Early administration of pyrrolidine dithiocarbamate extends the therapeutic time window of tissue plasminogen activator in a male rat model of embolic stroke

Zhongxing Wang; Weiran Shan; Jiangbei Cao; Max Wintermark; Wenqi Huang; Zhiyi Zuo

doi:10.1002/jnr.24186

Early administration of pyrrolidine dithiocarbamate extends the therapeutic time window of tissue plasminogen activator in a male rat model of embolic stroke

Journal of Neuroscience Research ◽

10.1002/jnr.24186 ◽

2017 ◽

Vol 96 (3) ◽

pp. 449-458 ◽

Cited By ~ 1

Author(s):

Zhongxing Wang ◽

Weiran Shan ◽

Jiangbei Cao ◽

Max Wintermark ◽

Wenqi Huang ◽

...

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Time Window ◽

Embolic Stroke ◽

Male Rat ◽

Pyrrolidine Dithiocarbamate ◽

Early Administration ◽

Tissue Plasminogen ◽

Therapeutic Time Window

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Opening the window: Ischemic postconditioning reduces the hyperemic response of delayed tissue plasminogen activator and extends its therapeutic time window in an embolic stroke model

European Journal of Pharmacology ◽

10.1016/j.ejphar.2015.06.043 ◽

2015 ◽

Vol 764 ◽

pp. 55-62 ◽

Cited By ~ 11

Author(s):

Ali Esmaeeli-Nadimi ◽

Derek Kennedy ◽

Mohammad Allahtavakoli

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Time Window ◽

Ischemic Postconditioning ◽

Embolic Stroke ◽

Stroke Model ◽

Tissue Plasminogen ◽

Hyperemic Response ◽

Therapeutic Time Window

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Transient brain hypothermia reduces the reperfusion injury of delayed tissue plasminogen activator and extends its therapeutic time window in a focal embolic stroke model

Brain Research Bulletin ◽

10.1016/j.brainresbull.2017.07.007 ◽

2017 ◽

Vol 134 ◽

pp. 85-90 ◽

Cited By ~ 7

Author(s):

Mohammadreza Zarisfi ◽

Fatemeh Allahtavakoli ◽

Mahsa Hassanipour ◽

Mohammad Khaksari ◽

Hossain Rezazadeh ◽

...

Keyword(s):

Reperfusion Injury ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Time Window ◽

Embolic Stroke ◽

Stroke Model ◽

Tissue Plasminogen ◽

Therapeutic Time Window

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Inhibition of PI3Kγ by AS605240 plus low-dose tissue plasminogen activator (tPA) combination improves thrombolytic therapy in a rat model of embolic stroke

Neuroscience Letters ◽

10.1016/j.neulet.2020.135339 ◽

2020 ◽

Vol 738 ◽

pp. 135339

Author(s):

Rong Jin ◽

Wei Zhong ◽

Shan Liu ◽

Min Wang ◽

Guohong Li

Keyword(s):

Thrombolytic Therapy ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Low Dose ◽

Embolic Stroke ◽

Tissue Plasminogen

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A Combined Treatment With Tacrolimus (FK506) and Recombinant Tissue Plasminogen Activator for Thrombotic Focal Cerebral Ischemia in Rats: Increased Neuroprotective Efficacy and Extended Therapeutic Time Window

Journal of Cerebral Blood Flow & Metabolism ◽

10.1097/00004647-200210000-00008 ◽

2002 ◽

pp. 1205-1211 ◽

Cited By ~ 19

Author(s):

Masashi Maeda ◽

Yasuhisa Furuichi ◽

Noriko Ueyama ◽

Akira Moriguchi ◽

Natsuki Satoh ◽

...

Keyword(s):

Cerebral Ischemia ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Time Window ◽

Focal Cerebral Ischemia ◽

Combined Treatment ◽

Recombinant Tissue Plasminogen Activator ◽

Tissue Plasminogen ◽

Neuroprotective Efficacy ◽

Therapeutic Time Window

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Extension of the Therapeutic Window for Recombinant Tissue Plasminogen Activator With Argatroban in a Rat Model of Embolic Stroke

Stroke ◽

10.1161/hs1101.097390 ◽

2001 ◽

Vol 32 (11) ◽

pp. 2635-2640 ◽

Cited By ~ 37

Author(s):

D. C. Morris ◽

L. Zhang ◽

Z. G. Zhang ◽

M. Lu ◽

K. L. Berens ◽

...

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Recombinant Tissue Plasminogen Activator ◽

Embolic Stroke ◽

Therapeutic Window ◽

Tissue Plasminogen

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Adjuvant Treatment With a Glycoprotein IIb/IIIa Receptor Inhibitor Increases the Therapeutic Window for Low-Dose Tissue Plasminogen Activator Administration in a Rat Model of Embolic Stroke

Circulation ◽

10.1161/01.cir.0000068374.57764.eb ◽

2003 ◽

Vol 107 (22) ◽

pp. 2837-2843 ◽

Cited By ~ 56

Author(s):

Li Zhang ◽

Zheng Gang Zhang ◽

Ruilan Zhang ◽

Daniel Morris ◽

Mei Lu ◽

...

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Adjuvant Treatment ◽

Rat Model ◽

Low Dose ◽

Embolic Stroke ◽

Therapeutic Window ◽

Tissue Plasminogen ◽

Receptor Inhibitor

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Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: Comparison with tissue plasminogen activator

Experimental Neurology ◽

10.1016/j.expneurol.2006.10.003 ◽

2007 ◽

Vol 204 (1) ◽

pp. 138-146 ◽

Cited By ~ 21

Author(s):

Yasuhisa Furuichi ◽

Masashi Maeda ◽

Nobuya Matsuoka ◽

Seitaro Mutoh ◽

Takehiko Yanagihara

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Nonhuman Primate ◽

Model Comparison ◽

Time Window ◽

Stroke Model ◽

Tissue Plasminogen ◽

Therapeutic Time Window

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Effects of ML351 and tissue plasminogen activator combination therapy in a rat model of focal embolic stroke

Journal of Neurochemistry ◽

10.1111/jnc.15308 ◽

2021 ◽

Author(s):

Guangsen Cheng ◽

Wei Zhao ◽

Yongjie Xin ◽

Guomin Huang ◽

Yongkang Liu ◽

...

Keyword(s):

Combination Therapy ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Embolic Stroke ◽

Tissue Plasminogen

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Interrelations between blood-brain barrier permeability and matrix metalloproteinases are differently affected by tissue plasminogen activator and hyperoxia in a rat model of embolic stroke

Medical Gas Research ◽

10.1186/2045-9912-2-2 ◽

2012 ◽

Vol 2 (1) ◽

pp. 2 ◽

Cited By ~ 8

Author(s):

Dominik Michalski ◽

Carsten Hobohm ◽

Christopher Weise ◽

Johann Pelz ◽

Marita Heindl ◽

...

Keyword(s):

Matrix Metalloproteinases ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Blood Brain Barrier ◽

Rat Model ◽

Embolic Stroke ◽

Barrier Permeability ◽

Blood Brain Barrier Permeability ◽

Brain Barrier Permeability ◽

Tissue Plasminogen

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Serum S100B indicates successful combination treatment with recombinant tissue plasminogen activator and MK-801 in a rat model of embolic stroke

Brain Research ◽

10.1016/j.brainres.2007.03.085 ◽

2007 ◽

Vol 1154 ◽

pp. 194-199 ◽

Cited By ~ 12

Author(s):

Yu Tanaka ◽

Toshiyuki Marumo ◽

Tomohiro Omura ◽

Shigeru Yoshida

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Rat Model ◽

Combination Treatment ◽

Recombinant Tissue Plasminogen Activator ◽

Embolic Stroke ◽

Serum S100b ◽

Mk 801 ◽

Tissue Plasminogen

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