scholarly journals Highly-accelerated volumetric brain examination using optimized wave-CAIPI encoding

2019 ◽  
Vol 50 (3) ◽  
pp. 961-974 ◽  
Author(s):  
Daniel Polak ◽  
Stephen Cauley ◽  
Susie Y. Huang ◽  
Maria Gabriela Longo ◽  
John Conklin ◽  
...  
Keyword(s):  
Author(s):  
Z. Kayun ◽  
M.K.A. Karim ◽  
N.A. Muhammad ◽  
O.B. Aljewaw ◽  
C.M. Tsuey ◽  
...  

Author(s):  
Visakh T ◽  
Suresh Sukumar ◽  
Abhimanyu Pradhan

Objective: The objective of this study was to estimate the entrance surface radiation dose to the thyroid region in a computed tomography (CT) brain scan.Methods: Unfors Multi-O-Meter equipment was used to measure the entrance surface at the thyroid region of adult patients ranging from 18 to 70 years of age. A total of 115 patients were included in the study based on convenience sampling. The Multi-O-Meter was kept at the thyroid region during the scan, and the values for entrance surface dose (ESD) were noted from its monitor after the scan was complete.Results: The obtained data were analyzed and violate normal distribution; therefore, the median and quartiles were computed. The overall median (Q1, Q2), ESD of the patients, was 1.335 (1.213, 1.529) mGy. The minimum and maximum dose values recorded were 1.015 mGy and 1.964 mGy, respectively.Conclusions: The result showed a significant amount of entrance surface radiation dose to the thyroid region while taking a brain scan. This data can be used for optimization of radiation protection while undergoing CT scans of brain to reduce exposure to thyroid region.


2021 ◽  
pp. practneurol-2021-003058
Author(s):  
Rhea YY Tan ◽  
Anna M Drazyk ◽  
Kathryn Urankar ◽  
Clare Bailey ◽  
Stefan Gräf ◽  
...  

A 44-year-old Caucasian man presented with seizures and cognitive impairment. He had marked retinal drusen, and MR brain scan showed features of cerebral small vessel disease; he was diagnosed with a leukoencephalopathy of uncertain cause. He died at the age of 46 years and postmortem brain examination showed widespread small vessel changes described as a vasculopathy of unknown cause. Seven years postmortem, whole-genome sequencing identified a homozygous nonsense HTRA1 mutation (p.Arg302Ter), giving a retrospective diagnosis of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy.


Author(s):  
Siti Masrochah ◽  
Yeti Kartikasari ◽  
Ayu Mahanani

The purpose of the research is to identify the differences between image information of MRI Brain in axial plane Diffusion Weighted Image (DWI) sequence and variation b value in case ischemic stroke, and to determine optimal b value in examination MRI Brain in case Ischemic Stroke. This research was a quantitative research with experimental approach. This research was done in Panti Rapih Hospital, Yogyakarta and used 8 ischemic stroke patients with 3 variasion b value (500s/mm2, 1000 s/mm2, 1500 s/mm2) and 3 radiologists as respondents. The data were analyzed using Friedman test. Result showed that there was difference between image information of MRI Brain in axial plane Diffusion Weighted Image (DWI) sequence and variation b value in case ischemic stroke with p0.05 which means there is a difference between Basal Ganglia, Cerebellum, and the border of the infarction. Meanwhile, Cortex Cerebri, Thalamus and Pons obtained no difference in image information and the optimal b value for MRI Brain examination of ischemic stroke 1500 s/mm2. Based on the result there was a difference  between image information of MRI Brain in axial plane Diffusion Weighted Image (DWI) sequence and variation b value in case ischemic stroke. Optimal value of variation b value for MRI Brain examination of ischemic stroke was 1500 s/mm2.


Author(s):  
Stephen J. Sozio ◽  
Yanhong Bian ◽  
Steven J. Marshall ◽  
Zorimar Rivera-Núñez ◽  
Salvatore Bacile ◽  
...  

1993 ◽  
Vol 289 (3) ◽  
pp. 719-725 ◽  
Author(s):  
E B Borthwick ◽  
A Burchell ◽  
M W Coughtrie

Sulphation of oestrogens represents an important regulatory mechanism for these biologically active compounds. We have characterized and purified a form of rat liver sulphotransferase (ST), existing as a 32,500 Da monomer, which sulphates oestrogens, and have used this preparation to produce antibodies against oestrogen ST. The enzyme was active against oestrone, oestriol and beta-oestradiol, but not towards androgens. Using the antibody as a probe for immunoblotting, it was determined that the enzyme is expressed solely in male rats, and predominantly in the liver. Of the tissues examined, the only major extrahepatic tissue found to have any oestrogen ST was the brain (although the levels were very low), indicating that there might be a role for the sulphation of oestrogens in the brain. Examination of human liver and platelet cytosols by immunoblotting showed that the antibody recognized two major proteins of 32 and 34 kDa, which were presumed to correspond to the two principal phenol ST isoenzymes present in man.


2010 ◽  
Vol 13 (4) ◽  
pp. 754-758 ◽  
Author(s):  
Toshihide Monden ◽  
Nobuyuki Kudomi ◽  
Yasuhiro Sasakawa ◽  
Yuka Yamamoto ◽  
Nobuyuki Kawai ◽  
...  

Author(s):  
Visakh T ◽  
Suresh Sukumar ◽  
Abhimanyu Pradhan

Objective: The objective of this study was to estimate the entrance surface radiation dose to the thyroid region in a computed tomography (CT) brain scan.Methods: Unfors Multi-O-Meter equipment was used to measure the entrance surface at the thyroid region of adult patients ranging from 18 to 70 years of age. A total of 115 patients were included in the study based on convenience sampling. The Multi-O-Meter was kept at the thyroid region during the scan, and the values for entrance surface dose (ESD) were noted from its monitor after the scan was complete.Results: The obtained data were analyzed and violate normal distribution; therefore, the median and quartiles were computed. The overall median (Q1, Q2), ESD of the patients, was 1.335 (1.213, 1.529) mGy. The minimum and maximum dose values recorded were 1.015 mGy and 1.964 mGy, respectively.Conclusions: The result showed a significant amount of entrance surface radiation dose to the thyroid region while taking a brain scan. This data can be used for optimization of radiation protection while undergoing CT scans of brain to reduce exposure to thyroid region.


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