scholarly journals Hypochlorhydria‐induced calcium malabsorption does not affect fracture healing but increases post‐traumatic bone loss in the intact skeleton

2016 ◽  
Vol 34 (11) ◽  
pp. 1914-1921 ◽  
Author(s):  
Melanie Haffner‐Luntzer ◽  
Aline Heilmann ◽  
Verena Heidler ◽  
Astrid Liedert ◽  
Thorsten Schinke ◽  
...  
Keyword(s):  
Bone Loss ◽  
Fracture Healing ◽  
Post Traumatic ◽  
Calcium Malabsorption

Treatment of post-traumatic humeral diaphyseal nonunion with bone loss

2003 ◽  
Vol 12 (5) ◽  
pp. 436-441 ◽  
Author(s):  
Christopher Pullen ◽  
Alfonso Manzotti ◽  
Maurizio A Catagni ◽  
Francesco Guerreschi
Keyword(s):  
Bone Loss ◽  
Post Traumatic

scholarly journals Calcium and vitamin-D deficiency marginally impairs fracture healing but aggravates posttraumatic bone loss in osteoporotic mice

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Verena Fischer ◽  
Melanie Haffner-Luntzer ◽  
Katja Prystaz ◽  
Annika vom Scheidt ◽  
Björn Busse ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Loss ◽  
Fracture Healing ◽  
Vitamin D Deficiency

scholarly journals Invited Review: Pathogenesis of osteoporosis

2003 ◽  
Vol 95 (5) ◽  
pp. 2142-2151 ◽  
Author(s):  
Ego Seeman
Keyword(s):  
Bone Loss ◽  
Bone Formation ◽  
Mineral Content ◽  
Fragility Fractures ◽  
Cross Sectional ◽  
Periosteal Apposition ◽  
Periosteal Surface ◽  
Architectural Decay ◽  
The Many ◽  
Calcium Malabsorption

Patients with fragility fractures may have abnormalities in bone structural and material properties such as larger or smaller bone size, fewer and thinner trabeculae, thinned and porous cortices, and tissue mineral content that is either too high or too low. Bone models and remodels throughout life; however, with advancing age, less bone is replaced than was resorbed within each remodeling site. Estrogen deficiency at menoause increases remodeling intensity: a greater proportion of bone is remodeled on its endosteal (inner) surface, and within each of the many sites even more bone is lost as more bone is resorbed while less is replaced, accelerating architectural decay. In men, there is no midlife increase in remodeling. Bone loss within each remodeling site proceeds by reduced bone formation, producing trabecular and cortical thinning. Hypogonadism in 20-30% of elderly men contributes to bone loss. In both sexes, calcium malabsorption and secondary hyperparathyroidism increase remodeling: more bone is removed from an ever-diminishing bone mass. As bone is removed from the endosteal envelope, concurrent bone formation on the periosteal (outer) bone surface during aging partly offsets bone loss and increases bone's cross-sectional area. Periosteal apposition is less in women than in men; therefore, women have more net bone loss because they gain less on the periosteal surface, not because they resorb more on the endosteal surface. More women than men experience fractures because their smaller skeleton incurs greater architectural damage and adapts less by periosteal apposition.

scholarly journals Factores de diferenciación génica y su futuro en el tratamiento de la osteoporosis: de la adipogénesis a la osteoblastogénesis, ¿del mismo modo y en sentido contrario?

2018 ◽  
Vol 5 (4) ◽  
pp. 21-25
Author(s):  
Pedro Sánchez Márquez ◽  
Carlos Arturo Révérend Lizcano
Keyword(s):  
Transcription Factor ◽  
Bone Loss ◽  
Bone Formation ◽  
Endochondral Ossification ◽  
Related Factors ◽  
Senile Osteoporosis ◽  
Age Related ◽  
Post Traumatic

El presente artículo tiene como objetivo presentar de forma resumida los diferentes factores que están involucrados en la diferenciación y el mantenimiento del fenotipo óseo, en contraste con los factores adipogénicos, cuya expresión determina procesos de diferenciación mutuamente excluyentes. Por otro lado, se propone el posible uso terapéutico para distintas patologías óseas como la osteoporosis. Los datos fueron obtenidos de estudios clínicos aleatorizados y de revisión, en idioma español e inglés, de los últimos 15 años, que incluyeran los términos Mesh: Osteoporosis; Osteoporoses; Osteoporosis, Post-Traumatic; Osteoporosis, Senile; Osteoporosis, Age-Related; Bone Loss, Age-Related; Factors, Transcription; Transcription Factor; Adipogeneses; Bone Formation; Osteoclastogenesis; Endochondral Ossification; Endochondral Ossifications; Ossification, Endochondral; Ossification, Physiological; Ossification, Physiologic.

scholarly journals No pain, no gain: Will migraine therapies increase bone loss and impair fracture healing?

EBioMedicine ◽  
2020 ◽  
Vol 60 ◽  
pp. 103025
Author(s):  
Melissa A. Kacena ◽  
Fletcher A. White
Keyword(s):  
Bone Loss ◽  
Fracture Healing

Bone Loss Following Tibial Osteotomy: A Model for Evaluating Post-traumatic Osteopenia

2000 ◽  
Vol 11 (3) ◽  
pp. 261-264 ◽  
Author(s):  
M. K. Karlsson ◽  
P.-O. Josefsson ◽  
A. Nordkvist ◽  
K. Akesson ◽  
E. Seeman ◽  
...  
Keyword(s):  
Bone Loss ◽  
Tibial Osteotomy ◽  
Post Traumatic

scholarly journals Two-stage reconstruction of post-traumatic segmental tibia bone loss with nailing

2010 ◽  
Vol 96 (5) ◽  
pp. 549-553 ◽  
Author(s):  
T. Apard ◽  
N. Bigorre ◽  
P. Cronier ◽  
F. Duteille ◽  
P. Bizot ◽  
...  
Keyword(s):  
Bone Loss ◽  
Two Stage ◽  
Tibia Bone ◽  
Post Traumatic

scholarly journals Reconstruction of Post-Traumatic Bone Loss (BL) Members: Our Experience about 27 Cases

2016 ◽  
Vol 06 (06) ◽  
pp. 139-143 ◽  
Author(s):  
Moctar Traore ◽  
Samba Kone ◽  
Maurice Kouame ◽  
Raphael Dallo Gogoua ◽  
Armand Yepie ◽  
...  
Keyword(s):  
Bone Loss ◽  
Post Traumatic
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