scholarly journals New‐onset atrial fibrillation in patients with acute coronary syndrome may be associated with worse prognosis and future heart failure

2019 ◽  
Vol 35 (2) ◽  
pp. 182-189 ◽  
Author(s):  
Mizuyoshi Nagai ◽  
Tomonori Itoh ◽  
Masaru Ishida ◽  
Tetsuya Fusazaki ◽  
Takashi Komatsu ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Coronary Syndrome ◽  
Onset Atrial Fibrillation ◽  
Worse Prognosis ◽  
New Onset

4183New onset atrial fibrillation in acute coronary syndrome: early vs late onset

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
J Alves Guimaraes ◽  
F M Goncalves ◽  
S Borges ◽  
J J Monteiro ◽  
P S Mateus ◽  
...  
Keyword(s):  
Heart Failure ◽  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Primary Endpoint ◽  
Major Bleeding ◽  
Late Onset ◽  
Prognostic Impact ◽  
Coronary Syndrome ◽  
History Of ◽  
Onset Atrial Fibrillation

Abstract Background The prognostic impact of the timing where new-onset Atrial Fibrillation (AF) occurs in Acute Coronary Syndrome (ACS) patients isn't well studied. Objective Evaluate the predictors and prognostic impact of early-onset AF (EAF) and late-onset AF (LAF) in ACS patients. Methods We analysed 17016 patients with ACS enrolled in a national multicenter registry from October 2010 to January 2019. Patients with history of valvular disease, valve replacement, AF present at hospital admission or those who died in the first 48 hours were excluded. EAF was defined as AF in the first 48 hours of hospitalization and LAF after 48 hours. The primary endpoint was a composite of death and readmission from cardiovascular causes at 1 year. Results The mean age was 65±13 years; 74% were males and 42% had STEMI). 324 (1.9%) had EAF and 344 (2.0%) had LAF. The predictors of EAF were age ≥75 years (OR 2.04, 95% CI 1.53–2.70, p<0.001); history of heart failure (OR 1.82, 95% CI 1.09–3.02, p=0.022), STEMI diagnosis (OR 2.74, 95% CI 2.06–3.61, p<0.001), admission Killip class (KK)≥2 (OR 2.70, 95% CI 1.98–3.69, p<0.001). The predictors of LAF were age ≥75 years (OR 3.15, 95% CI 2.36–4.19, p<0.001), history of stable angina (OR 1.42, 95% CI 1.06–1.90, p=0.018), cerebrovascular disease (OR 1.68, 95% CI 1.14–2.46, p=0.008), COPD (OR 2.33, 95% CI 1.58–3.44, p<0.001), STEMI diagnosis (OR 2.31, 95% CI 1.77–3.03, p<0.001), admission KK ≥2 (OR 2.06, 95% CI 1.54–2.76, p<0.001) and stress hyperglycemia (OR 1.54, 95% CI 1.15–2.05, p=0.003) In STEMI patients only those with LAF had higher symptoms time (245 (IQR 165–400) minutes vs 284 (IQR 200–425) min; p=0.02). During hospitalization, LAF patients had a worse prognosis with a higher rate of heart failure, re-infarction, stroke, major bleeding and death (Table 1). In the follow-up, in multivarite analysis, only LAF was a predictor of the primary endpoint (EAF: HR 0.79, 95% CI 0.50–1.25, p=0.314; LAF: HR 1.45, 95% CI 1.05–2.00, p<0.025). Complications during hospitalization No AF EAF LAF p Death 1.3 6.5 12.5 <0.001 Heart Failure 11.4 38.3 50.3 <0.001 Re-enfarction 1.0 0.9 3.5 <0.001 Stroke 0.5 0.9 3.8 <0.001 Major bleeding 1.3 4.3 4.1 <0.001 Kaplan Meier curve Conclusion Patients with EAF and LAF have different characteristics and outcomes with LAF patients having a worse in-hospital and long term prognosis.

scholarly journals Prognostic indicators of new onset atrial fibrillation in patients with acute coronary syndrome

2020 ◽  
Vol 43 (6) ◽  
pp. 647-651
Author(s):  
Hengliang Zhang ◽  
Pingshuan Dong ◽  
Xvming Yang ◽  
Laijing Du ◽  
Ke Wang ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Prognostic Indicators ◽  
Coronary Syndrome ◽  
Onset Atrial Fibrillation ◽  
New Onset

scholarly journals The value of syntax score to predict new‐onset atrial fibrillation in patients with acute coronary syndrome

2019 ◽  
Vol 24 (4) ◽  
Author(s):  
Omer Faruk Cirakoglu ◽  
Ahmet Oğuz Aslan ◽  
Ali Riza Akyuz ◽  
Selim Kul ◽  
Sinan Şahin ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Syntax Score ◽  
Coronary Syndrome ◽  
Onset Atrial Fibrillation ◽  
New Onset

scholarly journals P5553Predictors of new-onset atrial fibrillation after acute coronary syndrome

2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
A Marques ◽  
A C Gomes ◽  
S Alegria ◽  
A R Pereira ◽  
G Morgado ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Coronary Syndrome ◽  
Onset Atrial Fibrillation ◽  
New Onset
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