Bolus Gastric Feeds Improve Nutritional Delivery to Mechanically Ventilated Pediatric Medical Patients: Results of the COntinuous vs BOlus (COBO2) Multi‐Center Trial

2021 ◽  
Author(s):  
Ann‐Marie Brown ◽  
Sharon Y. Irving ◽  
Charlene Pringle ◽  
Christine Allen ◽  
Miraides F. Brown ◽  
...  
Keyword(s):  
Medical Patients ◽  
Mechanically Ventilated

scholarly journals Potential Value of Regionalized Intensive Care for Mechanically Ventilated Medical Patients

2008 ◽  
Vol 177 (3) ◽  
pp. 285-291 ◽  
Author(s):  
Jeremy M. Kahn ◽  
Walter T. Linde-Zwirble ◽  
Hannah Wunsch ◽  
Amber E. Barnato ◽  
Theodore J. Iwashyna ◽  
...  
Keyword(s):  
Intensive Care ◽  
Medical Patients ◽  
Mechanically Ventilated ◽  
Potential Value

scholarly journals Study of the Effect of Early Versus Delayed Enteral Nutrition inCritically Ill Mechanically Ventilated Medical Patients

2021 ◽  
Vol 89 (3) ◽  
pp. 53-62
Author(s):  
MERVAT M. MARZOUK, M.D.; MANAL K. SHAMS, M.D. ◽  
DIAA ELDIN Sh. ELAWADY, M.D.; andAHMED A.H. ELSEDEK, M.Sc.
Keyword(s):  
Enteral Nutrition ◽  
Medical Patients ◽  
Mechanically Ventilated

Delirium as detected by the CAM-ICU predicts restraint use among mechanically ventilated medical patients*

2005 ◽  
Vol 33 (6) ◽  
pp. 1260-1265 ◽  
Author(s):  
Scott T. Micek ◽  
Nitin J. Anand ◽  
Brad R. Laible ◽  
William D. Shannon ◽  
Marin H. Kollef
Keyword(s):  
Medical Patients ◽  
Mechanically Ventilated ◽  
Restraint Use

Prediction of Glomerular Filtration Rate Using Aminoglycoside Clearance in Critically Ill Medical Patients

1992 ◽  
Vol 26 (10) ◽  
pp. 1205-1210 ◽  
Author(s):  
Barbara J. Zarowitz ◽  
Sylvie Robert ◽  
Edward L. Peterson
Keyword(s):  
Glomerular Filtration Rate ◽  
Creatinine Clearance ◽  
Glomerular Filtration ◽  
Critically Ill ◽  
Filtration Rate ◽  
Preliminary Investigation ◽  
Tertiary Care ◽  
Serum Concentrations ◽  
Medical Patients ◽  
Mechanically Ventilated

OBJECTIVE: The aim of this preliminary investigation was to evaluate the use of aminoglycoside serum concentrations as a surrogate measure of the glomerular filtration rate (GFR) in comparison with other measured and empiric methods against inulin, the criterion standard measure of GFR. DESIGN: A consecutive sample of all eligible patients. SETTING: An eight-bed medical intensive care unit in a university-affiliated tertiary-care teaching hospital. PATIENTS: Ten critically ill medical patients receiving gentamicin or tobramycin for presumed or documented gram-negative bacillary infection were enrolled in the study. The patients were mechanically ventilated and had underlying organ system dysfunction. All ten patients completed the study. INTERVENTION: Patients underwent renal functional assessment by measured inulin (Clin) and 24-hour urinary creatinine clearance (Clcr). Aminoglycoside serum concentrations were used to estimate GFR and were compared with the two measured methods and a creatinine clearance calculated with the Cockcroft-Gault method (ClCG). All evaluations were performed the same day. RESULTS: Clin averaged 51.6 ± 35.0 mL/min and serum creatinine ranged from 0.3 to 5.4 mg/dL (26.5 to 477.3 μmol/L). Steady-state peak and trough aminoglycoside concentrations were 6.1 ± 1.4 and 1.3 ± 0.9 μg/mL, respectively. There were no statistically significant differences between the various methods, although the aminoglycoside-calculated GFR (Clamg) 95 percent confidence intervals were smaller man Clcr and ClCG compared with Clin. Mean absolute errors were smaller with Clamg than with Clcr and ClCG. Regression results indicated that only Clang and ClCG demonstrated agreement with Clin (lines not different from y=x). However, the Clamg showed closer agreement, with a mean square error almost half that of ClCG (9.6 vs. 18.1). CONCLUSIONS: Clamg can be used routinely as an estimate of GFR in critically ill patients, with less error man empiric methods.

scholarly journals Comparison between Dexmedetomidine and Propofol for Sedation in Mechanically Ventilated Intensive Care Patients

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
F S Latif ◽  
W R H Thabet ◽  
D M Haiba ◽  
M A A Ebrahim
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Study Groups ◽  
Apache Ii Score ◽  
Medical Patients ◽  
Laboratory Findings ◽  
Mechanically Ventilated ◽  
Intensive Care Patients ◽  
Intravascular Devices

Abstract Background Critically ill patients are submitted to several interventions that can lead to distress and pain, like endotracheal intubation, mechanical ventilation, and central venous and arterial catheterization. Indeed, pain is one of the most common memories from patients admitted to intensive care unit (ICU) and can lead to agitation and its consequences, as accidental extubation, and removal of intravascular devices. Accordingly, one of the most used drugs for patients in the ICU are sedatives and analgesics Objectives The aim of the study is to compare dexmedetomidine and propofol for sedation in mechanically ventilated intensive care patients according to vital data and laboratory findings during sedation to figure out efficacy and safety profiles between both drugs in sedation, weaning and facilitating extubation in intensive care unit Patients and Methods This study was performed on 40 patients divided into 2 groups equally one group received propofol and the other group received dexmedetomidine as a sedative during mechanical ventilation. We collected vital and heamodynamics data and laboratory findings during the time of sedation in ICU. Results All the 40 patients completed the study. The demographic profiles of both the groups were comparable. These groups were also comparable with respect to baseline vital parameters and baseline investigations. The study groups included both surgical and medical patients. There were no statistically significant differences between the two patient groups with respect to age, weight, gender and APACHE II score. Conclusion This study evaluated dexmedetomidine versus propofol for sedation in mechanicaly ventilated patients in ICU. We conclude that adequate level of sedation can be achieved by both dexmedetomidine and propofol

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