Relationship between mild traumatic brain injury and the gut microbiome: A scoping review

2021 ◽  
Author(s):  
Nozar Aghakhani
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Scoping Review ◽  
Gut Microbiome

scholarly journals Correction: Mild Traumatic Brain Injury (mTBI) and chronic cognitive impairment: A scoping review

PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0218423
Author(s):  
Kerry McInnes ◽  
Christopher L. Friesen ◽  
Diane E. MacKenzie ◽  
David A. Westwood ◽  
Shaun G. Boe
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Impairment ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Scoping Review

scholarly journals Reactive balance responses after mild traumatic brain injury (mTBI): a scoping review

2020 ◽  
Author(s):  
Amanda Morris ◽  
Tallie Casucci ◽  
Mary M. McFarland ◽  
Ben Cassidy ◽  
Ryan Pelo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Scoping Review ◽  
Quantitative Measure ◽  
Cognitive Testing ◽  
Cochrane Library ◽  
Future Research ◽  
Postural Response ◽  
Postural Responses

AbstractBackgroundBalance testing after concussion or mild traumatic brain injury (mTBI) can be useful in determining acute and chronic neuromuscular deficits that are unapparent from symptom scores or cognitive testing alone. However, current assessments of balance do not comprehensively evaluate all three classes of balance: maintaining a posture, voluntary movement, and reactive postural response. Despite the utility of reactive postural responses in predicting fall risk in other balance impaired populations, the effect of mTBI on reactive postural responses remains unclear.PurposeTo (1) examine the extent and range of available research on reactive postural responses in people post-mTBI and (2) determine if reactive postural responses (balance recovery) are affected by mTBI.Study DesignScoping review.MethodsStudies were identified using Medline, Embase, CINAHL, Cochrane Library, Dissertations and Theses Global, PsycINFO, SportDiscus, and Web of Science. Inclusion criteria were: injury classified as mTBI with no confounding central or peripheral nervous system dysfunction beyond those stemming from the mTBI, quantitative measure of reactive postural response, and a discrete, externally driven perturbation was used to test reactive postural response.ResultsA total of 4,247 publications were identified and a total of two studies (4 publications) were included in the review.ConclusionThe limited number of studies available on this topic highlight the lack of knowledge on reactive postural responses after mTBI. This review provides a new direction for balance assessments after mTBI and recommends incorporating all three classes of postural control in future research.

scholarly journals Mild Traumatic Brain Injury (mTBI) and chronic cognitive impairment: A scoping review

PLoS ONE ◽  
2017 ◽  
Vol 12 (4) ◽  
pp. e0174847 ◽  
Author(s):  
Kerry McInnes ◽  
Christopher L. Friesen ◽  
Diane E. MacKenzie ◽  
David A. Westwood ◽  
Shaun G. Boe
Keyword(s):  
Traumatic Brain Injury ◽  
Cognitive Impairment ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Scoping Review

scholarly journals A Scoping Review of Registered Clinical Studies on Mild Traumatic Brain Injury and Concussion (2000 to 2019)

Neurosurgery ◽  
2020 ◽  
Vol 87 (5) ◽  
pp. 891-899
Author(s):  
Julio C Furlan ◽  
Michael M Radan ◽  
Charles H Tator
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Scoping Review ◽  
Clinical Studies ◽  
Research Protocols ◽  
Uniform Definition ◽  
Postconcussion Symptoms ◽  
Definition Of ◽  
Research Initiatives

Abstract BACKGROUND While many patients with mild traumatic brain injury (mTBI) or concussion recover completely, prolonged postconcussion symptoms remain a challenge for patients and an opportunity for clinical research. This has led to numerous research initiatives over the last 2 decades. OBJECTIVE To review the characteristics of clinical studies on management of mTBI/concussion; and to examine their definitions of mTBI/concussion. METHODS This scoping review included all clinical studies on diagnosis and management of patients with mTBI/concussion registered at www.clinicaltrials.gov from 2000 to June/2019. The terms “mild TBI/concussion” were used for the primary search. Definitions of mTBI/concussion were obtained from the protocols. When a definition was missing in the website, the study's investigators were contacted for clarification. RESULTS There were 225 interventional and 95 observational studies. Most of the studies are focused on treatment (54.7%) or diagnosis (37.5%), while 3.4% examined preventive measures, 2.8% evaluated prognostic instruments, and 1.6% developed registries. Most of the studies in this American database were single-center initiatives led by American and Canadian institutions. The definitions of mTBI/concussion differed widely among 109 studies. CONCLUSION The results of this review suggest that most of the clinical studies are focused on diagnosis and non-pharmacological therapies for patients with mTBI/concussion. The large number of differing definitions of mTBI/concussion among the studies creates significant limitations when comparing studies. The requirements for registering research protocols on mTBI/concussion should include the necessity to state the definition being used. There is a need for consensus on a uniform definition of concussion.

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