed in the article. On the one hand, he can be viewed as the custodian of the neoclassical harvest supplementing to its stock of inherited knowledge. On the other hand, the innovative character of his works is emphasized that allows to consider him a proponent of hetherodoxy. It is stressed that Schumpeter's revolutionary challenge can lead to radical changes in modern economics.


2018 ◽  
Vol 4 (1) ◽  
pp. 67-84
Author(s):  
Wahyudin Noor

Abstract Pesantren are often associated with backwardness and traditionalism in everything: facilities, technology, learning methods, and even the curriculum. For now, it seems like the traditional term for pesantren is no longer relevant enough. The pace of movement in the era of renewal marked by the rapid development of technology has demanded pesantren to make adjustments. However, on the one hand, when viewed from the direction of change, the reform efforts pursued by pesantren are not to erase the old tradition, but merely to add something new so that the old tradition and conditions can be maintained while accepting the presence of a new one. On the other hand, the reform efforts undertaken by pesantren have implications for the fact that the typical values of the pesantren are fading away. Abstrak  Pesantren seringkali diasosiasikan dengan keterbelakangan dan tradisional dalam segala hal: fasilitas, teknologi, metode pembelajaran, dan bahkan kurikulumnya. Untuk saat ini, sepertinya istilah tradisional untuk pesantren, sudah tidak lagi cukup relevan. Laju gerak pembaharuan zaman yang ditandai dengan pesatnya perkembangan teknologi telah menuntut pesantren untuk melakukan penyesuaian diri. Kendatipun demikian, di satu sisi, jika dilihat dari arah perubahan, upaya pembaharuan yang ditempuh pesantren tidaklah untuk menghapus tradisi yang lama, tetapi sekadar menambah dengan sesuatu yang baru sehingga tradisi maupun kondisi yang lama bisa dipertahankan sambil menerima kehadiran yang baru. Di sisi yang lain, upaya pembaharuan yang dilakukan pesantren ternyata berimplikasi pada kenyataan akan semakin pudarnya nilai-nilai khas yang dimiliki oleh pesantren.


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