Differential effects of the HESR/HEY transcription factor family on dopamine transporter reporter gene expression via variable number of tandem repeats

2011 ◽  
Vol 89 (4) ◽  
pp. 562-575 ◽  
Author(s):  
Kouta Kanno ◽  
Shoichi Ishiura
2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Uwe Töpfer ◽  
Maik C. Bischoff ◽  
Marek Bartkuhn ◽  
Anne Holz

Abstract Transcriptional regulation of Laminin expression during embryogenesis is a key step required for proper ECM assembly. We show, that in Drosophila the Laminin B1 and Laminin B2 genes share expression patterns in mesodermal cells as well as in endodermal and ectodermal gut primordia, yolk and amnioserosa. In the absence of the GATA transcription factor Serpent, the spatial extend of Laminin reporter gene expression was strongly limited, indicating that Laminin expression in many tissues depends on Serpent activity. We demonstrate a direct binding of Serpent to the intronic enhancers of Laminin B1 and Laminin B2. In addition, ectopically expressed Serpent activated enhancer elements of Laminin B1 and Laminin B2. Our results reveal Serpent as an important regulator of Laminin expression across tissues.


1993 ◽  
Vol 156 (2) ◽  
pp. 552-556 ◽  
Author(s):  
Prahlad T. Ram ◽  
Richard M. Schultz

1996 ◽  
Vol 30 (1) ◽  
pp. 199-205 ◽  
Author(s):  
Mathias Zeidler ◽  
Christiane Gatz ◽  
Elmar Hartmann ◽  
Jon Hughes

1995 ◽  
Vol 29 (6) ◽  
pp. 1293-1298 ◽  
Author(s):  
Uwe K�hler ◽  
Marie-Fran�oise Liaud ◽  
Ralf R. Mendel ◽  
R�diger Cerff ◽  
Reinhard Hehl

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