Genetic characterization of complex inter-recombinant HIV-1 strains circulating in Spain and reliability of distinct rapid subtyping tools

2008 ◽  
Vol 80 (3) ◽  
pp. 383-391 ◽  
Author(s):  
Africa Holguín ◽  
Eva Lospitao ◽  
Marisa López ◽  
Eva Ramírez de Arellano ◽  
María José Pena ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Hiv 1

Genetic Characterization of a Novel HIV-1 CRF07_BC/CRF55_01B Recombinant Form Identified in Jiangmen, China

2020 ◽  
Vol 36 (2) ◽  
pp. 134-137 ◽  
Author(s):  
Min Han ◽  
Shixing Tang ◽  
Zhiju Li ◽  
Xin Guan ◽  
Nancai Zheng ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Recombinant Form ◽  
Hiv 1

Genetic Characterization of Viral Quasispecies in Blood and Cervical Secretions of HIV-1- and HIV-2-Infected Women

1998 ◽  
Vol 14 (16) ◽  
pp. 1473-1481 ◽  
Author(s):  
JEAN-LOUIS SANKALÉ ◽  
SOULEYMANE MBOUP ◽  
MAX E. ESSEX ◽  
PHYLLIS J. KANKI
Keyword(s):  
Genetic Characterization ◽  
Viral Quasispecies ◽  
Hiv 1

Genetic characterization of a novel unique recombinant form of HIV-1 originating from subtype A1 and C in Guangdong Province, China

2018 ◽  
Vol 164 (1) ◽  
pp. 285-290 ◽  
Author(s):  
Haohui Deng ◽  
Shuzhen Liang ◽  
Huiyuan Liu ◽  
Min Xu ◽  
Li Zhuo ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Guangdong Province ◽  
Recombinant Form ◽  
Unique Recombinant Form ◽  
Hiv 1

scholarly journals Molecular and Genetic Characterization of HIV-1 Tat Exon-1 Gene from Cameroon Shows Conserved Tat HLA-Binding Epitopes: Functional Implications

Viruses ◽  
2016 ◽  
Vol 8 (7) ◽  
pp. 196 ◽  
Author(s):  
Georges Teto ◽  
Julius Fonsah ◽  
Claude Tagny ◽  
Dora Mbanya ◽  
Emilienne Nchindap ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Functional Implications ◽  
Exon 1 ◽  
Hla Binding ◽  
Hiv 1

scholarly journals Genetic characterization of rebounding HIV-1 after cessation of highly active antiretroviral therapy

2000 ◽  
Vol 106 (7) ◽  
pp. 839-845 ◽  
Author(s):  
Linqi Zhang ◽  
Chris Chung ◽  
Bor-Shen Hu ◽  
Tian He ◽  
Yong Guo ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Highly Active Antiretroviral Therapy ◽  
Genetic Characterization ◽  
Highly Active ◽  
Hiv 1

scholarly journals HIVIntact: a python-based tool for HIV-1 genome intactness inference

Retrovirology ◽  
2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Imogen A. Wright ◽  
Michael J. Bale ◽  
Wei Shao ◽  
Wei-Shau Hu ◽  
John M. Coffin ◽  
...  
Keyword(s):  
Cell Culture ◽  
Next Generation Sequencing ◽  
Sequence Analysis ◽  
Genetic Characterization ◽  
Software Tool ◽  
Functional Cure ◽  
Manual Intervention ◽  
Generation Sequencing ◽  
Hiv 1

AbstractThe characterisation of the HIV-1 reservoir, which consists of replication-competent integrated proviruses that persist on antiretroviral therapy (ART), is made difficult by the rarity of intact proviruses relative to those that are defective. While the only conclusive test for the replication-competence of HIV-1 proviruses is carried out in cell culture, genetic characterization of genomes by near full-length (NFL) PCR and sequencing can be used to determine whether particular proviruses have insertions, deletions, or substitutions that render them defective. Proviruses that are not excluded by having such defects can be classified as genetically intact and, possibly, replication competent. Identifying and quantifying proviruses that are potentially replication-competent is important for the development of strategies towards a functional cure. However, to date, there are no programs that can be incorporated into deep-sequencing pipelines for the automated characterization and annotation of HIV genomes. Existing programs that perform this work require manual intervention, cannot be widely installed, and do not have easily adjustable settings. Here, we present HIVIntact, a python-based software tool that characterises genomic defects in NFL HIV-1 sequences, allowing putative intact genomes to be identified in-silico. Unlike other applications that assess the genetic intactness of HIV genomes, this tool can be incorporated into existing sequence-analysis pipelines and applied to large next-generation sequencing datasets.

scholarly journals Genetic characterization of the HIV-1 reservoir after Vacc-4x and romidepsin therapy in HIV-1-infected individuals

AIDS ◽  
2018 ◽  
Vol 32 (13) ◽  
pp. 1793-1802 ◽  
Author(s):  
Anni Winckelmann ◽  
Vincent Morcilla ◽  
Wei Shao ◽  
Mariane H. Schleimann ◽  
Jesper F. Hojen ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Hiv 1

scholarly journals Genetic characterization of HIV-1 epidemic in Anhui Province, China

2020 ◽  
Vol 17 (1) ◽  
Author(s):  
Dong Zhang ◽  
Jianjun Wu ◽  
Yu Zhang ◽  
Yuelan Shen ◽  
Sheying Dai ◽  
...  
Keyword(s):  
Genetic Characterization ◽  
Anhui Province ◽  
Hiv 1
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