Utility of Quantitative T2 ‐Mapping Compared to Conventional and Advanced Diffusion Weighted Imaging Techniques for Multiparametric Prostate MRI in Men with Hip Prosthesis

Author(s):  
Paul Sathiadoss ◽  
Nicola Schieda ◽  
Mohammad Haroon ◽  
Heba Osman ◽  
Sumaya Alrasheed ◽  
...  
2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Francesco Giganti ◽  
Alex Kirkham ◽  
Veeru Kasivisvanathan ◽  
Marianthi-Vasiliki Papoutsaki ◽  
Shonit Punwani ◽  
...  

AbstractProstate magnetic resonance imaging (MRI) of high diagnostic quality is a key determinant for either detection or exclusion of prostate cancer. Adequate high spatial resolution on T2-weighted imaging, good diffusion-weighted imaging and dynamic contrast-enhanced sequences of high signal-to-noise ratio are the prerequisite for a high-quality MRI study of the prostate. The Prostate Imaging Quality (PI-QUAL) score was created to assess the diagnostic quality of a scan against a set of objective criteria as per Prostate Imaging-Reporting and Data System recommendations, together with criteria obtained from the image. The PI-QUAL score is a 1-to-5 scale where a score of 1 indicates that all MR sequences (T2-weighted imaging, diffusion-weighted imaging and dynamic contrast-enhanced sequences) are below the minimum standard of diagnostic quality, a score of 3 means that the scan is of sufficient diagnostic quality, and a score of 5 implies that all three sequences are of optimal diagnostic quality. The purpose of this educational review is to provide a practical guide to assess the quality of prostate MRI using PI-QUAL and to familiarise the radiologist and all those involved in prostate MRI with this scoring system. A variety of images are also presented to demonstrate the difference between suboptimal and good prostate MR scans.


2019 ◽  
Vol 9 (2) ◽  
pp. 303-307
Author(s):  
Xiubao Song ◽  
Xi Xu ◽  
Yufeng Ye ◽  
Jianye Liang ◽  
Jiaxi Huang ◽  
...  

Objective: Plantar fasciitis is the most common cause of heel pain, which often influence the patient's daily activities. An early and quantitative evaluation helps an effective treatment in plantar fasciitis. Our aims were to explore the feasibility of T2 mapping and intravoxel-incoherent-motion diffusion-weighted imaging (IVIM-DWI) in the quantitative evaluation of plantar fasciitis. Methods: A 3.0T MR scanner was performed on 23 feet of 18 patients with plantar fasciitis and 24 feet of 19 healthy subjects. The imaging protocol consisted of conventional sequences including coronal and sagittal T1- and T2-weighted imaging (T2WI) with and without fat saturation, as well as T2 mapping and IVIM-DWI. The fascial thickness, effusion, tissue edema and other related manifestations were noted. The quantitative parameters including D, D*, f, and T2 values were measured in the fascia, muscle, and subcutaneous fat pad, respectively. Two independent t-test was mainly used for statistical analysis.Results: Qualitatively, bone spur, subcutaneous effusion, and soft tissue edema around the plantar fascia were observed; the fascias were thickened; and the signal intensity of T2WI of soft tissues increased in the patients compared to the healthy subjects. Quantitatively, both D and T2 values were found significant differences in the fascia, muscle, and fat pad between the patients and healthy subjects, except D *; and f values. Conclusions: Both T2 mapping and IVIM-DWI had high clinical values in the quantitative evaluation of plantar fasciitis. D and T2 values may be useful surrogate markers in predicting the severity of plantar fasciitis clinically.


Biomedicines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 1071
Author(s):  
Robert Greite ◽  
Katja Derlin ◽  
Dagmar Hartung ◽  
Rongjun Chen ◽  
Martin Meier ◽  
...  

To characterize ischemia reperfusion injury (IRI)-induced acute kidney injury (AKI) in C57BL/6 (B6) and CD1-mice by longitudinal functional MRI-measurement of edema formation (T2-mapping) and inflammation (diffusion weighted imaging (DWI)). IRI was induced with unilateral right renal pedicle clamping for 35min. 7T-MRI was performed 1 and 14 days after surgery. DWI (7 b-values) and multiecho TSE sequences (7 TE) were acquired. Parameters were quantified in relation to the contralateral kidney on day 1 (d1). Renal MCP-1 and IL-6-levels were measured by qPCR and serum-CXCL13 by ELISA. Immunohistochemistry for fibronectin and collagen-4 was performed. T2-increase on d1 was higher in the renal cortex (127 ± 5% vs. 94 ± 6%, p < 0.01) and the outer stripe of the outer medulla (141 ± 9% vs. 111 ± 9%, p < 0.05) in CD1, indicating tissue edema. Medullary diffusivity was more restricted in CD1 than B6 (d1: 73 ± 3% vs. 90 ± 2%, p < 0.01 and d14: 77 ± 5% vs. 98 ± 3%, p < 0.01). Renal MCP-1 and IL-6-expression as well as systemic CXCL13-release were pronounced in CD1 on d1 after IRI. Renal fibrosis was detected in CD1 on d14. T2-increase and ADC-reduction on d1 correlated with kidney volume loss on d14 (r = 0.7, p < 0.05; r = 0.6, p < 0.05) and could serve as predictive markers. T2-mapping and DWI evidenced higher susceptibility to ischemic AKI in CD1 compared to B6.


Radiographics ◽  
2006 ◽  
Vol 26 (suppl_1) ◽  
pp. S205-S223 ◽  
Author(s):  
Patric Hagmann ◽  
Lisa Jonasson ◽  
Philippe Maeder ◽  
Jean-Philippe Thiran ◽  
Van J. Wedeen ◽  
...  

2017 ◽  
Vol 30 (4) ◽  
pp. 370-384 ◽  
Author(s):  
Neetu Soni ◽  
Nishant Gupta ◽  
Yogesh Kumar ◽  
Manisha Mangla ◽  
Rajiv Mangla

Skull base lesions can be related to wide number of pathologies including infections, benign and malignant tumors. Accurate diagnosis and differentiation between these entities is important for prompt and appropriate treatment. However, computed tomography and routine magnetic resonance imaging techniques only provide information on the extent of the lesions, with limited ability to differentiate between benign and malignant lesions. Diffusion-weighted imaging can help in many such situations by providing additional information, including help in differentiating benign from malignant lesions, so that appropriate treatment can be initiated. In this review article, we illustrate the imaging findings of the spectrum of skull base lesions, emphasizing the role of diffusion-weighted imaging in this domain.


Author(s):  
Dr. Pradeep Kumar Nayak ◽  
Dr. Ajit Kumar

Breast masses range from benign to malignant with varied etiologies. Fibroadenoma the Commonest benign and invasive ductal carcinomas are the commonest malignant lesions. Breast carcinoma is the most common and the second leading cause of deaths in women. It is present fully accepted that breast magnetic resonance is amongst the most sensitive diagnostic imaging techniques for breast lesions. DWI-MR (diffusion weighted magnetic resonance) provides new and different information about the biophysical properties of tissue. The consequent reduction of macroscopic motion effect makes possible the use of DWI in detection and characterization in breast MRI imaging. These facts and figures defines the need for early detection and treatment of breast for favourable prognosis. DWI has sufficient capacity to diagnose invasive, non-invasive breast lesions and has the ability to provide steady, high-resolution tissue images and there is a need to apply DWI to clinical practice while taking advantage of this high contrast resolution. Diffusion weighted Imaging is a potential resource as an adjuvant to breast MRI to differentiate benign from malignant lesions. Such sequence can be easily added to the standard breast magnetic resonance protocol. The present study was planned in Department of Radio- Diagnosis, Katihar Medical College and Hospital, Katihar, Bihar, India. Total 20 cases of the breast lesions refereed to our hospital were evaluated in the present study. Those patients who had come for breast MRI examinations and were detected to have lesions greater than 1 cm in size were included in the study and DWI was performed after obtaining prior consent. Patients who were referred for mammography and sonomammography and who were detected to have solid lesions greater than 1 cm were also included in this study after obtaining prior consent; diffusion-weighted sequences were performed for these patients only to characterize the lesions detected on mammography and sonomammography. The data generated from the present study concludes that DWI for breast lesions can differentiate benign from malignant lesions with a high sensitivity and specificity. The usefulness of this technique needs to be further evaluated with larger double-blind studies. Keywords: Diffusion Weighted Imaging, DWI, Breast Masses, etc.


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