High prevalence of human herpesvirus 8 (HHV-8) infection in south Texas children

2002 ◽  
Vol 67 (4) ◽  
pp. 542-548 ◽  
Author(s):  
Jacques Baillargeon ◽  
Charles T. Leach ◽  
Jian-Hong Deng ◽  
Shou-Jiang Gao ◽  
Hal B. Jenson
Keyword(s):  
Human Herpesvirus ◽  
South Texas ◽  
Human Herpesvirus 8 ◽  
Herpesvirus 8 ◽  
High Prevalence

High prevalence in Central Africa of blood donors who are potentially infectious for human herpesvirus 8

Transfusion ◽  
1998 ◽  
Vol 38 (8) ◽  
pp. 771-775 ◽  
Author(s):  
L Belec ◽  
N Cancre ◽  
MC Hallouin ◽  
J Morvan ◽  
A Mohamed ◽  
...  
Keyword(s):  
Blood Donors ◽  
Central Africa ◽  
Human Herpesvirus ◽  
Human Herpesvirus 8 ◽  
Herpesvirus 8 ◽  
High Prevalence

High prevalence of Human Herpesvirus 8 in schizophrenic patients

2014 ◽  
Vol 216 (2) ◽  
pp. 192-197 ◽  
Author(s):  
Neila Hannachi ◽  
Yousri El Kissi ◽  
Samar Samoud ◽  
Jaafar Nakhli ◽  
Leila Letaief ◽  
...  
Keyword(s):  
Human Herpesvirus ◽  
Human Herpesvirus 8 ◽  
Herpesvirus 8 ◽  
High Prevalence ◽  
Schizophrenic Patients

High prevalence of human herpesvirus 8 in a Tunisian sample of Schizophrenic patients

2011 ◽  
Vol 26 (S2) ◽  
pp. 1375-1375 ◽  
Author(s):  
Y. El Kissi ◽  
N. Hannach ◽  
S. Gaabout ◽  
S. Samoud ◽  
M. Ayachi ◽  
...  
Keyword(s):  
Human Herpesvirus ◽  
Severity Of Illness ◽  
Immunofluorescence Assay ◽  
Human Herpesvirus 8 ◽  
Professional Activity ◽  
Healthy Controls ◽  
Herpesvirus 8 ◽  
Number Of Children ◽  
High Prevalence ◽  
Schizophrenic Patients

BackgroundThe prevalence of Human Herpesvirus 8 (HHV8) has never been investigated in schizophrenic patients.ObjectiveThis study aimed to assess the prevalence of HHV8 serum antibodies in schizophrenic patients and in healthy controls.MethodsDuring a 24 months period, we consecutively enrolled 108 patients meeting DSM-IV criteria of schizophrenia, in psychiatry department of Sousse Farhat Hached hospital (Tunisia). We also enrolled 108 controls among consenting blood donors. They were age and sex matched and free from any psychotic disorder as screened by MINI-Plus.Psychopathology and severity were measured using PANSS, BPRS, SANS, SAPS and CGI. Sera samples were obtained from patients and controls and then analyzed for the presence of anti-HHV8 antibodies (anti-HHV8) using a sensitive indirect immunofluorescence assay to latent and lytic HHV8 antigens.ResultsA significantly higher prevalence of anti-HHV8 in schizophrenic patients than in healthy controls was found (28.7% vs. 14.8%, p = 0.01). Marital status, educational level, professional activity, poverty, promiscuity, number of children, sexual behavior or presence of risk factors of blood transmission were not associated with HHV8 prevalence (p > 0.05). However, among schizophrenic patients, HHV8 prevalence was statically associated with positive symptoms (SAPS score) (p = 0.01) and the severity of illness (CGI score) (p = 0.02).ConclusionTo our knowledge, this would be the first report of high HHV8 prevalence in schizophrenic patients, which support the role of this virus in the pathogenesis of schizophrenia. To go on further with this hypothesis, more investigations of HHV8 in schizophrenia are needed.

scholarly journals Confirming high prevalence of human herpesvirus 8 infection in chronic kidney disease patients in Sao Paulo, Brazil

2008 ◽  
Vol 2 (1) ◽  
pp. 93-94 ◽  
Author(s):  
M. C. Magri ◽  
M. E. F. Canziani ◽  
S. A. Draibe ◽  
E. Santos-Fortuna ◽  
A. C. de-Araujo
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Human Herpesvirus ◽  
Sao Paulo ◽  
Human Herpesvirus 8 ◽  
São Paulo ◽  
Herpesvirus 8 ◽  
High Prevalence

scholarly journals High Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia

1998 ◽  
Vol 177 (6) ◽  
pp. 1715-1718 ◽  
Author(s):  
Antonio Angeloni ◽  
Lee Heston ◽  
Stefania Uccini ◽  
Maria Caterina Sirianni ◽  
Francesca Cottoni ◽  
...  
Keyword(s):  
Kaposi's Sarcoma ◽  
Human Herpesvirus ◽  
Kaposi’S Sarcoma ◽  
Human Herpesvirus 8 ◽  
Herpesvirus 8 ◽  
High Prevalence

scholarly journals Increasing seroprevalence of Human herpesvirus 8 (HHV-8) with age confirms HHV-8 endemicity in Amazon Amerindians from Brazil

2005 ◽  
Vol 86 (9) ◽  
pp. 2433-2437 ◽  
Author(s):  
A. M. G. Cunha ◽  
A. Caterino-de-Araujo ◽  
S. C. B. Costa ◽  
E. Santos-Fortuna ◽  
N. C. A. Boa-Sorte ◽  
...  
Keyword(s):  
Familial Aggregation ◽  
Horizontal Transmission ◽  
Age Groups ◽  
Human Herpesvirus ◽  
Human Herpesvirus 8 ◽  
Serum Samples ◽  
Isolated Populations ◽  
Herpesvirus 8 ◽  
High Prevalence ◽  
Amerindian Tribes

Human herpesvirus 8 (HHV-8) seroprevalences were determined in two isolated Amazon Amerindian tribes, according to age, gender and familial aggregation. Plasma and serum samples obtained from 982 Amazon Amerindians (664 Tiriyó and 318 Waiampi) were tested for antibodies against lytic and latent HHV-8 antigens by using ‘in-house’ immunofluorescence assays. Overall, HHV-8 seroprevalence was 56·8 % (57·4 % in the Tiriyó tribe and 55·7 % in the Waiampi tribe). Seroprevalence was independent of gender and increased linearly with age: it was 35·0 % among children aged 2–9 years, 51·4 % in adolescents (10–19 years), 72·9 % in adults and 82·3 % in adults aged >50 years. Interestingly, 44·4 % of children under 2 years of age were HHV-8-seropositive. No significant differences in seroprevalence between tribes and age groups were detected. It is concluded that HHV-8 is hyperendemic in Brazilian Amazon Amerindians, with vertical and horizontal transmission during childhood, familial transmission and sexual contact in adulthood contributing to this high prevalence in these isolated populations.

scholarly journals Recombination in human herpesvirus-8 strains from Uganda and evolution of the K15 gene

2001 ◽  
Vol 82 (10) ◽  
pp. 2393-2404 ◽  
Author(s):  
Dorothy N. Kakoola ◽  
Julie Sheldon ◽  
Naomi Byabazaire ◽  
Rory J. Bowden ◽  
Edward Katongole-Mbidde ◽  
...  
Keyword(s):  
Recombination Event ◽  
Blood Donors ◽  
Human Herpesvirus ◽  
Human Herpesvirus 8 ◽  
Single Strain ◽  
Herpesvirus 8 ◽  
Immunodeficiency Virus ◽  
High Prevalence ◽  
Limited Variation ◽  
Hiv Negative

Human herpesvirus-8 (HHV-8) is believed to be the aetiological agent of Kaposi’s sarcoma (KS). KS accounts for half the reported cancer cases in Uganda, and occurs in endemic and epidemic [human immunodeficiency virus (HIV)-associated] forms. We confirmed a high prevalence (74%) of HHV-8 antibodies in 114 HIV-negative Ugandan blood donors, and characterized the genomes of HHV-8 strains present in 30 adult Ugandan KS patients. Phylogenetic analysis of the uniquely variable K1 gene indicated that the majority of KS patients were infected by the B subtype of HHV-8, several by the A5 subtype, and one by a variant of the C subtype. Sequence analysis of nine strains at several other genome loci spaced out across the genome indicated that five are recombinants between subtypes when considered independently of previously published definitions of parental (unrecombined) genotypes. When previously published parental genotypes were taken into account, seven of the nine strains appeared to be recombinants. Analysis of the K15 gene, which exists in HHV-8 in two highly diverged alleles, indicated that the P allele predominates, with only a single strain bearing the M allele. Divergence between the M allele in the latter strain and that in the previously sequenced BC1 strain is at least as great as that between representatives of the P allele. This indicates that introduction of the M allele into extant HHV-8 subtypes did not occur by a single, relatively recent recombination event as was concluded from a previous study in which very limited variation in the M allele was reported.

P.1.b.012 High prevalence of human herpesvirus 8 in a tunisian sample of schizophrenic patients

2010 ◽  
Vol 20 ◽  
pp. S233-S234
Author(s):  
Y. El Kissi ◽  
N. Hannachi ◽  
S. Samoud ◽  
S. Gaabout ◽  
M. Ayachi ◽  
...  
Keyword(s):  
Human Herpesvirus ◽  
Human Herpesvirus 8 ◽  
Herpesvirus 8 ◽  
High Prevalence ◽  
Schizophrenic Patients
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