scholarly journals “Angiotensin‐Converting‐Enzyme Insertion/Deletion ( I/D ) polymorphism, ACE activity and COVID‐19: a rather controversial hypothesis. A case – control study”

2021 ◽  
Author(s):  
Anna Papadopoulou ◽  
Paraskevi C. Fragkou ◽  
Eirini Maratou ◽  
Dimitra Dimopoulou ◽  
Antonis Kominakis ◽  
...  
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Case Control Study ◽  
Case Control ◽  
Converting Enzyme ◽  
Ace Activity ◽  
Control Study

Angiotensin-converting enzyme insertion/deletion gene polymorphism in Egyptian children with CAP: A case-control study

2017 ◽  
Vol 52 (12) ◽  
pp. 1592-1598 ◽  
Author(s):  
Heba Abouzeid ◽  
Usama M. Alkholy ◽  
Mohammed A. Abdou ◽  
Saeed M. Morsy ◽  
Hind M. Abdelrahman ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Angiotensin Converting Enzyme ◽  
Case Control Study ◽  
Case Control ◽  
Converting Enzyme ◽  
Egyptian Children ◽  
Control Study

Angiotensin-converting enzyme and subclinical atherosclerosis in psoriasis: Is there any association? A case-control study

2020 ◽  
Vol 82 (4) ◽  
pp. 980-981.e1 ◽  
Author(s):  
Fahimeh Abdollahimajd ◽  
Nasim Niknezhad ◽  
Hamid Reza Haghighatkhah ◽  
Nastaran Namazi ◽  
Nakisa Niknejad ◽  
...  
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Case Control Study ◽  
Subclinical Atherosclerosis ◽  
Case Control ◽  
Converting Enzyme ◽  
Control Study

scholarly journals Genetic Association of Angiotensin-Converting Enzyme (ACE) Gene I/D Polymorphism with Preterm Birth in Korean Women: Case-Control Study and Meta-Analysis

Medicina ◽  
2019 ◽  
Vol 55 (6) ◽  
pp. 264 ◽  
Author(s):  
Noo Ri Lee ◽  
In Wook Hwang ◽  
Hyung Jun Kim ◽  
Yun Dan Kang ◽  
Jin Wan Park ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Angiotensin Converting Enzyme ◽  
Protective Factor ◽  
Case Control Study ◽  
Genetic Model ◽  
Meta Analysis ◽  
Case Control ◽  
Converting Enzyme ◽  
Ace Gene ◽  
Control Study

Background and Objectives: The ACE gene encodes the angiotensin-converting enzyme (ACE), a component of the renin-angiotensin system. Increased ACE activity may cause abnormal regulation of placental circulation and angiogenesis, resulting in adverse pregnancy outcomes. Previous studies have reported that the insertion/deletion (I/D) polymorphism of the ACE gene is associated with the development of preterm birth (PTB). However, results of the association between ACE gene I/D and PTB are inconsistent in various populations. Therefore, we performed a case-control study and a meta-analysis to evaluate the association between ACE I/D polymorphism and PTB. Materials and Methods: We analyzed a total of 254 subjects (111 patients with PTB and 143 women at ≥38 weeks gestation) for the case-control study. For the meta-analysis, we searched Google Scholar, PubMed, and NCBI databases with the terms “ACE,” “angiotensin-converting enzyme,” “preterm birth,” “preterm delivery,” and their combinations. Results: Our results of the case-control study indicated that ACE I/D polymorphism is significantly associated with PTBs in the overdominant genetic model (odds ratio (OR) 0.57, 95% confidence interval (CI) 0.347–0.949, p = 0.029) and that the ID genotype of ACE I/D polymorphism has a protective effect for PTB (OR 0.57, 95% CI 0.333–0.986, p = 0.043). Similarly, the meta-analysis showed that the OR for the ACE gene ID genotype was 0.66 (95% CI 0.490–0.900, p < 0.01). Conclusion: The ACE gene ID genotype has a significant association with PTB and is a protective factor for PTB. A larger sample set and functional studies are required to further elucidate of our findings.

No association between the angiotensin-converting enzyme gene and major depression: a case???control study and meta-analysis

2006 ◽  
Vol 16 (6) ◽  
pp. 225-226 ◽  
Author(s):  
Sandra L??pez-Le??n ◽  
A. Cecile J.W. Janssens ◽  
Albert Hofman ◽  
Stephan Claes ◽  
Monique M.B. Breteler ◽  
...  
Keyword(s):  
Major Depression ◽  
Angiotensin Converting Enzyme ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
Angiotensin Converting Enzyme Gene ◽  
Converting Enzyme ◽  
Enzyme Gene ◽  
Control Study
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