scholarly journals Right/Left Ventricular Blood Pool T2 Ratio as an Innovative Cardiac MRI Screening Tool for the Identification of Left‐to‐Right Shunts in Patients With Right Ventricular Disease

2021 ◽  
Author(s):  
Tilman Emrich ◽  
Veronica Bordonaro ◽  
U. Joseph Schoepf ◽  
Aniela Petrescu ◽  
Gabrielle Young ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Cardiac Mri ◽  
Screening Tool ◽  
Blood Pool ◽  
Left Ventricular

scholarly journals SAT0276 CARDIAC MAGNETIC RESONANCE IMAGING IN PATIENTS WITH BEHCET’S DISEASE: A PILOT STUDY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1082.1-1083
Author(s):  
A. A. Ahmed ◽  
S. Tharwat ◽  
N. M. Batouty ◽  
S. D. Abd El-Halim
Keyword(s):  
Magnetic Resonance Imaging ◽  
Right Ventricular ◽  
Behçet’S Disease ◽  
Cardiac Mri ◽  
Behcet’S Disease ◽  
Cardiac Involvement ◽  
Behçet's Disease ◽  
Left Ventricular ◽  
Resonance Imaging ◽  
Behcet's Disease

Background:Behçet’s disease is a multisystemic vasculitis characterized by mucocutaneous, ocular, arthritic, and vascular manifestations.[1] However, the incidence and nature of cardiac involvement in Behcet’s disease have not been clearly documented yet.Objectives:This study aimed to assess the cardiac involvement in patients with Behçet’s disease using cardiac magnetic resonance imaging (MRI).Methods:This cross -sectional descriptive study was carried out on thirty consecutive patients with Behçet’s disease (21 males,9 females) with mean age 32.3±8.9 years and with no evidence of cardiac disease. They underwent cardiac MRI to determine morphological and functional changes of the heart and to detect areas of hyperenhancement after IV administration of gadolinium.Results:At least one abnormality on cardiac MRI was observed in 20/30 patients (66.67%). Myocardial oedema was observed in 3 patients (10.0%) and late gadolinium enhancement in only 1 patient (3.3%). Pericardial effusion was found in 3 patients (10.0 %), global hypokinesia in 6 patients (20.0%) and intra-cardiac thrombosis in only 1 patient (3.3%). Pulmonary artery was dilated in 4 patients (13.3%). Left ventricular and right ventricular end diastolic volume were altered in 4 patients (13.3 %) and 7 patients (23.3%) respectively. Also, left ventricular and right ventricular end systolic volume were abnormal in7 patients (23.3%) and 5 patients (16.7%) respectively. Moreover, there was aortic valve regurge in 2 patients (6.7%), tricuspid valve regurge in 9 patients (30%), and mitral valve regurge in 9 patients (30%).Dilated left main coronary artery in 2 patients (6.7%) and arythmogenic right ventricular dysplasia in only one patient 1 patient (3.3%).Conclusion:Behçet’s disease may cause cardiac abnormalities without clinical manifestations and cardiac MRI may represent a tool for early detection of these subtle abnormalities.References:[1]Geri, G., et al., Spectrum of cardiac lesions in Behçet disease: a series of 52 patients and review of the literature. Medicine, 2012.91(1): p. 25-34.Figure 1.Cardiac MRI in 32 year-old female patient with Behçet’s disease for 3 years.Acknowledgments: :The authors would like to acknowledge Ahmed El Bahy for his assistance with this studyDisclosure of Interests:None declared

Rapid cardiac MRI protocol for cardiac assessment in paediatric and young adult patients undergoing haematopoietic stem cell transplant: a feasibility study

2021 ◽  
pp. 1-6
Author(s):  
Thomas D. Ryan ◽  
Ryan A. Moore ◽  
Sean M. Lang ◽  
Philip Khoury ◽  
Christopher E. Dandoy ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Right Ventricular ◽  
Cell Transplantation ◽  
Feasibility Study ◽  
Cardiac Mri ◽  
Haematopoietic Stem Cell Transplantation ◽  
Left Ventricular ◽  
Haematopoietic Stem Cell ◽  
Mri Protocol

Abstract Background: Haematopoietic stem cell transplantation is an important and effective treatment strategy for many malignancies, marrow failure syndromes, and immunodeficiencies in children, adolescents, and young adults. Despite advances in supportive care, patients undergoing transplant are at increased risk to develop cardiovascular co-morbidities. Methods: This study was performed as a feasibility study of a rapid cardiac MRI protocol to substitute for echocardiography in the assessment of left ventricular size and function, pericardial effusion, and right ventricular hypertension. Results: A total of 13 patients were enrolled for the study (age 17.5 ± 7.7 years, 77% male, 77% white). Mean study time was 13.2 ± 5.6 minutes for MRI and 18.8 ± 5.7 minutes for echocardiogram (p = 0.064). Correlation between left ventricular ejection fraction by MRI and echocardiogram was good (ICC 0.76; 95% CI 0.47, 0.92). None of the patients had documented right ventricular hypertension. Patients were given a survey regarding their experiences, with the majority both perceiving that the echocardiogram took longer (7/13) and indicating they would prefer the MRI if given a choice (10/13). Conclusion: A rapid cardiac MRI protocol was shown feasible to substitute for echocardiogram in the assessment of key factors prior to or in follow-up after haematopoietic stem cell transplantation.

Cardiac MRI is Superior to Gated Blood Pool Imaging in the Assessment of Left Ventricular Function in Patients Post-cardiac Transplantation

2010 ◽  
Vol 19 (7) ◽  
pp. 400-405 ◽  
Author(s):  
Wendy E. Strugnell ◽  
Christian R. Hamilton-Craig ◽  
Temeeka A. Parry ◽  
Harold J.G. Bartlett ◽  
Richard E. Slaughter
Keyword(s):  
Left Ventricular Function ◽  
Ventricular Function ◽  
Cardiac Mri ◽  
Cardiac Transplantation ◽  
Blood Pool ◽  
Left Ventricular ◽  
Gated Blood Pool Imaging ◽  
Blood Pool Imaging ◽  
Gated Blood Pool

scholarly journals Isolated Right Ventricular Myocarditis: Rarely Reported Pathology

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Hafeez Ul Hassan Virk ◽  
Muhammad Bilal Munir
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Right Ventricular ◽  
Ventricular Function ◽  
Cardiac Mri ◽  
Early Recognition ◽  
Early Stage ◽  
Left Ventricular ◽  
Mri Findings ◽  
Artery Disease

Objective.Preventing the morbidity and mortality from isolated right ventricular myocarditis by its early recognition and treatment.Background. The clinical presentation of myocarditis ranges from nonspecific systemic symptoms (fever, myalgia, palpitations, or exertional dyspnea) to fulminant cardiac failure and sudden death. In our case, echocardiography raised the possibility of myocarditis at an early stage, although the signs and symptoms did not indicate right ventricular disease. Review of the literature showed only 4 previous reports, all diagnosed at autopsy, in which diagnosis was not suspected in vivo.Design/Methods. We are reporting case of a 23-year-old male with no past medical history who presented to emergency room with a nonexertional sharp left sided chest pain. Diagnostic tests were conducted, which revealed elevated troponins, decreased right ventricular ejection function but preserved left ventricular function, and no evidence of coronary artery disease.Results. A diagnosis of isolated right ventricular myocarditis was made on the basis of clinical, echocardiographic, and cardiac MRI findings.Conclusions. Isolated right ventricular myocarditis should be suspected in a patient with depressed right ventricular function without left ventricular involvement on echocardiography and cardiac MRI, elevated cardiac enzymes, and no evidence of coronary artery disease.

scholarly journals Subclinical Changes in Cardiac Functional Parameters as Determined by Cardiovascular Magnetic Resonance (CMR) Imaging in Sleep Apnea and Snoring: Findings from UK Biobank

Medicina ◽  
2021 ◽  
Vol 57 (6) ◽  
pp. 555
Author(s):  
Adrian Curta ◽  
Holger Hetterich ◽  
Regina Schinner ◽  
Aaron M. Lee ◽  
Wieland Sommer ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Sleep Apnea ◽  
Ejection Fraction ◽  
Right Ventricular ◽  
Cardiac Mri ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
Uk Biobank ◽  
Ventricular Ejection Fraction ◽  
Ventricular Volumes

Background and Objectives: Obstructive sleep apnea (OSA) is a common disorder with an increased risk for left ventricular and right ventricular dysfunction. Most studies to date have examined populations with manifest cardiovascular disease using echocardiography to analyze ventricular dysfunction with little or no reference to ventricular volumes or myocardial mass. Our aim was to explore these parameters with cardiac MRI. We hypothesized that there would be stepwise increase in left ventricular mass and right ventricular volumes from the unaffected, to the snoring and the OSA group. Materials and Methods: We analyzed cardiac MRI data from 4978 UK Biobank participants free from cardiovascular disease. Participants were allocated into three cohorts: with OSA, with self-reported snoring and without OSA or snoring (n = 118, 1886 and 2477). We analyzed cardiac parameters from balanced cine-SSFP sequences and indexed them to body surface area. Results: Patients with OSA were mostly males (47.3% vs. 79.7%; p < 0.001) with higher body mass index (25.7 ± 4.0 vs. 31.3 ± 5.3 kg/m²; p < 0.001 and higher blood pressure (135 ± 18 vs. 140 ± 17 mmHg; p = 0.012) compared to individuals without OSA or snoring. Regression analysis showed a significant effect for OSA in left ventricular end-diastolic index (LVEDVI) (β = −4.9 ± 2.4 mL/m²; p = 0.040) and right ventricular end-diastolic index (RVEDVI) (β = −6.2 ± 2.6 mL/m²; p = 0.016) in females and for right ventricular ejection fraction (RVEF) (β = 1.7 ± 0.8%; p = 0.031) in males. A significant effect was discovered in snoring females for left ventricular mass index (LVMI) (β = 3.5 ± 0.9 g/m²; p < 0.001) and in males for left ventricular ejection fraction (LVEF) (β = 1.0 ± 0.3%; p = 0.001) and RVEF (β = 1.2 ± 0.3%; p < 0.001). Conclusion: Our study suggests that OSA is highly underdiagnosed and that it is an evolving process with gender specific progression. Females with OSA show significantly lower ventricular volumes while males with snoring show increased ejection fractions which may be an early sign of hypertrophy. Separate prospective studies are needed to further explore the direction of causality.

scholarly journals Cardiac structure and function in patients with schizophrenia taking antipsychotic drugs: an MRI study

2019 ◽  
Author(s):  
Toby Pillinger ◽  
Emanuele F. Osimo ◽  
Antonio de Marvao ◽  
Alaine Berry ◽  
Thomas Whitehurst ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Cardiac Mri ◽  
Cardiac Fibrosis ◽  
Left Ventricular ◽  
Myocardial Inflammation ◽  
Antipsychotic Treatment ◽  
Cardiac Structure ◽  
Lv Mass ◽  
Myocardial T1 ◽  
And Function

AbstractCardiovascular disease (CVD) is a major cause of excess mortality in schizophrenia. Preclinical evidence shows antipsychotics can cause myocardial fibrosis and myocardial inflammation in murine models, but it is not known if this is the case in patients. We therefore set out to determine if there is evidence of cardiac fibrosis and/or inflammation using cardiac MRI in medicated patients with schizophrenia compared with matched healthy controls. 31 participants (14 patients and 17 controls) underwent cardiac MRI assessing myocardial markers of fibrosis/inflammation, indexed by native myocardial T1 time, and cardiac structure (left ventricular (LV) mass) and function (left/right ventricular end-diastolic and end-systolic volumes, stroke volumes, and ejection fractions). Participants were physically fit, and matched for age, gender, smoking, blood pressure, BMI, HbA1c, ethnicity, and physical activity. Compared with controls, native myocardial T1 was significantly longer in patients with schizophrenia (effect size, d=0.89; p=0.02). Patients had significantly lower LV mass, and lower left/right ventricular end-diastolic and stroke volumes (effect sizes, d=0.86-1.08; all p-values <0.05). There were no significant differences in left/right end-systolic volumes and ejection fractions between groups (p>0.05). These results suggest an early diffuse fibro-inflammatory myocardial process in patients that is independent of established CVD-risk factors and could contribute to the excess cardiovascular mortality associated with schizophrenia. Future studies are required to determine if this is due to antipsychotic treatment or is intrinsic to schizophrenia.

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