Molecular epidemiology of human astrovirus infections in Saudi Arabia pediatric patients

2010 ◽  
Vol 82 (12) ◽  
pp. 2038-2042 ◽  
Author(s):  
Hamsa T. Tayeb ◽  
Mohammed N. Al-Ahdal ◽  
Micheal J. Cartear ◽  
Ahmade A. Al-Qahtani ◽  
Damian M. Dela Cruz
2020 ◽  
Vol 13 (2) ◽  
pp. 372
Author(s):  
S. Haddad ◽  
M. Aly ◽  
S. Al-Johani ◽  
M. Alghoribi ◽  
H. Balkhy

2021 ◽  
Author(s):  
Hongyu Wei ◽  
Pattara Khamrin ◽  
Kattareeya Kumthip ◽  
Arpaporn Yodmeeklin ◽  
Niwat Maneekarn

Abstract ABSTRCT Human astrovirus (HAstV) is one of the common causes of acute gastroenteritis in children. The investigation of the molecular epidemiology of HAstV is essential for monitoring the emergence and/or re-emergence of new HAstV genotypes, as well as understanding the evolution of HAstV genotypes circulating in children suffering from acute gastroenteritis. The present study aimed to investigate the prevalence and distribution of HAstV genotypes circulating in children < 5 years of age hospitalized with acute gastroenteritis in Chiang Mai, Thailand during 2017 to 2020. A total of 1,500 fecal specimens collected from children diagnosed with acute gastroenteritis during 2017 to 2020 were screened for HAstV by RT-PCR and identified by nucleotide sequencing. The obtained sequences were compared with the reference sequences retrieved from GenBank database and analysed by MEGA X software to assign their genotypes. Of 1,500 fecal samples, 39 (2.6%) were positive for HAstV. Of these, both classic and novel HAstV genotypes, including classic HAstV1-HAstV5, novel HAstV-MLB1, MLB2, and novel HAstV-VA2, were detected in this study. The data in this study revealed a wide variety of HAstV genotypes circulating in pediatric patients admitted to the hospitals with acute gastroenteritis in Chiang Mai, Thailand during 2017 to 2020.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hongyu Wei ◽  
Pattara Khamrin ◽  
Kattareeya Kumthip ◽  
Arpaporn Yodmeeklin ◽  
Niwat Maneekarn

AbstractHuman astrovirus (HAstV) is one of the common causes of acute gastroenteritis in children. The investigation of molecular epidemiology of HAstV is essential for monitoring the emergence and/or re-emergence of new HAstV genotypes, as well as understanding the evolution of HAstV circulating in children suffering from acute gastroenteritis. The present study aimed to investigate the prevalence and distribution of HAstVs strains circulating in children hospitalized with acute gastroenteritis in Chiang Mai, Thailand during 2017–2020. A total of 1500 fecal specimens collected from children with acute gastroenteritis were screened for HAstV by RT-PCR that targeted the partial RdRp in ORF1b and strains were characterized by sequencing and phylogenetic analysis. Of the 1500 fecal samples, 39 (2.6%) were positive for HAstV. Of these, both classic and novel HAstV genotypes, including classic HAstV1–HAstV5, novel HAstV-MLB1, MLB2, and HAstV-VA2, were detected. The data in this study revealed a high divergence of HAstV genotypes circulating in pediatric patients admitted to the hospitals with acute gastroenteritis in Chiang Mai, Thailand during 2017–2020.


Author(s):  
Noor N. Junejo ◽  
Santiago Vallasciani ◽  
Ahmad Alshammari ◽  
Hossam Aljallad ◽  
Saeed Alshahrani ◽  
...  

2015 ◽  
Vol 21 (11) ◽  
pp. 1981-1988 ◽  
Author(s):  
Shamsudeen F. Fagbo ◽  
Leila Skakni ◽  
Daniel K.W. Chu ◽  
Musa A. Garbati ◽  
Mercy Joseph ◽  
...  

2020 ◽  
Vol 19 (2) ◽  
pp. 447-453
Author(s):  
Abdulaziz Alqasim

Extra-intestinal pathogenic Escherichia coli (ExPEC) is commonly associated with causing urinary tract and bloodstream infections. Over the past two decades, the antimicrobial resistance of ExPEC has increasingly been reported [1]. Given that Saudi Arabia annually hosts mass religious events, such as Hajj, this review investigated several aspects of antimicrobial resistance of ExPEC in this country including the current prevalence of resistance and molecular epidemiology of ExPEC isolates. Generally, the overall prevalence of antibiotic resistance of ExPEC in Saudi Arabia is on increase. The current emergence of colistin resistance in ExPEC represents a major challenge to public health. Local molecular epidemiological studies have shown the dominance of E. coli sequence type 131 (E. coli ST131) over other major ExPEC STs. This is an important observation given that this clone has been associated with high multidrug resistance and extended-spectrum β-lactamases carriage. To reduce the burden of this resistance in the future, it would be crucial to avoid uncontrolled use of antibiotics in either clinical settings or animal food industry. Keywords: Extra-intestinal pathogenic Escherichia coli, Antimicrobial resistance, ST131, Saudi Arabia, Colistin resistance, Extended-spectrum β-lactamases


2001 ◽  
Vol 183 (5) ◽  
pp. 681-686 ◽  
Author(s):  
Jolán E. Walter ◽  
Douglas K. Mitchell ◽  
M. Lourdes Guerrero ◽  
Tamás Berke ◽  
David O. Matson ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document