MRI‐based risk factors of hepatocellular carcinoma in patients with chronic liver disease: A prospective observational study

2019 ◽  
Vol 51 (2) ◽  
pp. 389-396 ◽  
Author(s):  
Tatsuya Shimizu ◽  
Utaroh Motosugi ◽  
Nobutoshi Komatsu ◽  
Shintaro Ichikawa ◽  
Taisuke Inoue ◽  
...  
1993 ◽  
Vol 328 (25) ◽  
pp. 1797-1801 ◽  
Author(s):  
Hideaki Tsukuma ◽  
Tomohiko Hiyama ◽  
Sachiko Tanaka ◽  
Miho Nakao ◽  
Takako Yabuuchi ◽  
...  

2012 ◽  
Vol 23 (3) ◽  
pp. 455-462 ◽  
Author(s):  
Nghi B. Ha ◽  
Nghiem B. Ha ◽  
Aijaz Ahmed ◽  
Walid Ayoub ◽  
Tami J. Daugherty ◽  
...  

2020 ◽  
Vol 10 (5-s) ◽  
pp. 19-24
Author(s):  
Samreen Huma ◽  
Omer Nishat Fatima ◽  
Ishrath Ayesha ◽  
Jamal Mohammed Moiz ◽  
Shareef Mohammed Mohiuddin

Objectives: To study the prescribing pattern of drugs & its use in the treatment of CLD & assess the pattern of co-morbidities associated with CLD. To Study the mortality rate of the patient using MELD score at a department of general medicine at Osmania general Hospital to produce a result which would aid better rational drug use and improve quality of life. Methodology: A Prospective, observational study was carried out at OGH for a period of 6 months in 100 old patients. Population of either sex or ≥ 18 years of age were included. Conclusion: There is a considerable scope for improving prescribing pattern in CLD by minimizing the use, reduction of doses of drugs to reduce the consequence of hepatotoxicity and Antibiotic Resistance. The prognostic impact of individual comorbidities, on the other hand, may point to areas where cirrhosis and comorbid diseases interact. Studies of individual comorbidities may therefore improve our understanding of the pathophysiology of cirrhosis. MELD showed that the subjects were less likely to get a Liver transplant. Keywords: Chronic liver disease (CLD), Model for end stage liver disease (MELD), Diabetes Mellitus (DM), hypertension (HTN)


Author(s):  
Tsai-Wing Ow ◽  
Evangelia Fatourou ◽  
Liane Rabinowich ◽  
Bente Pernille van den Boom ◽  
Shirjit Nair ◽  
...  

Introduction: Haemorrhage and venous thromboembolism (VTE) are recognised complications of chronic liver disease (CLD), but their prevalence and risk factors in critically ill patients is uncertain. Patients and methods: We studied a retrospective cohort of patients with CLD non-electively admitted to a specialist intensive care unit determining the prevalence and timing of major bleeding and VTE (early, present on admission/diagnosed within 48h; later diagnosed >48h post ICU admission). Associations with baseline clinical and laboratory characteristics, multi-organ failure (MOF), blood product administration and mortality were explored. Odds ratios (OR) and 95% CIs were calculated using logistic regression. Results: Of 623 patients with median age 52, bleeding (>48 hours after admission) occurred in 87 (14%) patients. Bleeding was associated with greater illness severity and increased mortality. Gastrointestinal bleeding accounted for 72% of events, secondary to portal hypertension in >90%. Procedure-related bleeding was uncommon. VTE occurred in 125 (20%) patients: Early VTE in 80 (13%) and involving the portal vein (PVT) in 85%. Later VTE affected 45 (7.2%) patients. Hepatocellular Carcinoma (HCC) and non-alcoholic liver disease were independently associated with early VTE (OR 2.79, (95% CI 1.5 -5.2) and 2.32, (1.4 -3.9) respectively), and HCC, sepsis and cryoprecipitate use with late VTE (OR 2.45, (1.11-5.43), 2.26 (1.2-4.3) and 2.60 (1.3-5.1). Conclusion: VTE was prevalent on admission to critical care and less commonly developed later. Bleeding was associated with MOF and increased mortality. Severe MOF was not associated with an increased rate of VTE which was linked with HCC, and specific etiologies of CLD.


Radiology ◽  
2013 ◽  
Vol 266 (2) ◽  
pp. 480-490 ◽  
Author(s):  
Tomoko Hyodo ◽  
Takamichi Murakami ◽  
Yasuharu Imai ◽  
Masahiro Okada ◽  
Masatoshi Hori ◽  
...  

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