Increased prevalence of human herpesvirus type 8 (HHV-8) genome among blood donors from North-Western Argentina

2016 ◽  
Vol 89 (3) ◽  
pp. 518-527 ◽  
Author(s):  
María Laura Hulaniuk ◽  
Oscar Torres ◽  
Sonia Bartoli ◽  
Lisandro Fortuny ◽  
Leandro Burgos Pratx ◽  
...  
Keyword(s):  
Blood Donors ◽  
Human Herpesvirus ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type ◽  
North Western

Human herpesvirus type 8 among Brazilian blood donors

Transfusion ◽  
2003 ◽  
Vol 43 (12) ◽  
pp. 1764-1765 ◽  
Author(s):  
Suzete Ferreira ◽  
Sabri Sanabani ◽  
Alexandra D. Reis ◽  
Dalton F. Chamone ◽  
Ester C. Sabino
Keyword(s):  
Blood Donors ◽  
Human Herpesvirus ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type

scholarly journals Production of IgM antibody to HHV6 in reactivation and primary infection

1990 ◽  
Vol 104 (2) ◽  
pp. 289-296 ◽  
Author(s):  
J. D. Fox ◽  
P. Ward ◽  
M. Briggs ◽  
W. Irving ◽  
T. G. Stammers ◽  
...  
Keyword(s):  
Blood Donors ◽  
Human Herpesvirus ◽  
The Other ◽  
Cmv Infection ◽  
Igg Antibody ◽  
Herpesvirus Type ◽  
Barr Virus ◽  
Human Herpesvirus Type ◽  
Epstein Barr ◽  
Simplex Virus

SUMMARYThe cross-reaction of HHV6 antibody with that to the other herpesviruses was studied in 96 blood donors whose sera were tested for IgG antibody to human herpesvirus type 6 (HHV6), cytomegalovirus (CMV), Epstein–Barr virus (EBV), varicella zostervirus (VZV) and herpes simplex virus (HSV). No correlation was found between IgG antibody to HHV6 and that to any of the other herpesviruses in these individuals. Antibodies to HHV6 and CMV were measured in patients undergoing documented serological responses to HHV6. Eleven cases of primary HHV6 infection associated with roseola infantum in babies, 1 of whom suffered from gastroenteritis as well as pyrexia and rash, are reported. Three cases of HHV6 reactivation, 1 in a 3-year-old child and 2 in adults, 1 of whom simultaneously underwent a primary CMV infection are also reported. Our results suggest that indirect immunofluorescence is a specific way of measuring HHV6 antibody, that HHV6 IgG and IgM can be detected in the absence of antibody to CMV and that HHV6 IgM is present both in primary HHV6 infections and in reactivations.

Quantification of viral genome in cord blood donors by real time PCR to investigate human herpesvirus type 8 active infection

2015 ◽  
Vol 53 (3) ◽  
pp. 378-380 ◽  
Author(s):  
Neda Golchin ◽  
Maryam Kheirandish ◽  
Zohreh Sharifi ◽  
Shahram Samiee ◽  
Parviz Kokhaei ◽  
...  
Keyword(s):  
Cord Blood ◽  
Real Time ◽  
Real Time Pcr ◽  
Viral Genome ◽  
Blood Donors ◽  
Human Herpesvirus ◽  
Active Infection ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type

Human herpesvirus type 7 in blood donors: Detection by the polymerase chain reaction

1995 ◽  
Vol 47 (1) ◽  
pp. 65-69 ◽  
Author(s):  
F. Wilborn ◽  
C. A. Schmidt ◽  
F. Lorenz ◽  
R. Peng ◽  
H. Gelderblom ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Blood Donors ◽  
Human Herpesvirus ◽  
Chain Reaction ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type ◽  
Polymerase Chain

scholarly journals Immunohistochemical detection of the latent nuclear antigen-1 of the human herpesvirus type 8 to differentiate cutaneous epidemic Kaposi sarcoma and its histological simulators

2013 ◽  
Vol 88 (2) ◽  
pp. 243-246 ◽  
Author(s):  
Patricia Fonseca Pereira ◽  
Tullia Cuzzi ◽  
Maria Clara Gutierrez Galhardo
Keyword(s):  
Kaposi's Sarcoma ◽  
Human Herpesvirus ◽  
Kaposi Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Nuclear Antigen ◽  
Immunohistochemical Detection ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type ◽  
Skin Biopsies ◽  
Latent Nuclear Antigen

Kaposi's sarcoma is the most common neoplasia diagnosed in AIDS patients and the expression of the human herpesvirus-8 (HHV-8) latent nuclear antigen-1 has been useful for its histological diagnosis. The aim of this study is to confirm that immunohistochemistry is a valuable tool for differentiating KS from its simulators in skin biopsies of HIV patients. Immunohistochemical and histological analyses were performed in 49 Kaposi's sarcoma skin biopsies and 60 of its histological simulators. Positivity was present in the 49 Kaposi's sarcoma skin biopsies and no staining was observed in the 60 simulators analyzed, resulting in sensibility and specificity of 100%. HHV-8 immunohistochemical detection is an effective tool for diagnosing Kaposi's sarcoma, especially in early lesions in which neoplastic features are not evident. It also contributes to its histological differential diagnosis.

scholarly journals Clinical Aspects of Bacterial Corneal Ulcer Prolonged Course, the Role of Herpes Viruses in Its Pathogenesis, Treatment

2019 ◽  
Vol 16 (1S) ◽  
pp. 40-44
Author(s):  
V. V. Neroev ◽  
L. A. Katargina ◽  
L. A. Kovaleva ◽  
G. I. Krichevskaya ◽  
N. V. Balatskaya
Keyword(s):  
Corneal Ulcer ◽  
Human Herpesvirus ◽  
Clinical Aspects ◽  
Herpesvirus Type ◽  
Corneal Ulcers ◽  
Barr Virus ◽  
Human Herpesvirus Type ◽  
Epstein Barr ◽  
Simplex Virus

Purpose: to study the role of human herpesviruses (HHV) in the pathogenesis of prolonged bacterial corneal ulcers. Patients and methods. 117 patients with bacterial corneal ulcer were examined. Two groups were identified: a favorable course-with duration of bacterial corneal ulcer epithelialization for 17 days (62 people) and a prolonged course with a persistent ulcer more than 17 days (55 people). Blood samples (n = 117) and scrapes from corneal ulcer (n = 117) were investigated in polymerase chain reaction (PCR) for the presence of deoxyribonucleic acid (DNA) of Herpes simplex virus (HSV1, 2), Epstein-Barr virus (EBV), Human herpesvirus type 6, 7 (HHV-6, HSV-7). Results. The HSV1, 2 and EBV genomes were detected in the cornea significantly more often in BCU of prolonged course compared with a favorable course (HSV1, 2 p = 0.012; EBV p = 0.012), and HHV-6 was detected not only in the cornea (p = 0.000), but also and in blood (p = 0.007). In patients with HHV DNA in corneal scarps and/or blood, after resorption of purulent infiltrate, corneal epithelialization was absent, and the use of antiherpetic drugs allowed to reduce the completion time of BCU epithelialization. Conclusion. The role of HHV-6, EBV, HSV 1, 2 in the pathogenesis of bacterial corneal ulcer of protracted course was revealed. The expediency of examination of patients with bacterial corneal ulcer on HHV is shown, a method of treatment is proposed, including antiherpetic therapy, which makes it possible to prevent the development of a protracted course.

Kutapressin Inhibits In Vitro Infection of Human Herpesvirus Type 6

1994 ◽  
Vol 18 (Supplement_1) ◽  
pp. S113-S113
Author(s):  
D. V. Ablashi ◽  
Z. Berneman ◽  
C. Lawyer ◽  
A. Komaroff
Keyword(s):  
Human Herpesvirus ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type
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