Impairment of nuclear factor-κB activation increased glutamate excitotoxicity in a motoneuron-neuroblastoma hybrid cell line expressing mutant (G93A) Cu/Zn-superoxide dismutase

2010 ◽  
pp. NA-NA
Author(s):  
Jung-Soo Pyo ◽  
Young San Ko ◽  
Woo Ho Kim ◽  
Manho Kim ◽  
Kwang-Woo Lee ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Cell Line ◽  
Hybrid Cell ◽  
Nuclear Factor Κb ◽  
Hybrid Cell Line ◽  
Glutamate Excitotoxicity ◽  
Nuclear Factor

Acetaminophen down-regulates interleukin-1β-induced nuclear factor-κB nuclear translocation in a human astrocytic cell line

2003 ◽  
Vol 353 (2) ◽  
pp. 79-82 ◽  
Author(s):  
Francesca Mancini ◽  
Carla Landolfi ◽  
Marta Muzio ◽  
Luciano Aquilini ◽  
Lucia Soldo ◽  
...  
Keyword(s):  
Cell Line ◽  
Nuclear Translocation ◽  
Nuclear Factor Κb ◽  
Interleukin 1Β ◽  
Nuclear Factor

scholarly journals Involvement of cofilin phosphorylation in neuritogenesis in a neuroblastoma x glioma hybrid cell line

2001 ◽  
Vol 41 (supplement) ◽  
pp. S139
Author(s):  
T Tojima ◽  
M Takahashi ◽  
T Obinata ◽  
E Ito
Keyword(s):  
Cell Line ◽  
Hybrid Cell ◽  
Hybrid Cell Line ◽  
Cofilin Phosphorylation ◽  
Glioma Hybrid Cell

scholarly journals Fibrinolytic properties of a human endothelial hybrid cell line (Ea.hy 926)

Blood ◽  
1988 ◽  
Vol 71 (6) ◽  
pp. 1669-1675 ◽  
Author(s):  
JJ Emeis ◽  
CJ Edgell
Keyword(s):  
Cell Line ◽  
Plasminogen Activator ◽  
Hybrid Cell ◽  
Plasminogen Activator Inhibitor ◽  
Conditioned Media ◽  
Hybrid Cell Line ◽  
Tissue Type ◽  
Human Carcinoma ◽  
Microtubule Inhibitors ◽  
Activator Inhibitor

Abstract The fibrinolytic characteristics of the endothelial hybrid cell line EA.hy 926, established by fusing a human umbilical vein endothelial cell with a human carcinoma cell line, were studied. The hybrid cell line produced large amounts of tissue-type plasminogen activator (t- PA), plasminogen activator inhibitor type 1, and a small amount of urokinase. All plasminogen activator present in conditioned medium was complexed with inhibitor because the cells secreted plasminogen activator inhibitor in excess over plasminogen activator and no activator activity was detectable in conditioned media by direct activity assays. t-PA activator activity was, however, demonstrable in conditioned media after treatment with sodium dodecyl sulfate, in agreement with t-PA antigen determinations. Increased plasminogen activator inhibitor activity could be induced by incubating the cells in the presence of endotoxin or microtubule inhibitors, whereas increased t-PA activity could be induced by microtubule inhibitors. Interleukin-1 had no effect. The fibrinolytic characteristics of the hybrid cell line were stable for at least 30 passages. The perpetual human hybrid cell line EA.hy 926 therefore may be a useful tool for the study of fibrinolysis in cultured endothelial cells.

scholarly journals Growth Hormone Prevents Apoptosis through Activation of Nuclear Factor-κB in Interleukin-3-Dependent Ba/F3 Cell Line

2000 ◽  
Vol 14 (5) ◽  
pp. 650-661 ◽  
Author(s):  
Sébastien Jeay ◽  
Gail E. Sonenshein ◽  
Marie-Catherine Postel-Vinay ◽  
Elena Baixeras
Keyword(s):  
Growth Hormone ◽  
Cell Line ◽  
Nuclear Factor Κb ◽  
Nuclear Factor ◽  
Interleukin 3

Morphine elevates levels of cyclic GMP in a neuroblastoma X glioma hybrid cell line

Nature ◽  
1975 ◽  
Vol 256 (5512) ◽  
pp. 57-59 ◽  
Author(s):  
ROBERT GULLIS ◽  
JÖRG TRABER ◽  
BERND HAMPRECHT
Keyword(s):  
Cell Line ◽  
Cyclic Gmp ◽  
Hybrid Cell ◽  
Hybrid Cell Line ◽  
Glioma Hybrid Cell
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