Contrast‐Enhanced MRI Combined With the Glycerol Test Reveals the Heterogeneous Dynamics of Endolymphatic Hydrops in Patients With Menière's Disease

2020 ◽  
Vol 52 (4) ◽  
pp. 1066-1073
Author(s):  
Pengjun Wang ◽  
Dongzhen Yu ◽  
Hui Wang ◽  
Haibo Ye ◽  
Ruihua Qiao ◽  
...  
Keyword(s):  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Heterogeneous Dynamics ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Ménière's Disease ◽  
Glycerol Test ◽  
Contrast Enhanced Mri

Endolymphatic hydrops precipitated by haemodialysis

1990 ◽  
Vol 104 (8) ◽  
pp. 641-642 ◽  
Author(s):  
D. A. Moffat ◽  
V. L. Cumberworth ◽  
D. M. Baguley
Keyword(s):  
Endolymphatic Hydrops ◽  
Plasma Osmolality ◽  
Meniere’S Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Electrophysiological Recordings ◽  
Ménière's Disease ◽  
Contralateral Ear ◽  
Sudden Decrease ◽  
Glycerol Test

AbstractWe report a case of endolymphatic hydrops preceded by haemodialysis in the contralateral ear of a patient with known Menière's disease, and discuss the possible mechanism. It is suggested that the sudden decrease of plasma osmolality during haemodialysis acts as a reverse glycerol test. The audiometric and electrophysiological recordings pre- and post- dialysis and the induction of the Menière's triad of symptoms during dialysis, were strongly indicative of the presence of endolymphatic hydrops.

S233 – Diagnostic Role of Electrocochleography after Glycerol Test

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P153-P153
Author(s):  
Mohammadreza Majidi ◽  
Mokhtari Nematollah ◽  
Tale Mohammadreza ◽  
Rauf Aliasghar ◽  
Mohammad Taghi Shakeri
Keyword(s):  
Pure Tone ◽  
Endolymphatic Hydrops ◽  
Pure Tone Audiometry ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
Glycerol Test

Objectives Response to dehydrating agents such as glycerol in Meniere's disease is evaluated by audiometric shifts after substance administration. Since the major pathogenic event in this disease is endolymphatic hydrops, evidenced by elevated SP/AP ratio, this study was conducted to determine the value of electrochochleography in assessment of response to glycerol administration in patients with definite Meniere's disease. Methods Between October 2006 and December 2007, 12 women and 10 men with definite Meniere's disease, based on AAO-HNS guidelines during acute phase, were included in this study. Pure tone audiometry (before and 1,2,3 hours after glycerol administration) and extratympanic electrocochleography (before and 3 hours after test) were performed; improvement in tinnitus, aural fullness, and vertigo symptoms were recorded after glycerol administration. Chi-square test was used to compare the sensitivity of electrocochleography and pure tone audiometry for detection of response to glycerol test. Results 22 patients, mean age of 40.18±8.8 years, were included in this study. Of 16 patients with tinnitus complaint, 9 patients reported significant improvement after glycerol test. Of 22 patients with vertigo and aural fullness symptoms, 19 reported significant clinical improvement. The SP/AP ratio was significantly reduced and reached to less than 80% of pretest values in 17 of these patients, but improvement in pure tone thresholds was observed in 8 patients. The difference between 2 methods was significant (p<0.05). Conclusions It seems that significant reduction in SP/AP ratio in patients with Meniere's disease might be a more sensitive indicator of the response to glycerol test than pure tone threshold shifts.

Rupture-Like Shrinkage and Regrowth of Endolymphatic Hydrops in Ménière's Disease During Remission

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Munehisa Fukushima ◽  
Yu Suekata ◽  
Takuya Kusumoto ◽  
Shiro Akahani ◽  
Hidehiko Okamoto ◽  
...  
Keyword(s):  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease

Endolymphatic hydrops and therapeutic effects are visualized in ‘atypical’ Meniere's disease

2009 ◽  
Vol 129 (11) ◽  
pp. 1326-1329 ◽  
Author(s):  
Maiko Miyagawa ◽  
Hisakuni Fukuoka ◽  
Keita Tsukada ◽  
Tomohiro Oguchi ◽  
Yutaka Takumi ◽  
...  
Keyword(s):  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Therapeutic Effects ◽  
Menière's Disease ◽  
Ménière's Disease

scholarly journals Endolymphatic Hydrops in Patients With Vestibular Migraine and Concurrent Meniere's Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Sun-Young Oh ◽  
Marianne Dieterich ◽  
Bit Na Lee ◽  
Rainer Boegle ◽  
Jin-Ju Kang ◽  
...  
Keyword(s):  
Inner Ear ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Vestibular Migraine ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Volumetric Quantification ◽  
Ménière's Disease

Objective: Intravenous contrast agent enhanced, high-resolution magnetic resonance imaging of the inner ear (iMRI) confirmed that patients with Menière's disease (MD) and vestibular migraine (VM) could present with endolymphatic hydrops (EH). The present study aimed to investigate EH characteristics and their interrelation to neurotologic testing in patients with VM, MD, or VM with concurrent MD (VM-MD).Methods: Sixty–two patients (45 females, aged 23–81 years) with definite or probable VM (n = 25, 19 definite), MD (n = 29, 17 definite), or showing characteristics of both diseases (n = 8) were included in this study. Diagnostic workup included neurotologic assessments including video-oculography (VOG) during caloric stimulation and head-impulse test (HIT), ocular and cervical vestibular evoked myogenic potentials (o/cVEMP), pure tone audiometry (PTA), as well as iMRI. EH's degree was assessed visually and via volumetric quantification using a probabilistic atlas-based segmentation of the bony labyrinth and volumetric local thresholding (VOLT).Results: Although a relevant number of VM patients reported varying auditory symptoms (13 of 25, 52.0%), EH in VM was only observed twice. In contrast, EH in VM-MD was prevalent (2/8, 25%) and in MD frequent [23/29, 79.3%; χ2(2) = 29.1, p &lt; 0.001, φ = 0.7]. Location and laterality of EH and neurophysiological testing classifications were highly associated (Fisher exact test, p &lt; 0.005). In MD, visual semi-quantitative grading and volumetric quantification correlated highly to each other (rS = 0.8, p &lt; 0.005, two-sided) and to side differences in VOG during caloric irrigation (vestibular EH ipsilateral: rS = 0.6, p &lt; 0.05, two-sided). In VM, correlations were less pronounced. VM-MD assumed an intermediate position between VM and MD.Conclusion: Cochlear and vestibular hydrops can occur in MD and VM patients with auditory symptoms; this suggests inner ear damage irrespective of the diagnosis of MD or VM. The EH grades often correlated with auditory symptoms such as hearing impairment and tinnitus. Further research is required to uncover whether migraine is one causative factor of EH or whether EH in VM patients with auditory symptoms suggests an additional pathology due to MD.

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