MicroRNA profile analysis of host cells before and after wild human rotavirus infection

2016 ◽  
Vol 88 (9) ◽  
pp. 1497-1510 ◽  
Author(s):  
Yan Zhou ◽  
Jinyuan Wu ◽  
Panpan Geng ◽  
Xiang Kui ◽  
Yuping Xie ◽  
...  
Keyword(s):  
Profile Analysis ◽  
Host Cells ◽  
Rotavirus Infection ◽  
Human Rotavirus ◽  
Before And After ◽  
Microrna Profile

MicroRNA profile analysis of a feline kidney cell line before and after infection with mink enteritis virus

Gene ◽  
2014 ◽  
Vol 539 (2) ◽  
pp. 224-229 ◽  
Author(s):  
Jia-zeng Sun ◽  
Jigui Wang ◽  
Shuang Wang ◽  
Daoli Yuan ◽  
Basse Mame Birame ◽  
...  
Keyword(s):  
Cell Line ◽  
Kidney Cell ◽  
Profile Analysis ◽  
Kidney Cell Line ◽  
Mink Enteritis Virus ◽  
Before And After ◽  
Microrna Profile ◽  
Enteritis Virus

How Collective-Action Failure Shapes Group Heterogeneity and Engagement in Conventional and Radical Action Over Time

2021 ◽  
pp. 095679762097056
Author(s):  
Morgana Lizzio-Wilson ◽  
Emma F. Thomas ◽  
Winnifred R. Louis ◽  
Brittany Wilcockson ◽  
Catherine E. Amiot ◽  
...  
Keyword(s):  
Social Movements ◽  
Collective Action ◽  
Latent Profile Analysis ◽  
Profile Analysis ◽  
Social Identification ◽  
Future Research ◽  
Group Efficacy ◽  
Before And After ◽  
Using Data ◽  
Over Time

Extensive research has identified factors influencing collective-action participation. However, less is known about how collective-action outcomes (i.e., success and failure) shape engagement in social movements over time. Using data collected before and after the 2017 marriage-equality debate in Australia, we conducted a latent profile analysis that indicated that success unified supporters of change ( n = 420), whereas failure created subgroups among opponents ( n = 419), reflecting four divergent responses: disengagement (resigned acceptors), moderate disengagement and continued investment (moderates), and renewed commitment to the cause using similar strategies (stay-the-course opponents) or new strategies (innovators). Resigned acceptors were least inclined to act following failure, whereas innovators were generally more likely to engage in conventional action and justify using radical action relative to the other profiles. These divergent reactions were predicted by differing baseline levels of social identification, group efficacy, and anger. Collective-action outcomes dynamically shape participation in social movements; this is an important direction for future research.

scholarly journals In Vitroandin VivoEvaluation of the Efficacy of Bovine Colostrum against Human Rotavirus Infection

2010 ◽  
Vol 74 (3) ◽  
pp. 680-682 ◽  
Author(s):  
Mizuho INAGAKI ◽  
Mayumi YAMAMOTO ◽  
XIJIER ◽  
CAIRANGZHUOMA ◽  
Kenji UCHIDA ◽  
...  
Keyword(s):  
Bovine Colostrum ◽  
Rotavirus Infection ◽  
Human Rotavirus

scholarly journals Effectiveness of live attenuated monovalent human rotavirus vaccination in rural Ecuador, 2008-2013

2018 ◽  
Author(s):  
Alicia N. M. Kraay ◽  
Edward L. Ionides ◽  
Gwenyth O. Lee ◽  
William F. Cevallos Trujillo ◽  
Joseph N.S. Eisenberg
Keyword(s):  
Indirect Effects ◽  
Cox Regression ◽  
Age Groups ◽  
Community Setting ◽  
Population Level ◽  
Population Based ◽  
Case Control ◽  
Rotavirus Infection ◽  
Human Rotavirus ◽  
Overall Effectiveness

AbstractBackgroundWhile live attenuated monovalent human rotavirus vaccine (Rotarix) efficacy has been characterized through randomized studies, its effectiveness, especially in non-clinical settings, is unclear. In this study, we estimate direct, indirect, and overall effectiveness of Rotarix vaccination.MethodsWe analyze 29 months of all-cause diarrhea surveillance from a child cohort (n=376) and ten years of serial population-based case-control lab-confirmed rotavirus data (n=2489) from rural Ecuador during which Rotarix vaccination was introduced. We estimate: 1) the direct effect of vaccination from a cohort of children born from 2008-2013 using Cox regression to compare time to first all-cause diarrhea case by vaccine status; and 2) the overall effect on all-cause diarrheal and symptomatic and asymptomatic rotavirus infection for all age groups, including indirect effects on adults, from the case-control data using weighted logistic regression.ResultsRotarix vaccination provided direct protection against all-cause diarrhea among children 0.5 - 2 years (All-cause diarrhea reduction for receipt of 2 doses of Rotarix=57.1%, 95% CI: 16.6, 77.9%). Overall effectiveness against rotavirus infection was strong (Exposure to 100% coverage of Rotarix vaccination was associated with an 85.5% reduction, 95% CI: 61.1-94.6%) compared to 0% coverage. Indirect effects were observed among older, vaccine-ineligible children and adults (84.5% reduction, 95% CI: 48.2-95.4%). Vaccine effectiveness was high against both symptomatic (48.3% reduction,95% CI: 0.03-73.1%) and asymptomatic infection (90.1% reduction, 95% CI: 56.9-97.7%).ConclusionsRotarix vaccination suppresses overall transmission. It is highly effective among children in a rural community setting and provides population-level benefits through indirect protection among adults.

scholarly journals Innate cellular responses to rotavirus infection

2013 ◽  
Vol 94 (6) ◽  
pp. 1151-1160 ◽  
Author(s):  
Gavan Holloway ◽  
Barbara S. Coulson
Keyword(s):  
Protective Immunity ◽  
Molecular Mechanisms ◽  
Cellular Responses ◽  
Innate Immune ◽  
Host Cells ◽  
Type I ◽  
First Line ◽  
Comprehensive Overview ◽  
Rotavirus Infection ◽  
Infants And Young Children

Rotavirus is a leading cause of severe dehydrating diarrhoea in infants and young children. Following rotavirus infection in the intestine an innate immune response is rapidly triggered. This response leads to the induction of type I and type III interferons (IFNs) and other cytokines, resulting in a reduction in viral replication. Here we review the current literature describing the detection of rotavirus infection by pattern recognition receptors within host cells, the subsequent molecular mechanisms leading to IFN and cytokine production, and the processes leading to reduced rotavirus replication and the development of protective immunity. Rotavirus countermeasures against innate responses, and their roles in modulating rotavirus replication in mice, also are discussed. By linking these different aspects of innate immunity, we provide a comprehensive overview of the host’s first line of defence against rotavirus infection. Understanding these processes is expected to be of benefit in improving strategies to combat rotavirus disease.

Influence of Temperature and Relative Humidity on Human Rotavirus Infection in Japan

1983 ◽  
Vol 147 (1) ◽  
pp. 125-128 ◽  
Author(s):  
T. Konno ◽  
H. Suzuki ◽  
N. Katsushima ◽  
A. Imai ◽  
F. Tazawa ◽  
...  
Keyword(s):  
Relative Humidity ◽  
Influence Of Temperature ◽  
Rotavirus Infection ◽  
Human Rotavirus
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