scholarly journals Role of inflammasome genetics in susceptibility to HPV infection and cervical cancer development

2016 ◽  
Vol 88 (9) ◽  
pp. 1646-1651 ◽  
Author(s):  
A. Pontillo ◽  
P. Bricher ◽  
V.N.C. Leal ◽  
S. Lima ◽  
P.R.E. Souza ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Hpv Infection ◽  
Cancer Development ◽  
Cervical Cancer Development

Role of ganglioside biosynthesis genetic polymorphism in cervical cancer development

2019 ◽  
Vol 40 (8) ◽  
pp. 1127-1132
Author(s):  
Damir Danolic ◽  
Marija Heffer ◽  
Jasenka Wagner ◽  
Ivana Skrlec ◽  
Ilija Alvir ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Genetic Polymorphism ◽  
Cancer Development ◽  
Ganglioside Biosynthesis ◽  
Cervical Cancer Development

scholarly journals Role of ganglioside GM1 expression in T lymphocytes membranes in cervical cancer development

2019 ◽  
Author(s):  
Danolic Damir ◽  
Marija Heffer ◽  
Jasenka Wagner ◽  
Ivana Skrlec ◽  
Ilija Alvir ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
T Lymphocytes ◽  
Cancer Development ◽  
Ganglioside Gm1 ◽  
Cervical Cancer Development

scholarly journals The Preventive Effect of Dietary Antioxidants on Cervical Cancer Development

Medicina ◽  
2020 ◽  
Vol 56 (11) ◽  
pp. 604
Author(s):  
Ayumi Ono ◽  
Masafumi Koshiyama ◽  
Miwa Nakagawa ◽  
Yumiko Watanabe ◽  
Eri Ikuta ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Nutrient Intake ◽  
Continuous Process ◽  
Relevant Literature ◽  
Hpv Infection ◽  
Cancer Development ◽  
Dietary Antioxidants ◽  
Cervical Cancer Development

Cervical cancer results from a continuous process, starting from a normal cervical epithelium after human papillomavirus (HPV) infection and progressing to cervical intraepithelial neoplasia (CIN), before finally developing into invasive squamous carcinoma (ISC). In recent decades, dietary antioxidants, such as vitamins, have received much attention in relation to cancer prevention. We reviewed the relevant literature to investigate the dietary and nutrient intake on cervical cancer. The intake of vitamins A and D and carotenoids may inhibit early cervical cancer development. The intake of folate may prevent or inhibit HPV infection rom progressing to various grades of CIN. The intake of vitamins C and E may widely inhibit the process of cervical cancer development. Polyphenols are often used in cases of cervical cancer in combination chemotherapy and radiation therapy. Regarding nutrients, different antioxidants may have differing abilities to intervene in the natural history of cervical diseases associated with HPV infection. Regarding foods, the intake of both vegetables and fruits containing multiple vitamins may widely suppress cervical cancer development. Most previous papers have described epidemiological studies. Thus, further research using in vitro and in vivo approaches will be needed to clarify the effects of the dietary and nutrient intake in detail.

scholarly journals A Systematic Review of MicroRNAs Involved in Cervical Cancer Progression

Cells ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 668
Author(s):  
Rhafaela Lima Causin ◽  
Ana Julia Aguiar de Freitas ◽  
Cassio Murilo Trovo Hidalgo Filho ◽  
Ricardo dos Reis ◽  
Rui Manuel Reis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cervical Cancer ◽  
Cancer Progression ◽  
Cancer Development ◽  
Tissue Samples ◽  
Regulatory Pathways ◽  
Gynecology And Obstetrics ◽  
Cervical Cancer Development ◽  
Proliferative Signaling

To obtain a better understanding on the role of microRNAs in the progression of cervical cancer, a systematic review was performed to analyze cervical cancer microRNA studies. We provide an overview of the studies investigating microRNA expression in relation to cervical cancer (CC) progression, highlighting their common outcomes and target gene interactions according to the regulatory pathways. To achieve this, we systematically searched through PubMed MEDLINE, EMBASE, and Google Scholar for all articles between April 2010 and April 2020, in accordance with the PICO acronym (participants, interventions, comparisons, outcomes). From 27 published reports, totaling 1721 cases and 1361 noncancerous control tissue samples, 26 differentially expressed microRNAs (DEmiRNAs) were identified in different International Federation of Gynecology and Obstetrics (FIGO) stages of cervical cancer development. It was identified that some of the dysregulated microRNAs were associated with specific stages of cervical cancer development. The results indicated that DEmiRNAs in different stages of cervical cancer were functionally involved in several key hallmarks of cancer, such as evading growth suppressors, enabling replicative immortality, activation of invasion and metastasis, resisting cell death, and sustained proliferative signaling. These dysregulated microRNAs could play an important role in cervical cancer’s development. Some of the stage-specific microRNAs can also be used as biomarkers for cancer classification and monitoring the progression of cervical cancer.

scholarly journals Oncogenic role of Tc17 cells in cervical cancer development

2020 ◽  
Vol 8 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Zun-Sheng Zhang ◽  
Ying Gu ◽  
Bing-Gang Liu ◽  
Hong Tang ◽  
Yu Hua ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Development ◽  
Tc17 Cells ◽  
Cervical Cancer Development
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