scholarly journals Feasibility study of a single breath-hold, 3D mDIXON pulse sequence for late gadolinium enhancement imaging of ischemic scar

2018 ◽  
Vol 49 (5) ◽  
pp. 1437-1445 ◽  
Author(s):  
James R.J. Foley ◽  
Graham J. Fent ◽  
Pankaj Garg ◽  
David A. Broadbent ◽  
Laura E. Dobson ◽  
...  
2021 ◽  
Vol 161 ◽  
pp. S1488-S1489
Author(s):  
V. Maradia ◽  
S. Bertschi ◽  
M. Krieger ◽  
S. van de Water ◽  
D. Meer ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Anish N. Bhuva ◽  
Thomas A. Treibel ◽  
Andreas Seraphim ◽  
Paul Scully ◽  
Kristopher D. Knott ◽  
...  

Background: Measurement of myocardial T1 is increasingly incorporated into standard cardiovascular magnetic resonance (CMR) protocols, however accuracy may be reduced in patients with metallic cardiovascular implants. Measurement is feasible in segments free from visual artifact, but there may still be off-resonance induced error.Aim: To quantify off-resonance induced T1 error in patients with metallic cardiovascular implants, and validate a method for error correction for a conventional MOLLI pulse sequence.Methods: Twenty-four patients with cardiac implantable electronic devices (CIEDs: 46% permanent pacemakers, PPMs; 33% implantable loop recorders, ILRs; and 21% implantable cardioverter-defibrillators, ICDs); and 31 patients with aortic valve replacement (AVR) (45% metallic) were studied. Paired mid-myocardial short-axis MOLLI and single breath-hold off-resonance field maps were acquired at 1.5 T. T1 values were measured by AHA segment, and segments with visual artifact were excluded. T1 correction was applied using a published relationship between off-resonance and T1. The accuracy of the correction was assessed in 10 healthy volunteers by measuring T1 before and after external placement of an ICD generator next to the chest to generate off-resonance.Results: T1 values in healthy volunteers with an ICD were underestimated compared to without (967 ± 52 vs. 997 ± 26 ms respectively, p = 0.0001), but were similar after correction (p = 0.57, residual difference 2 ± 27 ms). Artifact was visible in 4 ± 12, 42 ± 31, and 53 ± 27% of AHA segments in patients with ILRs, PPMs, and ICDs, respectively. In segments without artifact, T1 was underestimated by 63 ms (interquartile range: 7–143) per patient. The greatest error for patients with ILRs, PPMs and ICDs were 79, 146, and 191 ms, respectively. The presence of an AVR did not generate T1 error.Conclusion: Even when there is no visual artifact, there is error in T1 in patients with CIEDs, but not AVRs. Off-resonance field map acquisition can detect error in measured T1, and a correction can be applied to quantify T1 MOLLI accurately.


Radiology ◽  
2002 ◽  
Vol 222 (1) ◽  
pp. 278-283 ◽  
Author(s):  
Audrey L. Spielmann ◽  
Rendon C. Nelson ◽  
Carolyn R. Lowry ◽  
G. Allan Johnson ◽  
Gopal Sundaramoothy ◽  
...  

Author(s):  
Joseph Selvanayagam ◽  
Gaetano Nucifora

The peculiar features of gadolinium-chelated contrast agents and the development of contrast-enhanced inversion recovery technique in the late 1990s formed the basis of early and late gadolinium enhancement imaging, revolutionizing the application of magnetic resonance imaging in patients with cardiac diseases. Several clinical studies have indeed demonstrated the clinical benefits of early and late gadolinium enhancement imaging, including the discrimination between scarred/fibrotic myocardium and normal myocardium and the identification of mural thrombi and areas of microvascular obstruction among patients with acute myocardial infarction. The technique currently plays a key role in the differential diagnosis between cardiac diseases with ischaemic and non-ischaemic aetiology and in the assessment of patients with acute myocardial infarction and its complications. Due to its invaluable ability to provide diagnostic and prognostic information, it is indeed more frequently implemented for patients’ clinical management and decision-making. This chapter discusses the technical aspects of early and late gadolinium enhancement imaging, reviews the initial studies that led to the validation of the technique, and focuses on its application according to the main clinical syndromes (i.e. acute and chronic myocardial infarction, heart failure, conduction diseases, and ventricular arrhythmias). Guidelines for correct image acquisition and interpretation will be also provided, in particular, how to deal with patients with cardiac arrhythmias or with patients unable to breath-hold properly, and how to discriminate true late gadolinium enhancement areas from artefacts is discussed.


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