Bone Mineral Composition Among Long‐Term Parenteral Nutrition Patients: Postmortem Assessment of Calcium, Phosphorus, Magnesium, and Select Trace Elements

2020 ◽  
Author(s):  
Aubrey L. Galusha ◽  
Lyn J. Howard ◽  
Pamela C. Kruger ◽  
Tia Marks ◽  
Patrick J. Parsons
Keyword(s):  
Trace Elements ◽  
Parenteral Nutrition ◽  
Mineral Composition ◽  
Bone Mineral ◽  
Calcium Phosphorus

Trace Element Status (Zinc, Copper, Selenium, Iron, Manganese) in Patients with Long-Term Home Parenteral Nutrition

2016 ◽  
Vol 69 (2) ◽  
pp. 120-124 ◽  
Author(s):  
Milan Dastych Jr. ◽  
Michal Šenkyřík ◽  
Milan Dastych ◽  
František Novák ◽  
Petr Wohl ◽  
...  
Keyword(s):  
Trace Elements ◽  
Parenteral Nutrition ◽  
Blood Plasma ◽  
Whole Blood ◽  
Statistical Significance ◽  
Home Parenteral Nutrition ◽  
Control Group ◽  
The Status ◽  
In Blood Plasma

Background: The objective of the present study was to determine concentrations of zinc (Zn), copper (Cu), iron (Fe), selenium (Se) in blood plasma and manganese (Mn) in the whole blood in patients with long-term home parenteral nutrition (HPN) in comparison to the control group. Patients and Methods: We examined 68 patients (16 men and 52 women) aged from 28 to 68 years on a long-term HPN lasting from 4 to 96 months. The short bowel syndrome was an indication for HPN. The daily doses of Zn, Cu, Fe, Se and Mn in the last 3 months were determined. Results: No significant differences in blood plasma were found for Zn, Cu and Fe in patients with HPN and in the control group (p > 0.05). The concentration of Mn in whole blood was significantly increased in HPN patients (p < 0.0001), while Se concentration in these patients was significantly decreased (p < 0.005). The concentration of Mn in the whole blood of 16 patients with cholestasis was significantly increased compared to the patients without cholestasis (p < 0.001). The Cu concentration was increased with no statistical significance. Conclusion: In long-term HPN, the status of trace elements in the patients has to be continually monitored and the daily substitution doses of these elements have to be flexibly adjusted. Dosing schedule needs to be adjusted especially in cases of cholestatic hepatopathy. A discussion about the optimal daily dose of Mn in patients on HPN is appropriate. For clinical practice, the availability of a substitution mixture of trace elements lacking Mn would be advantageous.

scholarly journals Erratum to: How does long-term parenteral nutrition impact the bone mineral status of children with intestinal failure?

2010 ◽  
Vol 28 (3) ◽  
pp. 359-359
Author(s):  
Antonella Diamanti ◽  
Carla Bizzarri ◽  
Maria Sole Basso ◽  
Manuela Gambarara ◽  
Marco Cappa ◽  
...  
Keyword(s):  
Parenteral Nutrition ◽  
Bone Mineral ◽  
Intestinal Failure ◽  
Mineral Status ◽  
Bone Mineral Status

scholarly journals Balance study of twenty trace elements during total parenteral nutrition in man

1977 ◽  
Vol 37 (1) ◽  
pp. 107-126 ◽  
Author(s):  
S. Jacobson ◽  
P.-O. Wester
Keyword(s):  
Trace Elements ◽  
Parenteral Nutrition ◽  
Total Parenteral Nutrition ◽  
Cobalt Chromium ◽  
Fat Emulsion ◽  
Balance Study ◽  
Directional Change ◽  
Male Patients ◽  
Exchange Technique

1. Balances of twenty trace elements (silver, arsenic, gold, bromine, cadmium, cobalt, chromium, caesium, copper, iron, mercury, lanthanum, molybdenum, rubidium, antimony, scandium, selenium, samarium, tungsten and zinc) have been determined in four male patients during total parenteral nutrition including fat emulsion and a special solution for addition of Fe, Zn, manganese, Cu, fluorine and iodine, besides calcium and magnesium, to the infusion solutions.2. The analyses for trace elements were made with the aid of an ion-exchange technique based on neutron activation, and combined with subsequent gamma spectrometry.3. The intended intravenous supply of trace elements corresponded approximately to the analysed supply. However, all the other trace elements determined were found to be unintentionally administered in small amounts.4. There was a substantial retention of Fe. Other elements retained were Ag, Co, Cr, Cu, Sb, Sc and W.5. Particularly Br and Rb were lost by the patients, but negative balances were also found for As, Au, Cd, Cs, Mo, Se and Zn. However, Zn was retained by one patient with short bowel syndrome.6. The serum concentrations of thirteen (Ag, Br, Co, Cs, Cu, Fe, Hg, Mo, Rb, Sc, Se, W and Zn) of the trace elements were found to have some decrease during the period of total parenteral nutrition, mostly in accordance with the corresponding balance values. Fe, in particular, was found to have the directional change in concentration.7. The administration of trace elements is recommended in long-term total parenteral nutrition.

PP129-MON BONE MINERAL DENSITY IN CHILDREN RECEIVING LONG-TERM PARENTERAL NUTRITION

2012 ◽  
Vol 7 (1) ◽  
pp. 189
Author(s):  
K. Olszewska ◽  
E. Banaś ◽  
M. Kaleta ◽  
M. Jaworski ◽  
K. Popińska ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Parenteral Nutrition ◽  
Bone Mineral ◽  
Mineral Density

PTH-215 Trace elements and vitamin levels in long-term home parenteral nutrition paediatric patients

Gut ◽  
2015 ◽  
Vol 64 (Suppl 1) ◽  
pp. A504.2-A504
Author(s):  
R Núñez-Ramos ◽  
S Gallego ◽  
D Gayda-Pimlott ◽  
S Macdonald ◽  
J Koeglmeier ◽  
...  
Keyword(s):  
Trace Elements ◽  
Parenteral Nutrition ◽  
Home Parenteral Nutrition ◽  
Paediatric Patients
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