Amide Proton Transfer‐Weighted Imaging and Multiple Models Diffusion‐Weighted Imaging Facilitates Preoperative Risk Stratification of Early‐Stage Endometrial Carcinoma

2021 ◽  
Author(s):  
Nan Meng ◽  
Ting Fang ◽  
Pengyang Feng ◽  
Zhun Huang ◽  
Jing Sun ◽  
...  
Keyword(s):  
Risk Stratification ◽  
Proton Transfer ◽  
Endometrial Carcinoma ◽  
Diffusion Weighted Imaging ◽  
Early Stage ◽  
Amide Proton ◽  
Multiple Models ◽  
Preoperative Risk ◽  
Amide Proton Transfer ◽  
Preoperative Risk Stratification

scholarly journals Amide proton transfer imaging in differentiation of type II and type I endometrial carcinoma: a pilot study

2021 ◽  
Author(s):  
Ryoya Ochiai ◽  
Naoko Mukuda ◽  
Hiroto Yunaga ◽  
Shinichiro Kitao ◽  
Kyohei Okuda ◽  
...  
Keyword(s):  
Proton Transfer ◽  
Endometrial Carcinoma ◽  
Sensitivity And Specificity ◽  
Amide Proton ◽  
Magnetization Transfer Ratio ◽  
Type I ◽  
Type Ii ◽  
Amide Proton Transfer ◽  
Apt Imaging ◽  
Significant Difference

Abstract Purpose This study aimed at evaluating the efficacy of amide proton transfer (APT) imaging in differentiation of type II and type I uterine endometrial carcinoma. Materials and methods Thirty-three patients diagnosed with uterine endometrial carcinoma, including 24 with type I and 9 with type II carcinomas, underwent APT imaging. Two readers evaluated the magnetization transfer ratio at 3.5 ppm [MTRasym (3.5 ppm)] in each type of carcinoma. The average MTRasym (APTmean) and the maximum MTRasym (APTmax) were analyzed. The receiver operating characteristic (ROC) curve analysis was performed. Results The APTmax was significantly higher in type II carcinomas than in type I carcinomas (reader1, p = 0.004; reader 2, p = 0.014; respectively). However, APTmean showed no significant difference between type I and II carcinomas. Based on the results reported by reader 1, the area under the curve (AUC) pertaining to the APTmax for distinguishing type I from type II carcinomas was 0.826, with a cut-off, sensitivity, and specificity of 9.90%, 66.7%, and 91.3%, respectively. Moreover, based on the results reported by reader 2, the AUC was 0.750, with a cut-off, sensitivity, and specificity of 9.80%, 62.5%, and 87.5%, respectively. Conclusion APT imaging has the potential to determine the type of endometrial cancer.

scholarly journals Endometrial Carcinoma: MR Imaging–based Texture Model for Preoperative Risk Stratification—A Preliminary Analysis

Radiology ◽  
2017 ◽  
Vol 284 (3) ◽  
pp. 748-757 ◽  
Author(s):  
Yoshiko Ueno ◽  
Behzad Forghani ◽  
Reza Forghani ◽  
Anthony Dohan ◽  
Xing Ziggy Zeng ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Risk Stratification ◽  
Endometrial Carcinoma ◽  
Preliminary Analysis ◽  
Preoperative Risk ◽  
Texture Model ◽  
Preoperative Risk Stratification
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