scholarly journals A Single Urine Sodium Measurement May Validly Estimate 24‐hour Urine Sodium Excretion in Patients With an Ileostomy

2019 ◽  
Vol 44 (2) ◽  
pp. 246-255 ◽  
Author(s):  
Anne Kathrine Nissen Pedersen ◽  
Charlotte Rud ◽  
Trine Levring Wilkens ◽  
Mette Borre ◽  
Jens Rikardt Andersen ◽  
...  
Keyword(s):  
Sodium Excretion ◽  
Urine Sodium ◽  
Urine Sodium Excretion

Abstract MP78: Validity of Predictive Equations for 24-Hour Urine Sodium Excretion in Young Black and Other Adults

Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Mary Cogswell ◽  
Chia-Yih Wang ◽  
Te-Ching Chen ◽  
Christine Pfeiffer ◽  
Paul Elliott ◽  
...  
Keyword(s):  
Sodium Excretion ◽  
Sodium Intake ◽  
Urine Collection ◽  
Urine Sodium ◽  
Predictive Equations ◽  
Spot Urine ◽  
Individual Level ◽  
Urine Sodium Excretion ◽  
Mean Differences ◽  
The Individual

Introduction: Reducing mean population sodium intake by ~1200 mg is projected to reduce thousands of deaths from heart disease and stroke and save billions of health care dollars annually. Twenty-four hour urine collection is recommended for assessing changes in mean population sodium intake, but can be difficult to implement. Predicting 24-hour urine sodium excretion using spot urines is not recommended due to diurnal variations in excretion. Further, sodium excretion patterns differ between black and white persons. We assessed the validity of previously published prediction equations for 24-hour sodium excretion in black and other young adults by timing of spot urine collection. Design: Of 481 adult volunteers aged 18-39 years (50% Blacks) asked to participate in a 2011 study in the Metropolitan DC area, 407 collected each urine void in a separate container for 24 hours. Four timed voids from the 24-h urine collection were selected (morning, afternoon, evening, and overnight) to use with previously published predictive equations. Predictive equations were based on one of two approaches; 1) an indirect approach using spot urine sodium-to-creatinine concentrations and predicted 24-hour creatinine excretion ( Tanaka, Kawasaki, Mage ), and 2) a direct approach using spot urine sodium, potassium, and creatinine concentrations, and age, and body mass index with separate equations by sex ( Brown ). We assessed mean differences between predicted and measured 24-hour sodium excretion (bias) and individual differences across levels of sodium excretion using Bland-Altman plots. Results: Among participants, mean measured 24-hour sodium excretion was ~3300 mg (SD ~1400 mg). Of the equations evaluated, mean bias in predicted 24-hour sodium excretion was least from Brown equations when using morning (-165 mg, 95% confidence interval [CI], -295, -36 mg), afternoon (-90 mg, 95% CI, -208, 28 mg) or evening ( -120 mg, 95% CI -230, -11 mg) spot urines. When using overnight spot urines, mean bias from Brown equations was greatest and statistically significant (-247 mg, 95% CI, -348, -151 mg). When using overnight spot urines, mean bias from Tanaka (-23 mg) or Mage (-145 mg) equations was not significant, however, when stratified by sex, mean biases were significant and in opposite directions. Among Blacks, mean biases from Brown were not significant (-167 to 122 mg) except using overnight specimens among Black females (-267 mg, 95% CI, -525, -47 mg). Across equations and time periods, Bland-Altman plots indicated significant bias at the individual level. Conclusions: Of the evaluated equations, predicted 24-hour urine sodium excretion using the Brown equations with morning, afternoon, or evening specimens may provide the least biased estimates of group mean sodium intake among young US adults. None of the equations adequately predicted individual 24-hour sodium excretion measured on the same day.

Spot Urine Tests in Predicting 24-Hour Urine Sodium Excretion in Asian Patients

2013 ◽  
Vol 23 (6) ◽  
pp. 450-455 ◽  
Author(s):  
Srinivas Subramanian ◽  
Boon Wee Teo ◽  
Qi Chun Toh ◽  
Yun Yin Koh ◽  
Jialiang Li ◽  
...  
Keyword(s):  
Sodium Excretion ◽  
Urine Sodium ◽  
Spot Urine ◽  
Asian Patients ◽  
Urine Sodium Excretion

scholarly journals Estimated Amount of 24-Hour Urine Sodium Excretion Is Positively Correlated with Stomach and Breast Cancer Prevalence in Korea

2014 ◽  
Vol 29 (Suppl 2) ◽  
pp. S131 ◽  
Author(s):  
Jung Hwan Park ◽  
Yong Chul Kim ◽  
Ho Seok Koo ◽  
Se Won Oh ◽  
Suhnggwon Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Sodium Excretion ◽  
Urine Sodium ◽  
Cancer Prevalence ◽  
Urine Sodium Excretion

scholarly journals Variability in 24-hour urine sodium excretion in children.

Hypertension ◽  
1979 ◽  
Vol 1 (6) ◽  
pp. 631-636 ◽  
Author(s):  
K Liu ◽  
R Cooper ◽  
I Soltero ◽  
J Stamler
Keyword(s):  
Sodium Excretion ◽  
Urine Sodium ◽  
Urine Sodium Excretion

Spot urine sodium excretion as prognostic marker in acutely decompensated heart failure: the spironolactone effect

2015 ◽  
Vol 105 (6) ◽  
pp. 489-507 ◽  
Author(s):  
João Pedro Ferreira ◽  
Nicolas Girerd ◽  
Pedro Bettencourt Medeiros ◽  
Mário Santos ◽  
Henrique Cyrne Carvalho ◽  
...  
Keyword(s):  
Heart Failure ◽  
Prognostic Marker ◽  
Sodium Excretion ◽  
Decompensated Heart Failure ◽  
Urine Sodium ◽  
Spot Urine ◽  
Acutely Decompensated Heart Failure ◽  
Urine Sodium Excretion

Urine Sodium Excretion by Tolvaptan is Dependent upon Baseline Serum Sodium-Explanation for Improvement of Hyponatremia with less Hypernatremia

2013 ◽  
Vol 19 (10) ◽  
pp. S149
Author(s):  
Teruhiko Imamura ◽  
Koichiro Kinugawa ◽  
Shun Minatsuki ◽  
Hironori Muraoka ◽  
Naoko Kato ◽  
...  
Keyword(s):  
Serum Sodium ◽  
Sodium Excretion ◽  
Urine Sodium ◽  
Baseline Serum ◽  
Urine Sodium Excretion

Differential Effect of Prostaglandin A1 in Hypertensive Patients with Low, Normal and High Renin

1974 ◽  
Vol 48 (s2) ◽  
pp. 311s-313s
Author(s):  
L. R. Krakoff ◽  
N. Vlachakis ◽  
M. Mendlowitz ◽  
J. Stricker
Keyword(s):  
Arterial Pressure ◽  
Sodium Excretion ◽  
Excretion Rate ◽  
Plasma Renin ◽  
Systemic Arterial Pressure ◽  
Urine Sodium ◽  
Electrolyte Intake ◽  
Urine Sodium Excretion ◽  
Prostaglandin A1

1. Eighteen hypertensive in-patients were studied during a period of controlled electrolyte intake and, on the basis of determinations of mid-day plasma renin activity (PRA), were classified into low, normal and high renin sub-groups. 2. The responses of systemic arterial pressure, urine sodium excretion rate and PRA to infusion of prostaglandin A1 (PGA1) at a rate of 0.4 μg min−1 kg−1 for 60 min differed among the renin sub-groups. 3. The low renin sub-group displayed the greatest fall in arterial pressure and the greatest increase in sodium excretion rate during infusion of PGA1; PRA was unaffected. The normal renin group demonstrated a lesser reduction of arterial pressure and lesser rise in sodium excretion rate during infusion of PGA1 compared with the low renin group; PRA rose significantly during infusion of PGA1. No significant change in arterial pressure occurred in the high renin group during infusion of PGA1; sodium excretion rate rose less than that observed in the other two groups. Infusion of PGA1 caused striking increases in PRA in the high renin group. 4. The changes in PRA during infusion of PGA1 may explain the differences in arterial pressure and sodium excretion rate observed in the three renin sub-groups. The results also suggest that the role of the vasodilating prostaglandins may differ in the pathogenesis of low, normal and high renin hypertension.

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