Q‐Dixon and GRAPPATINI T2 Mapping Parameters: A Whole Spinal Assessment of the Relationship Between Osteoporosis and Intervertebral Disc Degeneration

2021 ◽  
Author(s):  
Xiangwen Li ◽  
Yuxue Xie ◽  
Rong Lu ◽  
Yuyang Zhang ◽  
Qing Li ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
T2 Mapping ◽  
Mapping Parameters ◽  
The Relationship

scholarly journals Feasibility of T2 Mapping and Magnetic Transfer Ratio for Diagnosis of Intervertebral Disc Degeneration at the Cervicothoracic Junction: A Pilot Study

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Chao Zhang ◽  
Yuan Lin ◽  
Zhihua Han ◽  
Liang Gao ◽  
Ruipeng Guo ◽  
...  
Keyword(s):  
Relaxation Time ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
T2 Mapping ◽  
T2 Relaxation Time ◽  
T2 Relaxation ◽  
Cervicothoracic Junction ◽  
Magnetic Transfer ◽  
Pfirrmann Grade

Background. Intervertebral disc degeneration (IDD) at the cervicothoracic junction of spine is clinically relevant, however, little attention had been paid. T2 mapping and magnetic transfer ratio (MTR) are useful magnetic resonance imaging (MRI) techniques to quantitatively evaluate IDD, revealing the biochemical changes within the intervertebral disc. To compare T2 mapping with MTR imaging regarding their accuracy to quantitatively diagnose intervertebral disc degeneration at the cervicothoracic junction, influences of anatomical level, gender, age, and Pfirrmann grade of T2 relaxation time values and MTR values were evaluated. Methods. Sixty-seven patients with neck and upper back pain were included and examined with both T2 mapping and MTR imaging. The Pfirrmann grade, T2 relaxation time values, and MTR value of each disc between C7 and T3 were measured. Differences were investigated among different segmental levels, genders, age ranges, and Pfirrmann grades. The diagnostic accuracy of both MRI techniques was compared using the receiver operating characteristic (ROC) curves. Results. No significant difference was detected comparing T2 relaxation time values or MTR values among different anatomical levels, genders, and segmental levels. And we generally found that T2 relaxation time values decreased, while MTR value increased with increasing age. Importantly, we demonstrated the significant correlation between either T2 relaxation time values or MTR value and Pfirrmann grade. Conclusion. We proved the better accuracy of T2 mapping over MTR imaging to quantitatively evaluate the intervertebral disc degeneration of the cervicothoracic junction.

scholarly journals The relationship between Modic changes and intervertebral disc degeneration

2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Juhani H. Määttä ◽  
Alex MacGregor ◽  
Jaro Karppinen ◽  
Frances M. K. Williams
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Modic Changes ◽  
The Relationship

scholarly journals The Dual Effect of Abnormal Serum Uric Acid on Intervertebral Disc Degeneration

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Ming Yang ◽  
Naiguo Wang ◽  
Wentao Zhang ◽  
Tianze Sun ◽  
Dan Zhang ◽  
...  
Keyword(s):  
Uric Acid ◽  
Intervertebral Disc ◽  
Serum Uric Acid ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Total Population ◽  
Multiple Logistic Regression Analysis ◽  
Significant Difference ◽  
Baseline Characteristics ◽  
The Relationship

An abnormal serum uric acid (SUA) level is associated with many diseases. To our knowledge, there is no research on the association between SUA and intervertebral disc degeneration (IDD). The purpose of this study was to determine the relationship between SUA and IDD. From June 2011 to July 2020, 691 patients undergoing surgery for lumbar disc herniation (LDH) were included in the LDH group, and 684 patients who underwent endoscopic surgery for knee trauma were included in the non-LDH group. We examined the baseline characteristics of all these patients and divided the SUA level into 10 groups according to the percentiles in males, females, and the total population. Subsequently, the relationship between the SUA level and IDD was further analyzed. There was no statistically significant difference in the baseline characteristics of the two groups ( p > 0.05 ). Among the 10 groups, the LDH rate was higher at both lower and higher SUA levels. In multiple logistic regression analysis, after adjustment for age, sex, body mass index, smoking, and drinking, when the SUA level was <20% or >80%, compared with 60–80%, the odds ratio (OR) and 95% confidence interval (CI) of LDH of the total population were 1.821 (1.125–2.946) and 1.701 (1.186–2.438), respectively, and in the males, they were 1.922 (1.169–3.161) and 2.800 (1.766, 4.439), respectively. In females, when the SUA was <20%, there was a higher LDH rate ( OR = 1.951 , 95% CI 1.091-3.486). The present study suggests that there is a U-shaped relationship between SUA and IDD, being particularly prominent among male. Lower and higher SUA level may be risk factors for IDD.

scholarly journals Axial T2* mapping in intervertebral discs: a new technique for assessment of intervertebral disc degeneration

2012 ◽  
Vol 22 (9) ◽  
pp. 2013-2019 ◽  
Author(s):  
Sven Hoppe ◽  
Sebastian Quirbach ◽  
Tallal C. Mamisch ◽  
Fabian G. Krause ◽  
Stefan Werlen ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
T2 Mapping ◽  
Intervertebral Discs ◽  
New Technique ◽  
A New Technique

MRI T2* mapping correlates with biochemistry and histology in intervertebral disc degeneration in a large animal model

2014 ◽  
Vol 24 (9) ◽  
pp. 1935-1943 ◽  
Author(s):  
Suzanne E. L. Detiger ◽  
Roderick M. Holewijn ◽  
Roel J. W. Hoogendoorn ◽  
Barend J. van Royen ◽  
Marco N. Helder ◽  
...  
Keyword(s):  
Animal Model ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
T2 Mapping ◽  
Large Animal Model ◽  
Large Animal

scholarly journals The Relationship between HELQ Expression and Intervertebral Disc Degeneration

2016 ◽  
Vol 6 (1_suppl) ◽  
pp. s-0036-1582627-s-0036-1582627
Author(s):  
Shanhu Huang ◽  
Yu Zhang ◽  
Zhili Liu ◽  
Jiaming Liu
Keyword(s):  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
The Relationship
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