Human bocavirus infection in children with acute respiratory tract infection in India

2010 ◽  
Vol 82 (5) ◽  
pp. 812-816 ◽  
Author(s):  
Preeti Bharaj ◽  
Wayne M. Sullender ◽  
Sushil K. Kabra ◽  
Shobha Broor
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Acute Respiratory Tract Infection ◽  
Human Bocavirus

scholarly journals Novel Human Bocavirus in Children with Acute Respiratory Tract Infection

2010 ◽  
Vol 16 (2) ◽  
pp. 324-327 ◽  
Author(s):  
Jing-rong Song ◽  
Yu Jin ◽  
Zhi-ping Xie ◽  
Han-chun Gao ◽  
Ni-guang Xiao ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Acute Respiratory Tract Infection ◽  
Human Bocavirus

scholarly journals Human bocavirus in children hospitalized for acute respiratory tract infection in Rome

2019 ◽  
Vol 16 (3) ◽  
pp. 293-298 ◽  
Author(s):  
Laura Petrarca ◽  
Raffaella Nenna ◽  
Antonella Frassanito ◽  
Alessandra Pierangeli ◽  
Greta Di Mattia ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Acute Respiratory Tract Infection ◽  
Human Bocavirus

scholarly journals Human bocavirus infection in young children with acute respiratory tract infection in Lanzhou, China

2010 ◽  
Vol 82 (2) ◽  
pp. 282-288 ◽  
Author(s):  
Li-shu Zheng ◽  
Xin-hui Yuan ◽  
Zhi-ping Xie ◽  
Yu Jin ◽  
Han-chun Gao ◽  
...  
Keyword(s):  
Tract Infection ◽  
Young Children ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Acute Respiratory Tract Infection ◽  
Human Bocavirus

scholarly journals Human bocavirus infection as a cause of severe acute respiratory tract infection in children

2015 ◽  
Vol 21 (10) ◽  
pp. 964.e1-964.e8 ◽  
Author(s):  
F.M. Moesker ◽  
J.J.A. van Kampen ◽  
A.A. van der Eijk ◽  
A.M.C. van Rossum ◽  
M. de Hoog ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Acute Respiratory Tract Infection ◽  
Human Bocavirus

scholarly journals Detection and phylogenetic analysis of Human bocavirus in children diagnosed with acute respiratory tract infection

2020 ◽  
Vol 69 (9) ◽  
pp. 1197-1202
Author(s):  
Rania Abozahra ◽  
Sarah M. Abdelhamid ◽  
Karim Khairy ◽  
Kholoud Baraka
Keyword(s):  
Phylogenetic Analysis ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Acute Respiratory Tract Infection ◽  
University Hospital ◽  
Genetic Lineage ◽  
Human Bocavirus ◽  
Igm Antibodies ◽  
Tract Infections

Introduction. Human bocavirus (HBoV) is a recently discovered parvovirus; it has been shown to be a common cause of respiratory infections and gastroenteritis in children. Since its identification, HBoV has been detected worldwide in nasopharyngeal swabs, serum and stool samples particularly those obtained from young children suffering from respiratory or gastrointestinal tract infections. Aim. The aim of this work was to determine HBoV prevalence among children with acute respiratory tract infection in Egypt, to detect the most prevalent HBoV genotype and to compare PCR and ELISA as diagnostic techniques for HBoV infection. Methods. Nasopharyngeal swabs and blood samples were obtained within the first day of admission from 75 children diagnosed with acute respiratory tract infection in El-Shatby University Hospital for Children in Alexandria, Egypt from October 2018 to March 2019. Conventional PCR was used to detect HBoV DNA, ELISA was used to detect HBoV IgM antibodies and sequencing of the VP1/2 genes was used for genotyping. Results. Seven (9.3%) of the 75 nasopharyngeal swabs obtained from patients with acute respiratory tract infection were positive for HBoV by PCR, while 5 (6.7 %) of the 75 serum samples were positive for HBoV IgM antibodies using ELISA. The correlation between PCR and ELISA results showed a highly significant association between PCR and ELISA techniques (X 2=52.041, P<0.01) and a highly significant agreement between the two methods (Kappa=81.9 %, P<0.01). Phylogenetic analysis showed that all positive samples were related to the HBoV-1 genotype. Conclusion. Human bocavirus was detected at 9.3 % prevalence in nasopharyngeal swabs obtained from children with acute respiratory tract infection. The HBoV-1 genotype was the only genotype detected, suggesting that a single genetic lineage of HBoV is circulating in Egypt. PCR and ELISA are two reliable methods for detection and diagnosis of HBoV.

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