scholarly journals Quantitative µMRI and PLM study of rabbit humeral and femoral head cartilage at sub‐10 µm resolutions

2019 ◽  
Vol 38 (5) ◽  
pp. 1052-1062
Author(s):  
Syeda Batool ◽  
Rohit Mahar ◽  
Farid Badar ◽  
Austin Tetmeyer ◽  
Yang Xia
Keyword(s):  
Femoral Head ◽  
Femoral Head Cartilage

scholarly journals Reliability of the classification of cartilage and labral injuries during hip arthroscopy

2020 ◽  
Vol 7 (3) ◽  
pp. 448-457
Author(s):  
Stephanie W Mayer ◽  
Tobias R Fauser ◽  
Robert G Marx ◽  
Anil S Ranawat ◽  
Bryan T Kelly ◽  
...  
Keyword(s):  
Femoral Head ◽  
Transition Zone ◽  
Central Compartment ◽  
Classification Systems ◽  
Cartilage Injury ◽  
Intraobserver Agreement ◽  
Acetabular Cartilage ◽  
Femoral Head Cartilage ◽  
Labral Tears

Abstract To determine interobserver and intraobserver reliabilities of the combination of classification systems, including the Beck and acetabular labral articular disruption (ALAD) systems for transition zone cartilage, the Outerbridge system for acetabular and femoral head cartilage, and the Beck system for labral tears. Additionally, we sought to determine interobserver and intraobserver agreements in the location of injury to labrum and cartilage. Three fellowship trained surgeons reviewed 30 standardized videos of the central compartment with one surgeon re-evaluating the videos. Labral pathology, transition zone cartilage and acetabular cartilage were classified using the Beck, Beck and ALAD systems, and Outerbridge system, respectively. The location of labral tears and transition zone cartilage injury was assessed using a clock face system, and acetabular cartilage injury using a five-zone system. Intra- and interobserver reliabilities are reported as Gwet’s agreement coefficients. Interobserver and intraobserver agreement on the location of acetabular cartilage lesions was highest in superior and anterior zones (0.814–0.914). Outerbridge interobserver and intraobserver agreement was >0.90 in most zones of the acetabular cartilage. Interobserver and intraobserver agreement on location of transition zone lesions was 0.844–0.944. The Beck and ALAD classifications showed similar interobserver and intraobserver agreement for transition zone cartilage injury. The Beck classification of labral tears was 0.745 and 0.562 for interobserver and intraobserver agreements, respectively. The Outerbridge classification had almost perfect interobserver and intraobserver agreement in classifying chondral injury of the true acetabular cartilage and femoral head. The Beck and ALAD classifications both showed moderate to substantial interobserver and intraobserver reliabilities for transition zone cartilage injury. The Beck system for classification of labral tears showed substantial agreement among observers and moderate intraobserver agreement. Interobserver agreement on location of labral tears was highest in the region where most tears occur and became lower at the anterior and posterior extents of this region. The available classification systems can be used for documentation regarding intra-articular pathology. However, continued development of a concise and highly reproducible classification system would improve communication.

scholarly journals Automatic Cartilage Segmentation for Delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Hip Joint Cartilage: A Feasibility Study

Cartilage ◽  
2018 ◽  
Vol 11 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Tobias Hesper ◽  
Bernd Bittersohl ◽  
Christoph Schleich ◽  
Harish Hosalkar ◽  
Rüdiger Krauspe ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Femoral Head ◽  
Hip Joint ◽  
Rank Correlation ◽  
Joint Cartilage ◽  
Resonance Imaging ◽  
Femoral Head Cartilage ◽  
Processing Software ◽  
Joint Assessment

Objective Automatic segmentation for biochemical cartilage evaluation holds promise for an efficient and reader-independent analysis. This pilot study aims to investigate the feasibility and to compare delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) hip joint assessment with manual segmentation of acetabular and femoral head cartilage and dGEMRIC hip joint assessment using automatic surface and volume processing software at 3 Tesla. Design Three-dimensional (3D) dGEMRIC data sets of 6 patients with hip-related pathology were assessed (1) manually including multiplanar image reformatting and regions of interest (ROI) analysis and (2) automated by using a combined surface and volume processing software. For both techniques, T1Gd values were obtained in acetabular and femoral head cartilage at 7 regions (anterior, anterior-superior, superior-anterior, superior, superior-posterior, posterior-superior, and posterior) in central and peripheral portions. Correlation between both techniques was calculated utilizing Spearman’s rank correlation coefficient. Results A high correlation between both techniques was observed for acetabular (ρ = 0.897; P < 0.001) and femoral head (ρ = 0.894; P < 0.001) cartilage in all analyzed regions of the hip joint (ρ between 0.755 and 0.955; P < 0.001). Conclusions Automatic cartilage segmentation with dGEMRIC assessment for hip joint cartilage evaluation seems feasible providing high to excellent correlation with manually performed ROI analysis. This technique is feasible for an objective, reader-independant and reliable assessment of biochemical cartilage status.

scholarly journals Cathepsin B in osteoarthritis: cytochemical and histochemical analysis of human femoral head cartilage.

1995 ◽  
Vol 54 (4) ◽  
pp. 289-297 ◽  
Author(s):  
A Baici ◽  
A Lang ◽  
D Horler ◽  
R Kissling ◽  
C Merlin
Keyword(s):  
Femoral Head ◽  
Cathepsin B ◽  
Histochemical Analysis ◽  
Femoral Head Cartilage

Femoral Head Chondrocyte Viability at the Cam Deformity in Patients With Femoroacetabular Impingement Syndrome

2020 ◽  
Vol 48 (14) ◽  
pp. 3586-3593
Author(s):  
Miranda J. Rogers ◽  
Makoto Kondo ◽  
Kyungsook Kim ◽  
Teruo Okano ◽  
Travis G. Maak
Keyword(s):  
Femoral Head ◽  
Collagen Type ◽  
Culture Period ◽  
Type I ◽  
Type Ii ◽  
Chondrocyte Viability ◽  
Cam Deformity ◽  
Immunohistochemistry Staining ◽  
Femoral Head Cartilage ◽  
The Mean

Background: Patients with hip pathology, such as femoroacetabular impingement (FAI) or hip dysplasia, are known to sustain chondral delamination injuries identifiable during hip arthroscopy, with an incidence of 44% to 75%. There are studies focused on understanding acetabular chondral flap viability, but there is a dearth of research regarding the viability of femoral head cartilage overlying the cam deformity in FAI. Purpose: To describe the viability and immunohistochemistry staining patterns of femoral head cartilage in the setting of FAI. Study Design: Descriptive laboratory study. Methods: Between September 2018 and August 2019, a single surgeon prospectively collected full-thickness femoral cartilage from cam deformities in 14 patients with FAI undergoing osteoplasty. Samples were assessed for viability and underwent immunohistochemistry staining for collagen type I, collagen type II, and aggrecan. Results: The data set included 14 patients. Twelve samples were assessed for viability and 14 for immunohistochemistry straining. The mean patient age was 34.1 years, and the mean body mass index was 24.69. Mean ± SD chondrocyte viability per patient was 52% ± 11%. At the time of cell isolation, 8 of the 12 patients had viability >50%, with a maximum of 68.2%. This viability increased after a primary culture period, varying from 9 to 13 days, with 10 of 12 samples having viability >90%. The viability mean after the culture period was 94.54% ± 4.89%. Harvested cartilage showed expressions of type I cartilage, type II collagen, and aggrecan in a pattern that is predictable for native cartilage. Conclusion: These data reveal that the cartilage in femoral head cartilage overlying cam deformity—much like that from acetabular chondral flaps—not only has baseline viability >50% (51.99% ± 10.83%) but the ability to increase in viability >90% after a culture period. There may be a role for use of femoral head cartilage as autograft to repair full-thickness cartilage defects of the acetabulum and femoral head, either at the time of osteochondroplasty or after a period of cell culture to improve cell viability. Clinical Relevance: A dearth of information is available regarding the viability of femoral head cartilage. This study provides insight into the cartilage viability and response to culture.

Calcification of the deep zone in pig femoral head cartilage

1981 ◽  
Vol 37 (12) ◽  
pp. 1333-1334 ◽  
Author(s):  
R. M. Aspden ◽  
D. W. L. Hukins
Keyword(s):  
Femoral Head ◽  
Deep Zone ◽  
Femoral Head Cartilage

scholarly journals Further studies on the composition of human femoral head cartilage.

1980 ◽  
Vol 39 (5) ◽  
pp. 514-523 ◽  
Author(s):  
A Maroudas ◽  
M T Bayliss ◽  
M F Venn
Keyword(s):  
Femoral Head ◽  
Femoral Head Cartilage

Ultrasound of femoral head cartilage: a new method of assessing bone age

1995 ◽  
Vol 24 (3) ◽  
pp. 197-200 ◽  
Author(s):  
A. Castriota-Scanderbeg ◽  
V. De Micheli
Keyword(s):  
Femoral Head ◽  
Bone Age ◽  
New Method ◽  
Femoral Head Cartilage

scholarly journals A histological and ultrastructural study of femoral head cartilage in a new type II collagenopathy

2010 ◽  
Vol 34 (8) ◽  
pp. 1333-1339 ◽  
Author(s):  
Peiqiang Su ◽  
Liangming Zhang ◽  
Yan Peng ◽  
Anjing Liang ◽  
Kaili Du ◽  
...  
Keyword(s):  
Femoral Head ◽  
Ultrastructural Study ◽  
Type Ii ◽  
Femoral Head Cartilage ◽  
New Type

scholarly journals Biochemical Changes in Tissues and Synovial Fluid of Hip Joint in Congenital and Degenerative-Dystrophic Diseases in Children and Adolescents

2016 ◽  
Vol 23 (3) ◽  
pp. 33-40
Author(s):  
O. V Kozhevnikov ◽  
S. E Kralina ◽  
L. N Furtseva ◽  
I. A Bogdanova ◽  
N. M. Savost’yanova
Keyword(s):  
Femoral Head ◽  
Synovial Fluid ◽  
Children And Adolescents ◽  
Biochemical Analysis ◽  
Hip Dislocation ◽  
Aseptic Necrosis ◽  
Tissue Samples ◽  
Femur Bone ◽  
Femoral Head Cartilage ◽  
Glycosaminoglycan Metabolism

Results of biochemical analysis of hip tissues (femoral head cartilage, proximal femur bone tissue, scarry tissue from hip cavity) and synovial fluid in 72 children and adolescents (aged 1 - 18 years) with congenital and pathologic hip dislocation, Legg-Calve-Perthes disease, femoral head aseptic necrosis and early coxarthrosis are presented. In tissue samples the content of hydroxyproline, hexuronic acids and hexoses was determined. In synovial fluid the content of hyaluronic acid, total protein and protein fractions, albumin, glucose and alkaline phosphatase activity was analyzed. It was detected that in congenital and acquired hip pathology the articular cartilage showed increased content of hydroxyproline, disorders of glycosaminoglycan metabolism and shift in glycoprotein metabolism indicative of destructive changes of basic cartilaginous tissue substance. Changes of synovial fluid chemical composition confirmed the disturbance of synovium permeability and were closely related to the clinical picture of metabolic-dystrophic changes in the joint.

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