scholarly journals Sex differences in the functional lateralization of emotion and decision making in the human brain

2016 ◽  
Vol 95 (1-2) ◽  
pp. 270-278 ◽  
Author(s):  
Justin Reber ◽  
Daniel Tranel
Keyword(s):  
Decision Making ◽  
Sex Differences ◽  
Human Brain ◽  
Functional Lateralization

scholarly journals Risk-based Decision Making in Rats: Modulation by Sex and Amphetamine

2020 ◽  
Author(s):  
Dannia Islas-Preciado ◽  
Steven R. Wainwright ◽  
Julia Sniegocki ◽  
Stephane E. Lieblich ◽  
Shunya Yagi ◽  
...  
Keyword(s):  
Decision Making ◽  
Sex Differences ◽  
Gonadal Hormones ◽  
Risky Choice ◽  
Female Rats ◽  
Male Rats ◽  
Risky Decision Making ◽  
Risky Decision ◽  
17Β Estradiol ◽  
Males And Females

AbstractDecision-making is a complex process essential to daily adaptation in many species. Risk is an inherent aspect of decision-making and it is influenced by gonadal hormones. Testosterone and 17β-estradiol may modulate decision making and impact the mesocorticolimbic dopamine pathway. Here, we explored sex differences, the effect of gonadal hormones and the dopamine agonist amphetamine on risk-based decision making. Intact or gonadectomised (GDX) male and female rats underwent to a probabilistic discounting task. High and low doses of testosterone propionate (1.0 or 0.2 mg) and 17β-estradiol benzoate (0.3 μg) were administered to assess acute effects on risk-based decision making. After 3-days of washout period, intact and GDX rats received high or low (0.5 or 0.125 mg/kg) doses of amphetamine and re-tested in the probabilistic discounting task. Under baseline conditions, males made more risky choices during probability discounting compared to female rats, particularly in the lower probability blocks, but GDX did not influence risky choice. The high, but not the low dose, of testosterone modestly reduced risky decision making in GDX male rats. Conversely, 17β-estradiol had no significant effect on risky choice regardless of GDX status in either sex. Lastly, a higher dose of amphetamine increased risky decision making in both intact males and females, but had no effect in GDX rats. These findings demonstrated sex differences in risk-based decision making, with males showing a stronger bias towards larger, uncertain rewards. GDX status influenced the effects of amphetamine, suggesting different dopaminergic regulation in risk-based choices among males and females.

Development of sex differences in the human brain

2020 ◽  
pp. 1-8
Author(s):  
Florian Kurth ◽  
Christian Gaser ◽  
Eileen Luders
Keyword(s):  
Sex Differences ◽  
Human Brain

Regional sex differences in grey matter volume are associated with sex hormones in the young adult human brain

NeuroImage ◽  
2010 ◽  
Vol 49 (2) ◽  
pp. 1205-1212 ◽  
Author(s):  
A. Veronica Witte ◽  
Markus Savli ◽  
Alexander Holik ◽  
Siegfried Kasper ◽  
Rupert Lanzenberger
Keyword(s):  
Sex Differences ◽  
Young Adult ◽  
Human Brain ◽  
Sex Hormones ◽  
Grey Matter ◽  
Grey Matter Volume ◽  
Adult Human Brain ◽  
Matter Volume ◽  
Adult Human

scholarly journals Country and Sex Differences in Decision Making Under Uncertainty and Risk

2020 ◽  
Vol 11 ◽  
Author(s):  
Varsha Singh ◽  
Johannes Schiebener ◽  
Silke M. Müller ◽  
Magnus Liebherr ◽  
Matthias Brand ◽  
...  
Keyword(s):  
Decision Making ◽  
Sex Differences ◽  
Decision Making Under Uncertainty

scholarly journals Preliminary Evidence for a Sex-Specific Relationship between Amount of Cannabis Use and Neurocognitive Performance in Young Adult Cannabis Users

2013 ◽  
Vol 19 (9) ◽  
pp. 1009-1015 ◽  
Author(s):  
Natania A. Crane ◽  
Randi Melissa Schuster ◽  
Raul Gonzalez
Keyword(s):  
Decision Making ◽  
Sex Differences ◽  
Young Adult ◽  
Episodic Memory ◽  
Memory Performance ◽  
Cannabis Use ◽  
Neurocognitive Deficits ◽  
Neurocognitive Performance ◽  
Preclinical Research ◽  
The Impact

AbstractAccumulating evidence suggests neuropsychological deficits from cannabis use, with a burgeoning area of preclinical research indicating possible sex-differences. However, few studies have examined how cannabis use may differentially impact neurocognition in male and female cannabis users. As such, we examined potential sex-differences in associations between amount of cannabis use (across several time frames) and neurocognitive performance among young adult regular cannabis users. Consistent with previous studies, more cannabis use was generally associated with poorer episodic memory and decision-making, but not other measures of inhibitory control. However, patterns of results suggested sex-specific dissociations. In particular, more cannabis use was more consistently associated with poorer episodic memory performance in females than males. Conversely, more cannabis use was associated with poorer decision-making performance for males, but not females. These results provide further evidence for residual cannabis-associated neurocognitive deficits and suggest the importance of examining the impact of cannabis on neurocognition separately for males and females. (JINS, 2013, 19, 1–7)

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