Maternal‐fetal transmission of delta‐9‐tetrahydrocannabinol (THC) and its metabolites following inhalation and injection exposure during pregnancy in rats

2021 ◽  
Author(s):  
Samantha L. Baglot ◽  
Jonathan W. VanRyzin ◽  
Ashley E. Marquardt ◽  
Robert J. Aukema ◽  
Gavin N. Petrie ◽  
...  
Keyword(s):  
Exposure During Pregnancy ◽  
Maternal Fetal Transmission

scholarly journals Spontaneous Abortion and Chikungunya Infection: Pathological Findings

Viruses ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 554
Author(s):  
Natália Salomão ◽  
Michelle Brendolin ◽  
Kíssila Rabelo ◽  
Mayumi Wakimoto ◽  
Ana Maria de Filippis ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Spontaneous Abortion ◽  
Ultrastructural Changes ◽  
Rt Pcr ◽  
Chorionic Villi ◽  
Decidual Cells ◽  
Hofbauer Cells ◽  
Hematoxylin And Eosin ◽  
Maternal Fetal Transmission

Intrauterine transmission of the Chikungunya virus (CHIKV) during early pregnancy has rarely been reported, although vertical transmission has been observed in newborns. Here, we report four cases of spontaneous abortion in women who became infected with CHIKV between the 11th and 17th weeks of pregnancy. Laboratorial confirmation of the infection was conducted by RT-PCR on a urine sample for one case, and the other three were by detection of IgM anti-CHIKV antibodies. Hematoxylin and eosin (H&E) staining and an electron microscopy assay allowed us to find histopathological, such as inflammatory infiltrate in the decidua and chorionic villi, as well as areas of calcification, edema and the deposition of fibrinoid material, and ultrastructural changes, such as mitochondria with fewer cristae and ruptured membranes, endoplasmic reticulum with dilated cisterns, dispersed chromatin in the nuclei and the presence of an apoptotic body in case 1. In addition, by immunohistochemistry (IHC), we found a positivity for the anti-CHIKV antibody in cells of the endometrial glands, decidual cells, syncytiotrophoblasts, cytotrophoblasts, Hofbauer cells and decidual macrophages. Electron microscopy also helped in identifying virus-like particles in the aborted material with a diameter of 40–50 nm, which was consistent with the size of CHIKV particles in the literature. Our findings in this study suggest early maternal fetal transmission, adding more evidence on the role of CHIKV in fetal death.

Varicella Vaccine Exposure During Pregnancy: Data From 10 Years of the Pregnancy Registry

2008 ◽  
Vol 63 (8) ◽  
pp. 486-487 ◽  
Author(s):  
Eileen Wilson ◽  
Mary Ann Goss ◽  
Mona Marin ◽  
Kristine E. Shields ◽  
Jane F. Seward ◽  
...  
Keyword(s):  
Varicella Vaccine ◽  
Exposure During Pregnancy ◽  
Pregnancy Registry

The Importance of Mercury Speciation in the Association of Mercury Exposure During Pregnancy with Elevated Maternal Blood Pressure

Epidemiology ◽  
2009 ◽  
Vol 20 ◽  
pp. S220
Author(s):  
Ellen M Wells ◽  
Carl P Verdon ◽  
Jeff Jarrett ◽  
Kathleen L Caldwell ◽  
Frank Witter ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Maternal Blood ◽  
Mercury Exposure ◽  
Mercury Speciation ◽  
Exposure During Pregnancy ◽  
Maternal Blood Pressure

scholarly journals Association Between MRI Exposure During Pregnancy and Fetal and Childhood Outcomes

JAMA ◽  
2016 ◽  
Vol 316 (9) ◽  
pp. 952 ◽  
Author(s):  
Joel G. Ray ◽  
Marian J. Vermeulen ◽  
Aditya Bharatha ◽  
Walter J. Montanera ◽  
Alison L. Park
Keyword(s):  
Exposure During Pregnancy

scholarly journals Maternal bisphenol a exposure during pregnancy and its association with adipokines in Mexican-American children

2013 ◽  
Vol 54 (8) ◽  
pp. 621-628 ◽  
Author(s):  
Vitaly Volberg ◽  
Kim Harley ◽  
Antonia M. Calafat ◽  
Veronica Davé ◽  
Jessica McFadden ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Mexican American ◽  
Exposure During Pregnancy ◽  
American Children
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