Gene transfer of glial cell-derived neurotrophic factor and cardiotrophin-1 protects PC12 cells from injury: Involvement of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase pathways

Gabor Toth; Huibin Yang; Roumen A. Anguelov; Jason Vettraino; Yuying Wang; Gyula Acsadi

doi:10.1002/jnr.10358

Gene transfer of glial cell-derived neurotrophic factor and cardiotrophin-1 protects PC12 cells from injury: Involvement of the phosphatidylinositol 3-kinase and mitogen-activated protein kinase kinase pathways

Journal of Neuroscience Research ◽

10.1002/jnr.10358 ◽

2002 ◽

Vol 69 (5) ◽

pp. 622-632 ◽

Cited By ~ 14

Author(s):

Gabor Toth ◽

Huibin Yang ◽

Roumen A. Anguelov ◽

Jason Vettraino ◽

Yuying Wang ◽

...

Keyword(s):

Protein Kinase ◽

Gene Transfer ◽

Pc12 Cells ◽

Glial Cell ◽

Neurotrophic Factor ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Mitogen Activated Protein ◽

Protein Kinase Kinase ◽

Phosphatidylinositol 3

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Glial cell line-derived neurotrophic factor promotes survival and induces differentiation through the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathway respectively in PC12 cells

Neuroscience ◽

10.1016/s0306-4522(01)00093-8 ◽

2001 ◽

Vol 104 (2) ◽

pp. 593-598 ◽

Cited By ~ 28

Author(s):

Z.-Y Chen ◽

Y.-F Chai ◽

L Cao ◽

A.-J Huang ◽

R.-Y Cui ◽

...

Keyword(s):

Protein Kinase ◽

Cell Line ◽

Pc12 Cells ◽

Glial Cell ◽

Neurotrophic Factor ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Mitogen Activated Protein ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Simultaneous inhibition of the mitogen-activated protein kinase kinase and phosphatidylinositol 3'-kinase pathways enhances sensitivity to paclitaxel in ovarian carcinoma

Cancer Science ◽

10.1111/j.1349-7006.2007.00624.x ◽

2007 ◽

Vol 98 (12) ◽

pp. 2002-2008 ◽

Cited By ~ 10

Author(s):

Wakae Kawaguchi ◽

Hiroaki Itamochi ◽

Junzo Kigawa ◽

Yasunobu Kanamori ◽

Tetsuro Oishi ◽

...

Keyword(s):

Protein Kinase ◽

Ovarian Carcinoma ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Mitogen Activated Protein ◽

Simultaneous Inhibition ◽

Protein Kinase Kinase ◽

Phosphatidylinositol 3

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Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-06-0269 ◽

2006 ◽

Vol 5 (12) ◽

pp. 3071-3077 ◽

Cited By ~ 46

Author(s):

Barbara Bedogni ◽

Scott M. Welford ◽

Andrea C. Kwan ◽

James Ranger-Moore ◽

Kathylynn Saboda ◽

...

Keyword(s):

Protein Kinase ◽

Mouse Model ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Mitogen Activated Protein ◽

Protein Kinase Kinase ◽

Phosphatidylinositol 3

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Semaphorin 3F Antagonizes Neurotrophin-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase Kinase Signaling: A Mechanism for Growth Cone Collapse

Journal of Neuroscience ◽

10.1523/jneurosci.23-20-07602.2003 ◽

2003 ◽

Vol 23 (20) ◽

pp. 7602-7609 ◽

Cited By ~ 74

Author(s):

Jasvinder K. Atwal ◽

Karun K. Singh ◽

Marc Tessier-Lavigne ◽

Freda D. Miller ◽

David R. Kaplan

Keyword(s):

Protein Kinase ◽

Growth Cone ◽

Mitogen Activated Protein Kinase ◽

Kinase Signaling ◽

Phosphatidylinositol 3 Kinase ◽

Growth Cone Collapse ◽

Semaphorin 3F ◽

Mitogen Activated Protein ◽

Protein Kinase Kinase ◽

Phosphatidylinositol 3

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Differential involvement of phosphatidylinositol 3-kinase and p42/p44 mitogen activated protein kinase pathways in brain-derived neurotrophic factor-induced trophic effects on cultured striatal neurons

Molecular and Cellular Neuroscience ◽

10.1016/j.mcn.2003.11.012 ◽

2004 ◽

Vol 25 (3) ◽

pp. 460-468 ◽

Cited By ~ 21

Author(s):

Núria Gavaldà ◽

Esther Pérez-Navarro ◽

Elena Gratacòs ◽

Joan X Comella ◽

Jordi Alberch

Keyword(s):

Protein Kinase ◽

Neurotrophic Factor ◽

Brain Derived Neurotrophic Factor ◽

Mitogen Activated Protein Kinase ◽

Striatal Neurons ◽

Phosphatidylinositol 3 Kinase ◽

Trophic Effects ◽

Mitogen Activated Protein ◽

Differential Involvement ◽

Phosphatidylinositol 3

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Inhibition of Phosphatidylinositol 3-Kinase or Mitogen-Activated Protein Kinase Kinase Leads to Suppression of p34cdc2 Kinase Activity and Meiotic Progression Beyond the Meiosis I Stage in Porcine Oocytes Surrounded with Cumulus Cells

Biology of Reproduction ◽

10.1095/biolreprod65.2.442 ◽

2001 ◽

Vol 65 (2) ◽

pp. 442-448 ◽

Cited By ~ 22

Author(s):

Masayuki Shimada ◽

Wen-Xian Zeng ◽

Takato Terada

Keyword(s):

Protein Kinase ◽

Kinase Activity ◽

Cumulus Cells ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Meiotic Progression ◽

Mitogen Activated Protein ◽

Meiosis I ◽

Protein Kinase Kinase ◽

Phosphatidylinositol 3

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Topical Treatment with Inhibitors of the Phosphatidylinositol 3′-Kinase/Akt and Raf/Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Pathways Reduces Melanoma Development in Severe Combined Immunodeficient Mice

Cancer Research ◽

10.1158/0008-5472.can-03-3327 ◽

2004 ◽

Vol 64 (7) ◽

pp. 2552-2560 ◽

Cited By ~ 54

Author(s):

Barbara Bedogni ◽

Melony S. O’Neill ◽

Scott M. Welford ◽

Donna M. Bouley ◽

Amato J. Giaccia ◽

...

Keyword(s):

Protein Kinase ◽

Topical Treatment ◽

Mitogen Activated Protein Kinase ◽

Phosphatidylinositol 3 Kinase ◽

Immunodeficient Mice ◽

Extracellular Signal Regulated Kinase ◽

Extracellular Signal ◽

Mitogen Activated Protein ◽

Protein Kinase Kinase ◽

Phosphatidylinositol 3

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Glial cell line-derived neurotrophic factor promotes the arborization of cultured striatal neurons through the p42/p44 mitogen-activated protein kinase pathway

Journal of Neuroscience Research ◽

10.1002/jnr.20713 ◽

2006 ◽

Vol 83 (1) ◽

pp. 68-79 ◽

Cited By ~ 15

Author(s):

Juan M. García-Martínez ◽

Esther Pérez-Navarro ◽

Núria Gavaldà ◽

Jordi Alberch

Keyword(s):

Protein Kinase ◽

Cell Line ◽

Glial Cell ◽

Neurotrophic Factor ◽

Mitogen Activated Protein Kinase ◽

Striatal Neurons ◽

Mitogen Activated Protein ◽

Kinase Pathway

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In vivo gene transfer: prevention of neointima formation by inhibition of mitogen-activated protein kinase kinase

Basic Research in Cardiology ◽

10.1007/bf00796211 ◽

1997 ◽

Vol 92 (6) ◽

pp. 378-384 ◽

Cited By ~ 19

Author(s):

C. Indolfi ◽

E. V. Avvedimento ◽

A. Rapacciuolo ◽

G. Esposito ◽

E. Lorenzo ◽

...

Keyword(s):

Protein Kinase ◽

Gene Transfer ◽

Mitogen Activated Protein Kinase ◽

Neointima Formation ◽

Mitogen Activated Protein ◽

In Vivo Gene Transfer ◽

Protein Kinase Kinase

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Clinical Validation of Coexisting Activating Mutations Within EGFR, Mitogen-Activated Protein Kinase, and Phosphatidylinositol 3-Kinase Pathways in Lung Cancers

Archives of Pathology & Laboratory Medicine ◽

10.5858/arpa.2017-0495-oa ◽

2019 ◽

Vol 143 (2) ◽

pp. 174-182 ◽

Cited By ~ 6

Author(s):

Federico De Marchi ◽

Lisa Haley ◽

Henderson Fryer ◽

Junaid Ibrahim ◽

Katie Beierl ◽

...

Keyword(s):

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Clinical Validation ◽

Phosphatidylinositol 3 Kinase ◽

Lung Cancers ◽

Activating Mutations ◽

Mitogen Activated Protein ◽

Phosphatidylinositol 3

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