Renal function in patients with intestinal failure receiving home parenteral support

2021 ◽  
Author(s):  
SophieMaria Mathiesen ◽  
KristianAsp Fuglsang ◽  
Giovanna Ranzato ◽  
Thomas Scheike ◽  
PalleBekker Jeppesen
Keyword(s):  
Renal Function ◽  
Intestinal Failure ◽  
Parenteral Support

scholarly journals Measurement of Utilities Associated with Parenteral Support Requirement in Patients with Short Bowel Syndrome and Intestinal Failure

2018 ◽  
Vol 40 (11) ◽  
pp. 1878-1893.e1 ◽  
Author(s):  
Rachel Ballinger ◽  
Jake Macey ◽  
Andrew Lloyd ◽  
John Brazier ◽  
Joanne Ablett ◽  
...  
Keyword(s):  
Short Bowel Syndrome ◽  
Intestinal Failure ◽  
Short Bowel ◽  
Parenteral Support

SUN-PO133: Assessment of Renal Function in Home Parenteral Nutrition Patients for Intestinal Failure

2019 ◽  
Vol 38 ◽  
pp. S109
Author(s):  
M. Lauverjat ◽  
S. Ait ◽  
C. Bergoin ◽  
L. Koppe ◽  
D. Barnoud ◽  
...  
Keyword(s):  
Renal Function ◽  
Parenteral Nutrition ◽  
Intestinal Failure ◽  
Home Parenteral Nutrition

Teduglutide reduced parenteral support in children with short bowel syndrome associated-intestinal failure: a phase 3 study

2019 ◽  
Vol 29 ◽  
pp. 251-252
Author(s):  
S. Hill ◽  
S.A. Kocoshis ◽  
B.A. Carter ◽  
R.S. Venick ◽  
P.W. Wales ◽  
...  
Keyword(s):  
Short Bowel Syndrome ◽  
Intestinal Failure ◽  
Phase 3 ◽  
Short Bowel ◽  
Parenteral Support

753 - Catheter-Related Bloodstream Infections in Patients with Intestinal Failure Dependent on Home Parenteral Support: Evaluation of a Catheter-Salvage-Strategy

2018 ◽  
Vol 154 (6) ◽  
pp. S-159
Author(s):  
Siri Tribler ◽  
Christopher F. Brandt ◽  
Kristian A. Fuglsang ◽  
Michael Staun ◽  
Per Broebech ◽  
...  
Keyword(s):  
Intestinal Failure ◽  
Bloodstream Infections ◽  
Parenteral Support ◽  
Support Evaluation

scholarly journals PE-8: Relation Between Surgical Procedures, Chronic Intestinal Failure and Dependency on Parenteral Support

2021 ◽  
Vol 105 (7S) ◽  
pp. S33-S33
Author(s):  
Iyer K ◽  
Mercer D ◽  
Pfeffer D ◽  
Brøsted Zimmermann L ◽  
Berner-Hansen M ◽  
...  
Keyword(s):  
Surgical Procedures ◽  
Intestinal Failure ◽  
Parenteral Support

scholarly journals Evolution of renal function in patients with severe intestinal failure on home parenteral nutrition

2020 ◽  
Author(s):  
Elodie Chalencon ◽  
Laetitia Koppe ◽  
Madeleine Lauverjat ◽  
Didier Barnoud ◽  
Denis Fouque ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Disease ◽  
Parenteral Nutrition ◽  
Intestinal Failure ◽  
Significant Risk ◽  
Home Parenteral Nutrition ◽  
Predisposing Factor ◽  
Gold Standard Method ◽  
Renal Function Decline ◽  
Disease Epidemiology

Abstract Background Kidney disease is a frequent but underestimated complication in patients suffering from intestinal failure (IF) treated by long-term home parenteral nutrition (HPN). The evolution in glomerular filtration rate (GFR) over time is poorly characterized. The current equations for estimating GFR have limited precision. No study has specifically investigated the reliability of recent creatinine-based estimated GFR (eGFR) equations in this population. The aim of this study was to evaluate the renal function decline under home parenteral nutrition (HPN) with a gold standard method and compare the performances of routinely used eGFR equations. Methods Forty patients with HPN and two or more GFR measurements were retrospectively studied. The renal function decline was calculated by the slope drawn between the successive measured GFRs (mGFRs). The performances of the Modification of Diet in Renal Disease, Chronic Kidney Disease Epidemiology Collaboration, full age spectrum and revised Lund–Malmö equations were compared with reference methods (inulin or iohexol clearance). Results The mean mGFR was 78 ± 28 mL/min/1.73 m2. The annual decline of mGFR was −1.9 mL/min/1.73 m2/year. No predisposing factor was identified to predict impairment in renal function. eGFR formulas grossly overestimated mGFR and had a low level of accuracy. Conclusions Patients with IF are at significant risk for impaired renal function. In this population, the tested eGFR equations were inaccurate. However, monitoring kidney function with mGFR remains important in these patients, as their GFR regularly declines and no specific risk factor has yet been identified.

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