Distribution of the Epstein-Barr virus in the normal stomach and gastric lesions in Thai population

2018 ◽  
Vol 91 (3) ◽  
pp. 444-449 ◽  
Author(s):  
Supitcha Wanvimonsuk ◽  
Pichaya Thitiwanichpiwong ◽  
Somboon Keelawat ◽  
Apiwat Mutirangura ◽  
Nakarin Kitkumthorn
Keyword(s):  
Epstein Barr Virus ◽  
Gastric Lesions ◽  
Thai Population ◽  
Barr Virus ◽  
Epstein Barr ◽  
Normal Stomach

scholarly journals Association of Epstein–Barr virus antibody levels with precancerous gastric lesions in a high-risk cohort

2008 ◽  
Vol 99 (2) ◽  
pp. 350-354 ◽  
Author(s):  
Aaron J. Schetter ◽  
Wei-cheng You ◽  
Evelyne T. Lennette ◽  
Mitchell T. Gail ◽  
Charles S. Rabkin
Keyword(s):  
High Risk ◽  
Epstein Barr Virus ◽  
Gastric Lesions ◽  
Virus Antibody ◽  
Barr Virus ◽  
Precancerous Gastric Lesions ◽  
Epstein Barr ◽  
Antibody Levels ◽  
High Risk Cohort

scholarly journals Epstein–Barr virus strains defined by the latent membrane protein 1 sequence characterize Thai ethnic groups

2010 ◽  
Vol 91 (8) ◽  
pp. 2054-2061 ◽  
Author(s):  
Vannarat Saechan ◽  
Wannapa Settheetham-Ishida ◽  
Ryosuke Kimura ◽  
Danai Tiwawech ◽  
Winyou Mitarnun ◽  
...  
Keyword(s):  
Membrane Protein ◽  
Ethnic Groups ◽  
Epstein Barr Virus ◽  
Latent Membrane Protein ◽  
Latent Membrane Protein 1 ◽  
Thai Population ◽  
Barr Virus ◽  
Virus Diversity ◽  
Epstein Barr ◽  
Linguistic Groups

Epstein–Barr virus (EBV) is ubiquitous in the human population and seroepidemiological studies have revealed that more than 90 % of adults are infected with the virus in Thailand. It has been suggested that latent membrane protein 1 (LMP1) variants may differ in their tumorigenicity and geographical localization. The distribution of LMP1 variants of EBV in the Thai population was studied. A total of 259 LMP1 sequences from ten Thai ethnic groups (Lahu, Lisu, Shan, Red Karen, White Karen, Hmong, Akha, Mlabri, Moken and Urak Lawoi) were studied using direct PCR sequencing. Nucleotide sequences corresponding to the C terminus of the LMP1, including previously published sequences from central and southern Thais, were used in the phylogenetic analysis. Five strains – the B95-8 prototype, China 1, China 2, Mediterranean (Med) and SEA 2 – were identified in ethnic groups in Thailand. The major strain and the distribution pattern differed by group and location. When the ethnic groups were classified by linguistic group, the prevalence of the SEA 2 strain was significantly different between Austro-Thais and other linguistic groups (P=0.0001), whereas, among Tibeto-Burman linguistic groups, the prevalence of the Med strain was different between matrilocal and patrilocal groups (P=0.0245). The distribution of LMP1 strains in ethnic minorities in Thailand is associated with ethnogeographical factors and the social/marriage system. This study thus provides evidence for the importance of interactions between populations in virus diversity.

A Quantitative Ultrastructural Study of Peripheral Blood Lymphocytes Containing Parallel Tubular Arrays in Epstein-Barr Virus and Cytomegalo-Virus Mononucleosis

1981 ◽  
Vol 39 ◽  
pp. 454-455
Author(s):  
C. M. Payne ◽  
P. M. Tennican
Keyword(s):  
Peripheral Blood ◽  
Lymphocyte Count ◽  
Epstein Barr Virus ◽  
Absolute Lymphocyte Count ◽  
Peripheral Blood Lymphocytes ◽  
Clinical State ◽  
Barr Virus ◽  
The Absolute ◽  
Epstein Barr ◽  
Tubular Arrays

In the normal peripheral circulation there exists a sub-population of lymphocytes which is ultrastructurally distinct. This lymphocyte is identified under the electron microscope by the presence of cytoplasmic microtubular-like inclusions called parallel tubular arrays (PTA) (Figure 1), and contains Fc-receptors for cytophilic antibody. In this study, lymphocytes containing PTA (PTA-lymphocytes) were quantitated from serial peripheral blood specimens obtained from two patients with Epstein -Barr Virus mononucleosis and two patients with cytomegalovirus mononucleosis. This data was then correlated with the clinical state of the patient.It was determined that both the percentage and absolute number of PTA- lymphocytes was highest during the acute phase of the illness. In follow-up specimens, three of the four patients' absolute lymphocyte count fell to within normal limits before the absolute PTA-lymphocyte count.In one patient who was followed for almost a year, the absolute PTA- lymphocyte count was consistently elevated (Figure 2). The estimation of absolute PTA-lymphocyte counts was determined to be valid after a morphometric analysis of the cellular areas occupied by PTA during the acute and convalescent phases of the disease revealed no statistical differences.

Studies of Epstein-Barr Virus Antigens Using Immunoperoxidase and Immunofluorescence Techniques

1975 ◽  
Vol 33 ◽  
pp. 342-343
Author(s):  
R. Stephens ◽  
K. Traul ◽  
D. Woolf ◽  
P. Gaudreau
Keyword(s):  
Electron Microscopy ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
If Technique ◽  
Infected Cells ◽  
Virus Antigens ◽  
Epstein Barr ◽  
Virus Capsid Antigen ◽  
Antigen Reactivity

A number of antigens have been found associated with persistent EBV infections of lymphoblastoid cells. Identification and localization of these antigens were principally by immunofluorescence (IF) techniques using sera from patients with nasopharyngeal carcinoma (NPC), Burkitt lymphoma (BL), and infectious mononucleosis (IM). Our study was mainly with three of the EBV related antigens, a) virus capsid antigen (VCA), b) membrane antigen (MA), and c) early antigens (EA) using immunoperoxidase (IP) techniques with electron microscopy (EM) to elucidate the sites of reactivity with EBV and EBV infected cells.Prior to labeling with horseradish peroxidase (HRP), sera from NPC, IM, and BL cases were characterized for various reactivities by the indirect IF technique. Modifications of the direct IP procedure described by Shabo and the indirect IP procedure of Leduc were made to enhance penetration of the cells and preservation of antigen reactivity.

Quantitative analysis of circulating cell-free Epstein-Barr virus (EBV) DNA levels in patients with EBV-associated lymphoid malignancies

2000 ◽  
Vol 111 (1) ◽  
pp. 239-246 ◽  
Author(s):  
Kenny I. K. Lei ◽  
Lisa Y.S. Chan ◽  
Wing Y. Chan ◽  
Philip J. Johnson ◽  
Y. M. Dennis Lo
Keyword(s):  
Quantitative Analysis ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Lymphoid Malignancies ◽  
Ebv Dna ◽  
Epstein Barr

Chronic bullous disease of childhood following Epstein-Barr virus seroconversion: a case report

1996 ◽  
Vol 21 (2) ◽  
pp. 123-126
Author(s):  
U. BALDARI ◽  
A. ASCARI RACCAGNI ◽  
B. CELLI ◽  
M. GIOVANNA RIGHINI
Keyword(s):  
Case Report ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Bullous Disease ◽  
Epstein Barr
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