scholarly journals Association of GSTM1 and GSTT1 gene polymorphisms with COVID‐19 susceptibility and its outcome

Author(s):  
Mohammad Abbas ◽  
Sushma Verma ◽  
Shrikant Verma ◽  
Sahabjada Siddiqui ◽  
Faizan Haider Khan ◽  
...  
2020 ◽  
Vol 21 (8) ◽  
pp. 2251-2257
Author(s):  
Phakarat Tangkhuenkhan ◽  
Kitiphong Harncharoen ◽  
Somchai Thanasitthichai ◽  
Danai Tiwawech ◽  
Wichai Purisa ◽  
...  

2014 ◽  
Vol 33 (3) ◽  
pp. 259-264 ◽  
Author(s):  
Fang-Chun Sun ◽  
Ya-Chung Jeng ◽  
Meng-Shiou Lee ◽  
Chen-Fan Wen ◽  
Tsung-Ming Chen ◽  
...  

Abstract Background: This study was conducted to evaluate the influence of glutathione-S-transferase (GST) M1 and T1 polymorphisms in 184 patients with different stages of liver fibrosis and hepatitis C virus infection and 173 healthy control subjects. Methods: DNA samples were extracted from whole blood, and the polymorphisms of GSTM1 and GSTT1 were determined with PCR using fluorescence-labeled Taq Man probes. Associations between specific genotypes and progression of liver fibrosis were examined by use of the logistic regression analysis to calculate the odds ratio (OR) and 95% confidence intervals (CI). Results: Results show that no differences were found between the frequencies of GSTM1 (49.8% versus 50.2%) and GSTT1 (52.2% versus 47.8%) null genotypes in HCV-infected pa tients and healthy controls, respectively. In addition, there was also no significant relation between the frequency of GSTM1 or GSTT1 gene polymorphisms and fibrosis stage as classified by the METAVIR group. Conclusions: The combined GSTM1 and GSTT1 null genotypes showed an association between GSTM1 [-]/GSTT1 [- ] and progression of liver fibrosis.


2018 ◽  
Vol 22 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Liping Ma ◽  
Biyang Lan ◽  
Lingxiao Guo ◽  
Shaoyun Nong ◽  
Cuibo Huang ◽  
...  

Author(s):  
Vidyullatha Peddireddy ◽  
Siva Prasad Badabagni ◽  
Sandhya Devi Gundimeda ◽  
Vasudha Mamidipudi ◽  
Pardhanandana Reddy Penagaluru ◽  
...  

2008 ◽  
Vol 41 (2) ◽  
pp. 259-266 ◽  
Author(s):  
Ertan Altayli ◽  
Sezgin Gunes ◽  
Ali Faik Yilmaz ◽  
Serdar Goktas ◽  
Yuksel Bek

2005 ◽  
Vol 50 (12) ◽  
pp. 618-627 ◽  
Author(s):  
Leelakumari Sreeja ◽  
Vani Syamala ◽  
Sreedharan Hariharan ◽  
Jayaprakash Madhavan ◽  
Sivanandan Choondal Devan ◽  
...  

2012 ◽  
Vol 13 (3) ◽  
pp. 815-819 ◽  
Author(s):  
Zhen-Yong Zhang ◽  
Xue-Ying Jin ◽  
Rong Wu ◽  
Li-Na Wu ◽  
Rui Xing ◽  
...  

Tumor Biology ◽  
2013 ◽  
Vol 34 (3) ◽  
pp. 1431-1440 ◽  
Author(s):  
Jihong Wang ◽  
Yuemin Xu ◽  
Qiang Fu ◽  
Jianjun Yu ◽  
Zhong Chen ◽  
...  

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