MRA of the Supraaortic Vasculature: Comparison of Gadobutrol and Gadoterate Meglumine at 1. 5 T

2021 ◽  
Author(s):  
John W. Cerne ◽  
Ashitha Pathrose ◽  
Alyssa M. Singer ◽  
Jackson E. Moore ◽  
Ali Serhal ◽  
...  
Keyword(s):  
Gadoterate Meglumine

scholarly journals A Pharmacokinetics, Efficacy, and Safety Study of Gadoterate Meglumine in Pediatric Subjects Aged Younger Than 2 Years

2018 ◽  
Vol 53 (2) ◽  
pp. 70-79 ◽  
Author(s):  
Mario Scala ◽  
Meriam Koob ◽  
Sophie de Buttet ◽  
Philippe Bourrinet ◽  
Mathieu Felices ◽  
...  
Keyword(s):  
Efficacy And Safety ◽  
Safety Study ◽  
Gadoterate Meglumine

scholarly journals Evaluation of 3.0-T MRI Brain Signal after Exposure to Gadoterate Meglumine in Women with High Breast Cancer Risk and Screening Breast MRI

Radiology ◽  
2019 ◽  
Vol 293 (3) ◽  
pp. 523-530 ◽  
Author(s):  
Barbara Bennani-Baiti ◽  
Barbara Krug ◽  
Daniel Giese ◽  
Martin Hellmich ◽  
Sophie Bartsch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Breast Mri ◽  
Mri Brain ◽  
Gadoterate Meglumine ◽  
3.0 T ◽  
High Breast Cancer Risk ◽  
3.0 T Mri

A Structured Survey on Adverse Events Occurring Within 24 Hours After Intravenous Exposure to Gadodiamide or Gadoterate Meglumine

2019 ◽  
Vol 54 (4) ◽  
pp. 191-197 ◽  
Author(s):  
Marco Parillo ◽  
Martina Sapienza ◽  
Francesco Arpaia ◽  
Francesca Magnani ◽  
Carlo Augusto Mallio ◽  
...  
Keyword(s):  
Adverse Events ◽  
Gadoterate Meglumine

One-year Retention of Gadolinium in the Brain: Comparison of Gadodiamide and Gadoterate Meglumine in a Rodent Model

Radiology ◽  
2018 ◽  
Vol 288 (2) ◽  
pp. 424-433 ◽  
Author(s):  
Philippe Robert ◽  
Stefanie Fingerhut ◽  
Cécile Factor ◽  
Véronique Vives ◽  
Justine Letien ◽  
...  
Keyword(s):  
Rodent Model ◽  
Gadoterate Meglumine ◽  
One Year ◽  
The Brain

The switch from Gd-DTPA to Gd-DOTA is not associated with decrease of the T1 signal intensity of the pallidus and dentate in a pediatric population

2020 ◽  
pp. 028418512092792
Author(s):  
Pietro Gulino ◽  
Andrea Bianchi ◽  
Stefano Diciotti ◽  
Alessandra Scionti ◽  
Lapo Sali ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Gray Matter ◽  
Signal Intensity ◽  
Pediatric Patients ◽  
Spin Echo ◽  
Pediatric Population ◽  
Rate Of Change ◽  
Middle Cerebellar Peduncle ◽  
Gadoterate Meglumine ◽  
Cerebellar Peduncle

Background The switch from the linear gadolinium-based contrast agent (GBCA) gadopentate dimeglumine (Gd_DTPA) to the macrocyclic GBCA gadobutrol is associated with a decrease of the T1 signal intensity (SI) in brain gray matter nuclei. The effects of the switch to other macrocyclic GBCAs are not yet established. Purpose To explore the effects of switching from Gd-DTPA to the macrocyclic GBCA gadoterate meglumine (Gd-DOTA) in pediatric patients. Material and Methods We measured the pallidus/middle cerebellar peduncle (MCP) SI ratio and the dentate/MCP SI ratio in pre-contrast sagittal T1-weighted spin-echo images in nine patients who had received ≥6 administrations of Gd-DTPA and then of Gd-DOTA, in 18 patients who had received ≥6 administrations of Gd-DOTA alone, and in nine age-matched controls without prior GBCA administrations. Serial assessment was performed in patients who switched from Gd-DTPA to Gd-DOTA. Finally, the rate of change of pallidal/MCP and dentate/MCP SI ratios between the first and last Gd-DOTA administrations was compared. Results The pallidal/MCP and dentate/MCP SI ratios were ( P < 0.05) higher in patients with prior Gd-DTPA and Gd-DOTA administrations compared to the controls. After the switch, the pallidal/MCP SI ratio increased in nine patients and the dentate/MCP ratio in seven patients. The rate of change of pallidal/MCP SI ratio after Gd-DOTA was higher ( P < 0.01) in patients who had previously received Gd-DTPA (mean 2.89 ± 2.6%) than in patients who had received Gd-DOTA alone (mean 0.53 ± 0.89%). Conclusion T1 SI in gray matter nuclei does not decrease after switching from Gd-DTPA to Gd-DOTA. The switch effects from Gd-DTPA to each macrocyclic GBCA should be individually evaluated.

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