A novel subtype of GB virus C/hepatitis G virus genotype 1 detected uniquely in patients with hemophilia in Japan

2003 ◽  
Vol 71 (3) ◽  
pp. 385-390 ◽  
Author(s):  
Hsin-Fu Liu ◽  
Ching-Wen Teng ◽  
Yoshihide Fukuda ◽  
Isao Nakano ◽  
Kazuhiko Hayashi ◽  
...  
Keyword(s):  
Genotype 1 ◽  
Virus Genotype ◽  
Hepatitis G Virus ◽  
Gb Virus C ◽  
Hepatitis G ◽  
Virus C

scholarly journals The prevalence of TT virus and GB virus C/hepatitis G virus infection in individuals with raised liver enzymes but without HBV or HCV infection in Taiwan

2002 ◽  
Vol 129 (2) ◽  
pp. 307-313 ◽  
Author(s):  
C. Y. DAI ◽  
M. L. YU ◽  
W. Y. CHANG ◽  
C. H. TSENG ◽  
C. HOU ◽  
...  
Keyword(s):  
Direct Sequencing ◽  
Male Gender ◽  
Hcv Infection ◽  
Hcv Rna ◽  
Genotype 1 ◽  
Hepatitis G Virus ◽  
Gb Virus C ◽  
Tt Virus ◽  
Hepatitis G ◽  
Virus C

The prevalence of TT virus (TTV) and GB virus-C/hepatitis G virus (GBV-C/HGV) infection and the association with raised liver function tests in 546 Taiwanese with negative HBsAg, anti-HCV and HCV RNA was elucidated. They were tested for serum alanine aminotransferase (ALT), GBV-C/HGV RNA, anti-envelope protein 2 antibody (anti-E2) and TTV DNA. Direct sequencing and phylogenetic analyses were performed on 58 isolates for TTV genotype determination. The prevalence of TTV DNA, GBV-C/HGV RNA, anti-E2 and over all GBV-C/HGV exposure was 24.9, 3.4, 8.2 and 11.1%, respectively. Using uni- and multi-variate analyses, male gender and TTV viremia were associated significantly with raised ALT values. Sixty-nine percent of TTV isolates were deduced to be TTV genotype 1 and they had significantly lower mean age than genotype non-1 isolates. In the population, raised ALT may be related to male gender and be attributable to TTV infection but not to GBV-C/HGV among individuals with no evidence of current HBV and HCV infection. TTV genotype 1 is the most prevalent genotype and associated with younger age.

High prevalence of GB virus C/hepatitis G virus genotype 3 among autochthonous Venezuelan populations

2002 ◽  
Vol 68 (3) ◽  
pp. 357-362 ◽  
Author(s):  
Carmen L. Loureiro ◽  
Roberto Alonso ◽  
Belkis A. Pacheco ◽  
María G. Uzcátegui ◽  
L. Villegas ◽  
...  
Keyword(s):  
Genotype 3 ◽  
Virus Genotype ◽  
Hepatitis G Virus ◽  
Gb Virus C ◽  
High Prevalence ◽  
Hepatitis G ◽  
Virus C

GB Virus C/Hepatitis G Virus Isolates in Japanese Haemophiliacs and their Origins

1998 ◽  
Vol 80 (08) ◽  
pp. 242-245 ◽  
Author(s):  
Yoshihide Fukuda ◽  
Tetsuo Hayakawa ◽  
Junki Takamatsu ◽  
Hidehiko Saito ◽  
Hiroaki Okamoto ◽  
...  
Keyword(s):  
Sequence Similarity ◽  
West African ◽  
Blood Products ◽  
Hepatitis G Virus ◽  
Gb Virus C ◽  
Route Of Transmission ◽  
Polymerase Chain ◽  
Hepatitis G ◽  
Virus C ◽  
Virus Isolates

SummaryJapanese haemophiliacs have been at high risk for infection with parenterally-transmissible viruses through the use of blood products, especially imported ones. Recently, novel transfusion-transmissible virus, GB virus C (GBV-C)/hepatitis G virus (HGV) were isolated. We investigated the origin and route of transmission of GBV-C/HGV isolates in haemophiliacs in Japan. GBV-C/HGV RNA was measured by nested reverse transcription polymerase chain reaction in 91 Japanese haemophiliacs. Phylogenetic analysis and genotypic grouping of GBV-C/HGV isolates in Japanese haemophiliacs were performed based on sequences in the 5’ untranslated region, and the characteristics were compared with those of reported isolates. GBV-C/HGV infection was present in 19 of 91 haemophiliacs (20.9%). Sequence analysis showed that 15 of the 19 isolates (78.9%) showed sequence similarity to a group in which mainly West African isolates have been reported. The other 4 isolates (21.1%) showed sequence similarity to Asian isolates. None of the GBV-C/HGV isolates showed sequences similar to those generally found in isolates from USA and Europe. The majority of GBV-C/HGV isolates found in Japanese haemophiliacs who are considered to have been infected by imported blood products were similar to those detected in West Africa.

GB Virus C/Hepatitis G Virus

2001 ◽  
Vol 33 (8) ◽  
pp. 572-580 ◽  
Author(s):  
Robert Halasz, Ola Weiland, Matti S
Keyword(s):  
Hepatitis G Virus ◽  
Gb Virus C ◽  
Hepatitis G ◽  
Virus C

Die Prävalenz des GB-Virus-C/Hepatitis-G-Virus in Blutspenden und seine Übertragung auf Empfänger

1998 ◽  
pp. 54-58
Author(s):  
E. Seifried ◽  
H. Bialleck ◽  
H. Weber ◽  
E. Waschk ◽  
S. Marx ◽  
...  
Keyword(s):  
Hepatitis G Virus ◽  
Gb Virus C ◽  
Hepatitis G ◽  
Virus C

Interspousal transmission of GB virus-C/hepatitis G virus: A comparison with hepatitis C virus

1997 ◽  
Vol 53 (4) ◽  
pp. 348-353 ◽  
Author(s):  
Jia-Horng Kao ◽  
Chun-Jen Liu ◽  
Pei-Jer Chen ◽  
Wendy Chen ◽  
Sheng-Chun Hsiang ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Hepatitis G Virus ◽  
Gb Virus C ◽  
Hepatitis G ◽  
Virus C

Persistent Infection Mechanism of GB Virus C/Hepatitis G Virus Differs from That of Hepatitis C Virus

Intervirology ◽  
2000 ◽  
Vol 43 (3) ◽  
pp. 139-145 ◽  
Author(s):  
Koji Orii ◽  
Eiji Tanaka ◽  
Akinori Rokuhara ◽  
Atsushi Maruyama ◽  
Tetsuya Ichijo ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Persistent Infection ◽  
Hepatitis G Virus ◽  
Gb Virus C ◽  
Infection Mechanism ◽  
Hepatitis G ◽  
Virus C
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