scholarly journals Evaluation of Effects of TGF‐β1 Inhibition on Gastric Cancer in Nude Mice by Diffusion Kurtosis Imaging and In‐Line X‐ray Phase Contrast Imaging With Sequential Histology

2018 ◽  
Vol 49 (6) ◽  
pp. 1553-1564 ◽  
Author(s):  
Bowen Shi ◽  
Fei Yuan ◽  
Fuhua Yan ◽  
Huan Zhang ◽  
Zilai Pan ◽  
...  
2013 ◽  
Vol 718-720 ◽  
pp. 2099-2102
Author(s):  
Qiang Tao ◽  
Shu Qian Luo

The hard X-ray in-line phase contrast imaging (HXILPCI) is a phase contrast technique that generates excellent contrast of biological soft tissues compared to conventional X-ray absorption radiography. We explore the application of HXILPCI in the diagnosis of gastric cancer and pancreatic cancer. These nude mice cancer samples were checked by HXILPCI to obtain projection contrast images of 9μm image resolution with CCD camera. The texture extraction was based on gray level co-occurrence matrix (GLCM). The corresponding morphological features of abnormal and normal tissues are analyzed. The produced phase contrast images of nude mice cancer samples show clearly biological tissues architectures and the size of cancer. The paper results show that HXILPCI can be a potential noninvasive technique to diagnose early cancer.


2020 ◽  
Vol 64 (2) ◽  
pp. 20503-1-20503-5
Author(s):  
Faiz Wali ◽  
Shenghao Wang ◽  
Ji Li ◽  
Jianheng Huang ◽  
Yaohu Lei ◽  
...  

Abstract Grating-based x-ray phase-contrast imaging has the potential to enhance image quality and provide inner structure details non-destructively. In this work, using grating-based x-ray phase-contrast imaging system and employing integrating-bucket method, the quantitative expressions of signal-to-noise ratios due to photon statistics and mechanical error are analyzed in detail. Photon statistical noise and mechanical error are the main sources affecting the image noise in x-ray grating interferometry. Integrating-bucket method is a new phase extraction method translated to x-ray grating interferometry; hence, its image quality analysis would be of great importance to get high-quality phase image. The authors’ conclusions provide an alternate method to get high-quality refraction signal using grating interferometer, and hence increases applicability of grating interferometry in preclinical and clinical usage.


Author(s):  
Jianheng Huang ◽  
Yaohu Lei ◽  
Xin Liu ◽  
Jinchuan Guo ◽  
Ji Li ◽  
...  

2021 ◽  
Vol 11 (7) ◽  
pp. 2971
Author(s):  
Siwei Tao ◽  
Congxiao He ◽  
Xiang Hao ◽  
Cuifang Kuang ◽  
Xu Liu

Numerous advances have been made in X-ray technology in recent years. X-ray imaging plays an important role in the nondestructive exploration of the internal structures of objects. However, the contrast of X-ray absorption images remains low, especially for materials with low atomic numbers, such as biological samples. X-ray phase-contrast images have an intrinsically higher contrast than absorption images. In this review, the principles, milestones, and recent progress of X-ray phase-contrast imaging methods are demonstrated. In addition, prospective applications are presented.


2021 ◽  
Vol 1787 (1) ◽  
pp. 012027
Author(s):  
S S Makarov ◽  
T A Pikuz ◽  
A V Buzmakov ◽  
A P Chernyaev ◽  
P Mabey ◽  
...  

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