scholarly journals Comparing four volumetric modulated arc therapy beam arrangements for the treatment of early‐stage prostate cancer

2014 ◽  
Vol 61 (2) ◽  
pp. 91-101 ◽  
Author(s):  
Craig A. Elith ◽  
Shane E. Dempsey ◽  
Helen M. Warren‐Forward
2014 ◽  
Vol 61 (4) ◽  
pp. 261-266 ◽  
Author(s):  
Craig A. Elith ◽  
Shane E. Dempsey ◽  
Fred Cao ◽  
Afrooz Farshadi ◽  
Helen M. Warren‐Forward

Author(s):  
Craig A. Elith ◽  
Shane E. Dempsey ◽  
Helen M. Warren-Forward

AbstractAimThis study compared the acute toxicities reported during radiotherapy treatment using either intensity-modulated radiation therapy (IMRT) or volumetric-modulated arc therapy (VMAT) to deliver a moderate hypo-fractionated treatment for early-stage prostate cancer.Material and methodsAcute toxicities are routinely reported at the clinical site for all patients using the Common Terminology Criteria for Adverse Events. Toxicity assessment is performed on day 1 of treatment, then once weekly thereafter. The recorded toxicities of 40 cases treated with five-field IMRT, and 32 cases treated using VMAT were retrospectively compared. All cases were prescribed 73·68 Gy in 28 fractions. Eight symptoms were assessed; diarrhoea, proctitis, fatigue, pain, dermatitis, urinary frequency, urinary retention and urinary tract pain.ResultsIn terms of the overall toxicity recorded, VMAT was shown to reduce the toxicities of dermatitis, fatigue, pain and urinary frequency (p<0·05). Using IMRT, grade 2 toxicities were reported for proctitis, pain, urinary frequency, urinary retention and urinary tract pain. Using VMAT, grade 2 toxicities were reported for urinary frequency and urinary retention.FindingsThe research reported here is one of the first publications to demonstrate that VMAT is associated with decreased toxicities compared with IMRT for the treatment of early-stage prostate cancer.


2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Vincent Wing Cheung Wu ◽  
Man In Pun ◽  
Cho Pan Lam ◽  
To Wing Mok ◽  
Wah Wai Mok

This study compared the performance of volumetric modulated arc therapy (VMAT) techniques: single arc volumetric modulated arc therapy (SA-VMAT) and double arc volumetric modulated arc therapy (DA-VMAT) with the static beam conventional intensity modulated radiotherapy (C-IMRT) for non-small-cell lung carcinoma (NSCLC). Twelve stage I and II NSCLC patients were recruited and their planning CT with contoured planning target volume (PTV) and organs at risk (OARs) was used for planning. Using the same dose constraints and planning objectives, the C-IMRT, SA-VMAT, and DA-VMAT plans were optimized. C-IMRT consisted of 7 static beams, while SA-VMAT and DA-VMAT plans consisted of one and two full gantry rotations, respectively. No significant difference was found among the three techniques in target homogeneity and conformity. Mean lung dose in C-IMRT plan was significantly lower than that in DA-VMAT plan P=0.04. The ability of OAR sparing was similar among the three techniques, with no significant difference in V20, V10, or V5 of normal lungs, spinal cord, and heart. Less MUs were required in SA-VMAT and DA-VMAT. Besides, SA-VMAT required the shortest beam on time among the three techniques. In treatment of early stage NSCLC, no significant dosimetric superiority was shown by the VMAT techniques over C-IMRT and DA-VMAT over SA-VMAT.


2014 ◽  
Vol 113 (3) ◽  
pp. 385-391 ◽  
Author(s):  
Antonella Fogliata ◽  
Francesca Belosi ◽  
Alessandro Clivio ◽  
Piera Navarria ◽  
Giorgia Nicolini ◽  
...  

2014 ◽  
Vol 45 (2) ◽  
pp. 162
Author(s):  
Krista Bota ◽  
Stewart Gaede ◽  
Scott Karnas ◽  
Eugene Wong ◽  
Wong Eugene ◽  
...  

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