3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through α7 nicotinic acetylcholine receptor stimulation in rats

Syuuichirou Suzuki; Jun Kawamata; Takashi Matsushita; Akihiro Matsumura; Shin Hisahara; Kazuyuki Takata; Yoshihisa Kitamura; William Kem; Shun Shimohama

doi:10.1002/jnr.23160

3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through α7 nicotinic acetylcholine receptor stimulation in rats

Journal of Neuroscience Research ◽

10.1002/jnr.23160 ◽

2012 ◽

Vol 91 (3) ◽

pp. 462-471 ◽

Cited By ~ 35

Author(s):

Syuuichirou Suzuki ◽

Jun Kawamata ◽

Takashi Matsushita ◽

Akihiro Matsumura ◽

Shin Hisahara ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Stimulation ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

6 Hydroxydopamine ◽

Benzylidene Anabaseine

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α7 Nicotinic Acetylcholine Receptor Stimulation Inhibits Lipopolysaccharide-Induced Interleukin-18 and -12 Production in Monocytes

Journal of Pharmacological Sciences ◽

10.1254/jphs.sc0060074 ◽

2006 ◽

Vol 102 (1) ◽

pp. 143-146 ◽

Cited By ~ 18

Author(s):

Hideo Kohka Takahashi ◽

Hiromi Iwagaki ◽

Ryosuke Hamano ◽

Tadashi Yoshino ◽

Noriaki Tanaka ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Interleukin 18 ◽

Receptor Stimulation ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): Application to the design of related α7 selective ligands

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2011.09.033 ◽

2011 ◽

Vol 46 (11) ◽

pp. 5625-5635 ◽

Cited By ~ 12

Author(s):

David C. Kombo ◽

Anatoly Mazurov ◽

Kartik Tallapragada ◽

Philip S. Hammond ◽

Joseph Chewning ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Binding Proteins ◽

Docking Studies ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Selective Ligands ◽

Acetylcholine Binding Proteins ◽

Benzylidene Anabaseine

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Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2011.11.090 ◽

2012 ◽

Vol 22 (2) ◽

pp. 1179-1186 ◽

Cited By ~ 12

Author(s):

David C. Kombo ◽

Anatoly A. Mazurov ◽

Joseph Chewning ◽

Philip S. Hammond ◽

Kartik Tallapragada ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Docking Studies ◽

Receptor Ligands ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Benzylidene Anabaseine

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Activation of α7 nicotinic acetylcholine receptor alleviates cerebral cortical neuron injury induced by oxygen-glucose deprivation

Academic Journal of Second Military Medical University ◽

10.3724/sp.j.1008.2015.00472 ◽

2015 ◽

Vol 36 (5) ◽

pp. 472

Author(s):

Ru-juan XIN ◽

Ting ZHAO ◽

Min NI ◽

Dong-jie LI ◽

Fu-ming SHEN

Keyword(s):

Cortical Neuron ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Glucose Deprivation ◽

Oxygen Glucose Deprivation ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Cerebral Cortical Neuron ◽

Neuron Injury

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Discovery of novel positive allosteric modulators of the α7 nicotinic acetylcholine receptor: Scaffold hopping approach

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113189 ◽

2021 ◽

Vol 214 ◽

pp. 113189

Author(s):

István Ledneczki ◽

Pál Tapolcsányi ◽

Eszter Gábor ◽

András Visegrády ◽

Márton Vass ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Allosteric Modulators ◽

Scaffold Hopping ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Positive Allosteric Modulators

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Retracted : Role of α7‐nicotinic acetylcholine receptor in human non‐small cell lung cancer proliferation

Cell Proliferation ◽

10.1111/j.1365-2184.2008.00566.x ◽

2008 ◽

Vol 41 (6) ◽

pp. 936-959 ◽

Cited By ~ 57

Author(s):

L. Paleari ◽

A. Catassi ◽

M. Ciarlo ◽

Z. Cavalieri ◽

C. Bruzzo ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Cancer Proliferation ◽

Nicotinic Acetylcholine

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Nicotine Accelerates Atherosclerosis in Apolipoprotein E–Deficient Mice by Activating α7 Nicotinic Acetylcholine Receptor on Mast Cells

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.116.307264 ◽

2017 ◽

Vol 37 (1) ◽

pp. 53-65 ◽

Cited By ~ 27

Author(s):

Chen Wang ◽

Han Chen ◽

Wei Zhu ◽

Yinchuan Xu ◽

Mingfei Liu ◽

...

Keyword(s):

Mast Cells ◽

Apolipoprotein E ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Deficient Mice

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Serotonin antagonizes the human neuronal α7 nicotinic acetylcholine receptor and becomes an agonist after L248T α7 mutation

Neuroscience ◽

10.1016/s0306-4522(01)00567-x ◽

2002 ◽

Vol 110 (1) ◽

pp. 169-179 ◽

Cited By ~ 14

Author(s):

S Fucile ◽

E Palma ◽

F Eusebi ◽

R Miledi

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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Nicotine increases eclampsia-like seizure threshold and attenuates microglial activity in rat hippocampus through the α7 nicotinic acetylcholine receptor

Brain Research ◽

10.1016/j.brainres.2016.04.043 ◽

2016 ◽

Vol 1642 ◽

pp. 487-496 ◽

Cited By ~ 18

Author(s):

Xiaolan Li ◽

Xinjia Han ◽

Junjie Bao ◽

Yuanyuan Liu ◽

Aihua Ye ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Rat Hippocampus ◽

Seizure Threshold ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine

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Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal

Psychopharmacology ◽

10.1007/s00213-018-4879-7 ◽

2018 ◽

Vol 235 (7) ◽

pp. 1897-1905 ◽

Cited By ~ 10

Author(s):

Asti Jackson ◽

Roger L. Papke ◽

M. Imad Damaj

Keyword(s):

Mouse Model ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotine Withdrawal ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Pharmacological Modulation

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