Excitatory effect of norepinephrine on neurons in the inferior vestibular nucleus and the underlying receptor mechanism

2016 ◽  
Vol 94 (8) ◽  
pp. 736-748 ◽  
Author(s):  
Shi-Yu Peng ◽  
Qian-Xing Zhuang ◽  
Yong-Xiao Zhang ◽  
Xiao-Yang Zhang ◽  
Jian-Jun Wang ◽  
...  
Keyword(s):  
Vestibular Nucleus ◽  
Excitatory Effect ◽  
Inferior Vestibular Nucleus

Histamine excites neurons of the inferior vestibular nucleus in rats by activation of H1 and H2 receptors

2013 ◽  
Vol 541 ◽  
pp. 87-92 ◽  
Author(s):  
Shi-Yu Peng ◽  
Qian-Xing Zhuang ◽  
Ye-Cheng He ◽  
Jing-Ning Zhu ◽  
Jian-Jun Wang
Keyword(s):  
Vestibular Nucleus ◽  
H2 Receptors ◽  
Inferior Vestibular Nucleus

Medullary Astrogliosis in Sudden Infant Death Syndrome Varies With Sleeping Environment: Evidence for Different Mechanisms of Death in Alone Versus Co-sleepers?

2018 ◽  
Vol 33 (4) ◽  
pp. 269-274 ◽  
Author(s):  
Jade Spinelli ◽  
Roger W. Byard ◽  
Corinna Van Den Heuvel ◽  
Lyndsey E. Collins-Praino
Keyword(s):  
Glial Fibrillary Acidic Protein ◽  
Sudden Infant Death Syndrome ◽  
Infant Death ◽  
Time Course ◽  
Vestibular Nucleus ◽  
Sudden Infant Death ◽  
Acidic Protein ◽  
Medial Vestibular Nucleus ◽  
Sudden Infant ◽  
Inferior Vestibular Nucleus

Sudden infant death syndrome remains the leading cause of death in infants under 1 year, and underlying pathophysiological mechanisms are poorly understood. The current study investigated the hypothesis that co-sleepers die more rapidly from causes such as suffocation from overlaying by comparing levels of reactive astrogliosis in the medulla of infants who died sleeping alone to those who died co-sleeping. The amount of glial fibrillary acidic protein (GFAP) staining in alone sleepers was significantly higher than shared sleepers in 3 specific areas of the medulla, the inferior vestibular nucleus, the medial vestibular nucleus and the cochlear nucleus. Given that glial fibrillary acidic protein elevations follow a delayed time course, this suggests that death in co-sleepers was more rapid, not allowing for reactive gliosis to occur. This provides evidence of pathological differences in mechanisms of death in infants who are classified as having died from sudden infant death syndrome, suggesting potential need for refinement of categorization of these cases.

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