Analysis of HBV genotype, drug resistant mutations, and pre-core/basal core promoter mutations in Korean patients with acute hepatitis B

2015 ◽  
Vol 87 (6) ◽  
pp. 993-998 ◽  
Author(s):  
Jong Ho Lee ◽  
Sun Pyo Hong ◽  
Eun Sun Jang ◽  
Sang Jong Park ◽  
Seong Gyu Hwang ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Acute Hepatitis ◽  
Core Promoter ◽  
Basal Core Promoter ◽  
Drug Resistant ◽  
Hbv Genotype ◽  
Korean Patients ◽  
Acute Hepatitis B ◽  
Promoter Mutations

scholarly journals Prevalence of Hepatitis B Virus Subgenotypes and Basal Core Promoter, Precore Variants in Patients with Acute Hepatitis B in Central Vietnam

Intervirology ◽  
2009 ◽  
Vol 52 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Kazuhiko Hayashi ◽  
Yoshiaki Katano ◽  
Tran Xuan Chuong ◽  
Yasushi Takeda ◽  
Masatoshi Ishigami ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Acute Hepatitis ◽  
Core Promoter ◽  
Basal Core Promoter ◽  
Central Vietnam ◽  
B Virus ◽  
Acute Hepatitis B

Acute hepatitis B infection associated with drug-resistant hepatitis B virus

2010 ◽  
Vol 48 (4) ◽  
pp. 270-274 ◽  
Author(s):  
Zhihui Xu ◽  
Yan Liu ◽  
Teng Xu ◽  
Li Chen ◽  
Lanlan Si ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Acute Hepatitis ◽  
Drug Resistant ◽  
Hepatitis B Infection ◽  
B Virus ◽  
Acute Hepatitis B

Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers

2003 ◽  
Vol 124 (2) ◽  
pp. 327-334 ◽  
Author(s):  
Jia–Horng Kao ◽  
Pei–Jer Chen ◽  
Ming–Yang Lai ◽  
Ding–Shinn Chen
Keyword(s):  
Hepatocellular Carcinoma ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
Basal Core Promoter ◽  
B Virus ◽  
Promoter Mutations

scholarly journals Genotyping Hepatitis B virus from whole- and sub-genomic fragments using position-specific scoring matrices in hbv star

2006 ◽  
Vol 87 (6) ◽  
pp. 1459-1464 ◽  
Author(s):  
Richard Myers ◽  
Caroline Clark ◽  
Arshad Khan ◽  
Paul Kellam ◽  
Richard Tedder
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Core Promoter ◽  
Full Length ◽  
Basal Core Promoter ◽  
Hbv Genotype ◽  
Promoter Sequences ◽  
Hbv Genotypes ◽  
Scoring Matrices ◽  
B Virus

Hepatitis B virus (HBV) genomes have been classified into eight genotypes based on phylogenetic analysis of sequence variation. Identifying and tracking the movement of HBV genotypes is important in terms of both monitoring infection rates and predicting disease and treatment. An HBV genotyping tool has been developed that compares query sequences with position-specific scoring matrices representing the eight HBV genotypes. This tool (hbv star) is rapid, robust and accurate and assigns genotype based on a statistically defined scoring model. hbv star confidently assigned 90 % of 590 full-length HBV genomes to an HBV genotype (Z score >2.0). Thirty-two of the residual 48 sequences were identified as non-human primate viruses and 16 sequences were identified as recombinant or putative recombinants. Receiver-Operated Characteristic (ROC) analysis was used to compare the accuracy of genotype prediction using basal core promoter sequences and surface and core genes with the accuracy achieved by using full-length sequences. A web interface to hbv star is available at http://www.vgb.ucl.ac.uk/starn.shtml.

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