An Exploratory Retrospective Study of Factors Affecting Energy Expenditure in Critically Ill Children

2019 ◽  
Vol 44 (3) ◽  
pp. 507-515
Author(s):  
Haifa Mtaweh ◽  
Christiana Garros ◽  
Allison Ashkin ◽  
Lori Tuira ◽  
Johane P. Allard ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Energy Expenditure ◽  
Critically Ill ◽  
Critically Ill Children ◽  
Factors Affecting

scholarly journals 2 Systemic glucocorticoids and bradycardia in critically ill children: a retrospective study

2020 ◽  
Vol 25 (Supplement_2) ◽  
pp. e1-e1
Author(s):  
Camille Maltais-Bilodeau ◽  
Maryse Frenette ◽  
Geneviève Morissette ◽  
Dennis Bailey ◽  
Karine Cloutier ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Heart Rate ◽  
Intensive Care ◽  
Retrospective Study ◽  
Critically Ill ◽  
Medical Staff ◽  
Pediatric Population ◽  
Critically Ill Children ◽  
Rate Variation ◽  
The Impact

Abstract Background Glucocorticoids are widely used in the pediatric population. They are associated with numerous side effects including repercussions on the cardiovascular system. The impact on heart rate is not well known, but bradycardia has been reported, mostly with high doses. Objectives We described the occurrence of bradycardias and the variation of heart rate in critically ill children receiving glucocorticoids. Design/Methods We conducted a retrospective study including 1 month old to 18 year old children admitted to the Pediatric Intensive Care Unit between 2014 and 2017, who received a glucocorticoid dose equivalent to 1 to 15 mg/kg/day of prednisone. We collected data on exposition to glucocorticoids, heart rate before, during and after the exposition, and interventions from the medical staff in response to bradycardia. The primary outcome was the occurrence of bradycardia and the secondary outcomes were the magnitude of heart rate variation and the clinical management of bradycardias. Results We included 92 admissions (85 patients). The median dose of glucocorticoid used was 2.80 mg/kg/day of prednisone (2.08—3.80). We found 70 cases (76%) with at least one bradycardia. Before treatment, all patients had a mean heart rate higher than the 5th percentile for age. During exposition to glucocorticoids, 8 patients (10%, n = 83) had a median heart rate ≤ 5th percentile. We noted 46 cases of bradycardia (50%) that led to an intervention from the medical staff, but no patient had a major event associated to bradycardia. We found a significant association between bradycardia and age (estimate -0.136, 95% CI -0.207—-0.065, p < 0.001), glucocorticoid dose (estimate 4.820, 95% CI 2.048—7.592, p < 0.001) and intravenous administration (estimate 8.709, 95% CI 1.893—15.524, p = 0.012). Conclusion In our study, most children hospitalized at the intensive care unit receiving standard doses of glucocorticoid experienced bradycardia. The majority of episodes led to an intervention from the medical staff. Presence of bradycardia was associated with younger age, higher dose and IV administration of glucocorticoids.

Can energy expenditure be predicted in critically ill children?*

2003 ◽  
Vol 4 (2) ◽  
pp. 176-180 ◽  
Author(s):  
Rachel M. Taylor ◽  
Paul Cheeseman ◽  
Victor Preedy ◽  
Alastair J. Baker ◽  
George Grimble
Keyword(s):  
Energy Expenditure ◽  
Critically Ill ◽  
Critically Ill Children

scholarly journals Serial measurements of energy expenditure in critically ill children: optimizing nutritional therapy?

Critical Care ◽  
2001 ◽  
Vol 5 (Suppl 1) ◽  
pp. P133
Author(s):  
G de Klerk ◽  
WCJ Hop ◽  
M de Hoog ◽  
KFM Joosten
Keyword(s):  
Energy Expenditure ◽  
Critically Ill ◽  
Nutritional Therapy ◽  
Critically Ill Children ◽  
Serial Measurements

scholarly journals Physical activity as a determinant of total energy expenditure in critically ill children

2007 ◽  
Vol 26 (6) ◽  
pp. 744-751 ◽  
Author(s):  
Martijn van der Kuip ◽  
Kees de Meer ◽  
Klaas R. Westerterp ◽  
Reinoud J. Gemke
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Total Energy ◽  
Critically Ill ◽  
Total Energy Expenditure ◽  
Critically Ill Children

scholarly journals Infections with Carbapenem-Resistant Gram-Negative Bacteria are a Serious Problem Among Critically Ill Children: A Single-Centre Retrospective Study

Pathogens ◽  
2019 ◽  
Vol 8 (2) ◽  
pp. 69 ◽  
Author(s):  
Fatih Aygun ◽  
Fatma Deniz Aygun ◽  
Fatih Varol ◽  
Cansu Durak ◽  
Haluk Çokuğraş ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Critically Ill ◽  
Bacterial Infections ◽  
Invasive Mechanical Ventilation ◽  
Critically Ill Children ◽  
Resistant Bacteria ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Carbapenem Resistant ◽  
Culture Positive

Children in paediatric intensive care units (PICUs) are vulnerable to infections because invasive devices are frequently used during their admission. We aimed to determine the prevalence, associated factors, and prognosis of infections in our PICU. This retrospective study evaluated culture results from 477 paediatric patients who were treated in the PICU between January 2014 and March 2019. Ninety patients (18.9%) had bacterial infections, with gram-negative bacteria being the predominant infectious agents. Culture-positive patients were younger than culture-negative patients, and age was related to mortality and various clinical factors. Culture-positive bacterial infections in the PICU were associated with increased use of invasive mechanical ventilation (odds ratio(OR); 2.254), red blood cell (RBC) transfusions (OR:2.624), and inotropic drugs (OR:2.262). Carbapenem resistance was found in approximately one-third of gram-negative bacteria, and was most common in tracheal aspirate specimens and cases involving Klebsiella spp. Total parenteral nutrition was a significant risk factor (OR:5.870). Positive blood culture results were associated with poorer patient survival than other culture results. These findings indicate that infections, especially those involving carbapenem-resistant bacteria, are an important issue when treating critically ill children.

scholarly journals Retrospective study on 48-h fluid balance and outcome in mechanically ventilated critically ill children

2020 ◽  
Vol 7 (4) ◽  
pp. 174
Author(s):  
Ramachandran Rameshkumar ◽  
Namita Ravikumar ◽  
Ponnarmeni Satheesh ◽  
Subramanian Mahadevan
Keyword(s):  
Retrospective Study ◽  
Critically Ill ◽  
Fluid Balance ◽  
Critically Ill Children ◽  
Mechanically Ventilated
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