Charge state assignment from schiff-base adducts in low resolution electrospray mass spectra of protein mixtures and dissociation products

1995 ◽  
Vol 30 (1) ◽  
pp. 119-123 ◽  
Author(s):  
Ziqiang Guan ◽  
Victoria L. Campbell ◽  
David A. Laude
Keyword(s):  
Schiff Base ◽  
Charge State ◽  
Mass Spectra ◽  
Low Resolution ◽  
State Assignment

Use of an Artificial Immune System Derived Method for the Charge State Assignment of Small-Molecule Mass Spectra

2012 ◽  
Vol 84 (17) ◽  
pp. 7436-7439 ◽  
Author(s):  
David P. A. Kilgour ◽  
C. Logan Mackay ◽  
Patrick R. R. Langridge-Smith ◽  
Peter B. O’Connor
Keyword(s):  
Immune System ◽  
Charge State ◽  
Small Molecule ◽  
Mass Spectra ◽  
Artificial Immune System ◽  
Artificial Immune ◽  
State Assignment

Interpreting the Charge State Assignment in Electrospray Mass Spectra of Bioparticles

2011 ◽  
Vol 83 (6) ◽  
pp. 1960-1968 ◽  
Author(s):  
Yao-Hsin Tseng ◽  
Charlotte Uetrecht ◽  
Albert J. R. Heck ◽  
Wen-Ping Peng
Keyword(s):  
Charge State ◽  
Mass Spectra ◽  
State Assignment

scholarly journals Synthesis, characterization and biological activity of a Schiff base derived from o-amino benzoic acid and its Co(II), Cd(II) and Ni(II) complexes

2020 ◽  
Vol 11 (1) ◽  
pp. 15-20
Author(s):  
Tasneem Ibrahim Hussein ◽  
Musa Abduelrahman Ahmed ◽  
Ismail Adam Arbab ◽  
Awad Salim Ibrahim ◽  
Mohamed Al-Bratty ◽  
...  
Keyword(s):  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Mass Spectra ◽  
Free Ligand ◽  
Antimicrobial Properties ◽  
Proton Nuclear Magnetic Resonance ◽  
Complexing Agent ◽  
Diffusion Technique ◽  
Nuclear Magnetic Resonance Spectra

Equimolar amounts of imidazoleacetophenone and 2-aminobenzoic acid were combined together and the Schiff base 4(1H-imidazole-yl)acetophenoneanthranilic acid was prepared as a new bidentate complexing agent. The synthesized ligand was reacted with cobalt(II), cadmium(II), and nickel(II) ions yielding air stable complexes. For quantification and characterization purposes, elemental analysis, infrared spectra, electronic spectra, proton nuclear magnetic resonance spectra and mass spectra studies were carried out on the obtained complexes and ligand. Thermogravimetric analysis and magnetic susceptibility measurements were also used for characterization. The ligand IR spectrum showed that the ligand acts as a bidentate coordinates to the metal ions through the nitrogen and oxygen atoms.Measurements of magnetic susceptibility for Ni(II) and Co(II) complexes were found to be 3.4 and 3.8 B.M., respectively, in the range normal for the octahedral geometry. The conductivity measurements revealed that the chelates are non-electrolytes. An in vitro antimicrobial investigation was also carried out for the free ligand and its metal complexes against a number of bacterial and fungal strains, to assess their antimicrobial properties by diffusion technique. Antimicrobial activity of the prepared complexes showed higher activity than the free ligand.

Diazabenzenes. I. Synthesis of some t-butylpyrazines and their N-oxides

1972 ◽  
Vol 25 (12) ◽  
pp. 2671 ◽  
Author(s):  
RF Evans ◽  
KN Mewett
Keyword(s):  
Steric Hindrance ◽  
Mass Spectra ◽  
Ammonium Acetate ◽  
Spectroscopic Properties ◽  
Iron Pentacarbonyl ◽  
Membered Ring ◽  
Low Resolution ◽  
Butyl Lithium ◽  
Pyrazine Ring ◽  
Resolution Mass

Steric hindrance prevented formation of tetra-t-butylpyrazine either when pivaloin was heated with ammonium acetate or when pivalil monooxime was reduced with zinc and alkali. Diminution of the steric hindrance of the t-butyl groups by masking them by incorporation into a seven-membered ring containing sulphur was of no avail. 2,5-Di-t- butylpyrazine resulted from the analogous reduction of t-butyl-glyoxal dioxime and could be converted into its N-oxide and N,N?-dioxide. t- Butyl-lithium reacted with the pyrazine and the mono-N-oxide to give a mixture of products including 2,3,5-tri-t-butylpyrazine whose spectroscopic properties suggested a buckling of the pyrazine ring. Benzonitrile and diphenylacetylene reacted independently in the presence of iron pentacarbonyl and gave, inter alia, 2,4,6-triphenyl- 1,3,5-triazine and hexaphenylbenzene respectively. ��� The most prominent features of the low resolution mass spectra of these pyrazines and some of their precursors are discussed and rationalized.

scholarly journals Synthesis, characterization, and antimicrobial activities of novel double-armed benzo-15-crown-5 and their sodium and potassium complexes

2020 ◽  
pp. 174751982093226
Author(s):  
Öznur Şener Cemaloğlu ◽  
Hatice Ogutcu ◽  
Zeliha Hayvalı
Keyword(s):  
Schiff Base ◽  
Crown Ether ◽  
Mass Spectra ◽  
Sodium Perchlorate ◽  
Antimicrobial Activities ◽  
Pathogenic Microorganisms ◽  
Inhibitory Effects ◽  
Antibacterial Effects ◽  
Sodium And Potassium ◽  
C Nmr

New aldehyde- and halogen- (Cl, Br, I) substituted double-armed benzo-15-crown-5 derivatives are synthesized by the reactions of 4′,5′-bis(bromomethyl)benzo-15-crown-5 with 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, or 5-iodosalicylaldehyde. The sodium and potassium complexes are obtained by reaction of crown ether with sodium perchlorate and potassium iodide, respectively. Novel Schiff base compounds containing three groups of benzo-15-crown-5 are obtained from the condensation of aldehydes with 4′-aminobenzo-15-crown-5. The structures of all compounds are elucidated by elemental analysis, 1H, 13C NMR, IR, and mass spectra. The antifungal and antibacterial effects of the synthesized ligands are evaluated against pathogenic microorganisms and show varying degrees of inhibitory effects against the growth of different pathogenic strains. Graphical abstract

Sign in / Sign up

Export Citation Format

Share Document