scholarly journals Safety and efficacy of grazoprevir/elbasvir in the treatment of acute hepatitis C in hemodialysis patients

2021 ◽  
Author(s):  
Qinghua Ji ◽  
Xudong Chu ◽  
Yugui Zhou ◽  
Xuan Liu ◽  
Wei Zhao ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Acute Hepatitis ◽  
Hemodialysis Patients ◽  
Acute Hepatitis C ◽  
Safety And Efficacy

scholarly journals Pegylated Interferon Alfa‐2a Monotherapy for Hemodialysis Patients with Acute Hepatitis C

2010 ◽  
Vol 51 (5) ◽  
pp. 541-549 ◽  
Author(s):  
Chen‐Hua Liu ◽  
Cheng‐Chao Liang ◽  
Chun‐Jen Liu ◽  
Jou‐Wei Lin ◽  
Shih‐I Chen ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Acute Hepatitis ◽  
Pegylated Interferon ◽  
Hemodialysis Patients ◽  
Interferon Alfa ◽  
Acute Hepatitis C ◽  
Pegylated Interferon Alfa

Acute hepatitis C among japanese hemodialysis patients: A prospective 9-year study

2001 ◽  
Vol 96 (5) ◽  
pp. 1592-1600 ◽  
Author(s):  
Norihiro Furusyo ◽  
Jun Hayashi ◽  
Kyoji Kakuda ◽  
Iwao Ariyama ◽  
Yoko Kanamoto-Tanaka ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Acute Hepatitis ◽  
Hemodialysis Patients ◽  
Acute Hepatitis C

scholarly journals Acute hepatitis C virus infection assessment among chronic hemodialysis patients in the Southwest Parana State, Brazil

2007 ◽  
Vol 7 (1) ◽  
Author(s):  
Maricea Engel ◽  
Fernanda M Malta ◽  
Michele MS Gomes ◽  
Isabel MVGC Mello ◽  
João RR Pinho ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Infection ◽  
Acute Hepatitis ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Acute Hepatitis C ◽  
Hepatitis C Virus Infection

Recognizing Acute Hepatitis C in Hemodialysis Patients

2008 ◽  
Vol 53 (12) ◽  
pp. 3267-3268 ◽  
Author(s):  
Resat Ozaras ◽  
Mesut Yilmaz ◽  
Birgul Mete ◽  
Aslihan Demirel ◽  
Veysel Tahan
Keyword(s):  
Hepatitis C ◽  
Acute Hepatitis ◽  
Hemodialysis Patients ◽  
Acute Hepatitis C

Treatment of acute hepatitis C infection with interferon-alfa 2b monotherapy prevents development of chronic HCV infection

2001 ◽  
Vol 120 (5) ◽  
pp. A567-A567 ◽  
Author(s):  
E JAECKEL ◽  
M CORNBERG ◽  
T SANTANTONIO ◽  
J MAYER ◽  
H WEDEMEYER ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Acute Hepatitis ◽  
Interferon Alfa ◽  
Hcv Infection ◽  
Acute Hepatitis C ◽  
Hepatitis C Infection ◽  
Chronic Hcv Infection ◽  
Chronic Hcv

Acute Hepatitis C in Haemophiliacs Due to “Virus-Inactivated” Clotting Factor Concentrates

1992 ◽  
Vol 68 (06) ◽  
pp. 781-781 ◽  
Author(s):  
A Gerritzen ◽  
B Scholt ◽  
R Kaiser ◽  
K E Schneweis ◽  
H-H Brackmann ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Acute Hepatitis ◽  
Clotting Factor ◽  
Acute Hepatitis C ◽  
Clotting Factor Concentrates

Long-lasting Imprint in the Soluble Inflammatory Milieu despite Early Treatment of Acute Symptomatic Hepatitis C

2021 ◽  
Author(s):  
Tanvi Khera ◽  
Yanqin Du ◽  
Daniel Todt ◽  
Katja Deterding ◽  
Benedikt Strunz ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Acute Hepatitis ◽  
Acute Hepatitis C ◽  
Hepatitis C Infection ◽  
Partial Restoration ◽  
Acute Hcv ◽  
Direct Acting ◽  
Inflammatory Milieu

Abstract Background Treatment with direct acting antivirals (DAAs) in patients with chronic hepatitis C infection leads to partial restoration of soluble inflammatory mediators (SIMs). In contrast, we hypothesized that early DAA treatment of acute hepatitis C with DAAs may normalize most SIMs. Methods In this study, we made use of a unique cohort of acute symptomatic hepatitis C who cleared HCV with a 6-week course of ledipasvir/sofosbuvir. Plasma samples were used for proximity extension assay (PEA) measuring 92 proteins. Results Profound SIM alterations were observed in acute HCV patients, with marked upregulation of IL-6 and CXCL10 while certain mediators were down-regulated (e.g. MCP-4, IL-7). During treatment and follow-up, the majority of SIMs decreased but not all normalized (e.g. CDCP1, IL-18). Of note, SIMs that were down-regulated before DAA treatment remained suppressed while others that were initially unchanged, declined to lower values during treatment and follow-up (e.g.CD244). Conclusions Acute hepatitis C was associated with marked changes in the soluble inflammatory milieu as compared to both chronic hepatitis patients and healthy controls. Whereas early DAA treatment partly normalized this altered signature, long-lasting imprints of HCV remained. Thus, acute HCV-induced changes in the immune system may persist even after a short duration of viremia.

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