Correlation between anti-JC-virus and anti-cytomegalovirus, -Epstein-Barr virus and -measles/-rubella/-varicella-zoster-virus antibodies

2016 ◽  
Vol 89 (1) ◽  
pp. 3-9 ◽  
Author(s):  
Michael Auer ◽  
Wegene Borena ◽  
Dorothee Holm-von Laer ◽  
Florian Deisenhammer
Keyword(s):  
Varicella Zoster Virus ◽  
Epstein Barr Virus ◽  
Jc Virus ◽  
Varicella Zoster ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Polymerase chain reaction for the laboratory diagnosis of aseptic meningitis and encephalitis

2000 ◽  
Vol 58 (3B) ◽  
pp. 836-842 ◽  
Author(s):  
MARISA CHESKY ◽  
ROSANA SCALCO ◽  
LUCIANE FAILACE ◽  
STEVEN READ ◽  
LUIZ FERNANDO JOBIM
Keyword(s):  
Epstein Barr Virus ◽  
Jc Virus ◽  
Human Herpes ◽  
Varicella Zoster ◽  
Barr Virus ◽  
Human Herpes Virus ◽  
Pcr Assays ◽  
Epstein Barr ◽  
Simplex Virus ◽  
Human Herpes Virus Type

A protocol for testing cerebrospinal fluid specimens using a range of PCR assays for the diagnosis of central nervous system infection was developed and used to test prospectively 383 specimens. PCR assays were used for the detection of adenovirus, Borrelia burgdorferi, enteroviruses, Epstein Barr virus, cytomegalovirus, herpes simplex virus, human herpes virus type 6, JC virus, Leptospira interrogans, Listeria monocytogenes, lymphocytic choriomeningitis virus, measles virus, mumps virus, Mycobacterium sp., Mycoplasma pneumoniae, Toxoplasma gondii and varicella zoster virus. Of the 383 specimens tested in this study, 46 (12.0%) were found to be positive. The microorganisms detected were CMV, enterovirus, Epstein Barr virus, herpes simplex virus, human herpes virus type 6, JC virus, L. monocytogenes, Mycobacterium genus, Toxoplasma gondii and varicella zoster virus. The introduction of the PCR protocol described has improved the diagnosis of a range of central nervous system infections in our laboratory. We believe however that further evaluation of these assays in immunocompromised patients is necessary to better determine the predictive value of positive PCR results in these patient groups.

Monitoring of Epstein-Barr virus (EBV)/cytomegalovirus (CMV)/varicella-zoster virus (VZV) load in patients receiving tocilizumab for rheumatoid arthritis

2016 ◽  
Vol 83 (4) ◽  
pp. 412-415 ◽  
Author(s):  
Cindy Mourgues ◽  
Cecile Henquell ◽  
Zuzana Tatar ◽  
Bruno Pereira ◽  
Cinthya Nourisson ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Varicella Zoster Virus ◽  
Epstein Barr Virus ◽  
Varicella Zoster ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals A Randomized Double-Blind Placebo Controlled Trial of Oral Acyclovir in Renal Allograft Recipients

1993 ◽  
Vol 4 (2) ◽  
pp. 84-88 ◽  
Author(s):  
Walter F Schlech ◽  
Nancy Meagher ◽  
Allan D Cohen ◽  
Philip Belitsky ◽  
AS MacDonald ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Varicella Zoster Virus ◽  
Epstein Barr Virus ◽  
Oral Acyclovir ◽  
Cmv Infection ◽  
Varicella Zoster ◽  
Barr Virus ◽  
Epstein Barr ◽  
Simplex Virus

Fifty renal transplant patients were randomized to receive either 800 mg acyclovir by mouth four times daily or identical placebo tablets for prophylaxis of herpes simplex infection. Patients were followed weekly to assess reactivation of herpes simplex, varicella zoster virus, Epstein-Barr virus or cytomegalovirus (CMV) infections. The patients received standard immunosuppressive regimens including cyclosporine A. Acyclovir suppressed secretion of herpes simplex virus in treated patients (P=0.001). Three episodes of mucocutaneous herpes simplex virus occurred in placebo recipients and one in a noncompliant acyclovir recipient. A clinically important difference in graft survival was demonstrated, but because of sample size failed to reach statistical significance (P=0.11). No reactivation of varicella zoster virus, Epstein-Barr virus or CMV infection was detected in either group. Toxicity was limited to central nervous irritability. The authors conclude that high dose oral acyclovir provides effective prophylaxis for prevention of herpes simplex virus infections in renal transplantation and may be associated with increased graft survival, perhaps from suppression of CMV infection.

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